Persistent organic pollutants in fish: biomonitoring and cocktail effect with implications for food safety

Panseri, Sara; Chiesa, Luca Maria; Ghisleni, Gabriele; Marano, Giuseppe; Boracchi, Patrizia; Ranghieri, Valerio; Malandra, Renato; Roccabianca, P.; Tecilla, Marco

doi:10.1080/19440049.2019.1579926

Cited by 35 publications

(23 citation statements)

References 37 publications

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“…The analysis of per-and polyfluoroalkyl substances in the fish fillet was performed as described elsewhere [7,30]. Briefly,~3 g of sample were spiked with the ISs at the concentration of 5 ng/mL and 10 mL of acetonitrile were added for extraction and protein precipitation.…”

Section: Analysis Of Per-and Polyfluoroalkyl Substances (Pfass)mentioning

confidence: 99%

“…The methods were checked for their linearity, repeatability, recovery, limit of detection (LOD), and quantification (LOQ), as reported in Table S3 according to the SANTE 2017 [31] guidelines and our previous studies [7,29,30]. The LOD and LOQ for each analyzed compound were calculated from the calibration curve in the concentration range corresponding to the lower concentration levels according to MRL for each compound, when available.…”

Section: Quality Assurance and Quality Controlmentioning

confidence: 99%

“…The consumption of local fishery products is considered the main exposure pathway to environmental contaminants, particularly persistent and bioaccumulative ones, and can represent a potential risk for human health [7,29,35]. The extremely low levels of contamination in fish caught in Southern Norway might be due to the homogeneously low weights and sizes due to the young age of the examined fish as compared with data on FishBase [36] and suggest no potential implications for food safety.…”

Section: Human Exposurementioning

confidence: 99%

“…Fish species play a pivotal ecological role in aquatic ecosystems and can accumulate to a great extent in a great number of lipophilic contaminants [4]. For this reason, fish species are commonly used to biomonitor the levels of organic contaminants worldwide and the potential implication for human health [5][6][7]. Although several monitoring surveys have demonstrated that the levels of some groups of halogenated compounds, such as PCBs and PBDEs, are declining in the marine ecosystems during the last decades [8][9][10], notable concentrations of these contaminants are still measured in fish from various geographical areas [10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

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Legacy and Emerging Contaminants in Demersal Fish Species from Southern Norway and Implications for Food Safety

Parolini

Panseri

Gaeta

et al. 2020

Foods

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The present study aimed at measuring the levels of legacy and emerging contaminants in fillet samples from four demersal fish caught in two fishing sites from Southern Norway, in order to assess possible implications for food safety. Levels of organochlorine compounds (OCs), organophosphate pesticides (OPs), polychlorinated biphenyls (PCBs), polybromodiphenyl ethers (PBDE), per- and polyfluoroalkyl substances (PFASs), and polycyclic aromatic hydrocarbons (PAHs) were measured in fillet from Atlantic cod (Gadus morhua), European plaice (Pleuronectes platessa), lemon sole (Microstomus kitt), and European flounder (Platichthys flesus) specimens. A negligible contamination by all the investigated chemicals was noted in both the fishing sites, as very low levels of OCs, PCBs, and PFASs were noted in a limited number of individuals for each species. Considering the levels of contaminants measured in fillets of the four demersal fish species, negligible risk for human health for Norwegian consumers can be supposed.

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Section: Analysis Of Per-and Polyfluoroalkyl Substances (Pfass)mentioning

confidence: 99%

Section: Quality Assurance and Quality Controlmentioning

confidence: 99%

Section: Human Exposurementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Legacy and Emerging Contaminants in Demersal Fish Species from Southern Norway and Implications for Food Safety

Parolini

Panseri

Gaeta

et al. 2020

Foods

Self Cite

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“…So, they are easily incorporated into the food chain, bioaccumulation, and biomagnification [5]. Regarding their toxicity mechanisms, it has been described that they can act as endocrine disruptors and as reactive species that generate oxidative stress in the cell [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Plant Metabolites in Plant Defense Against Pathogens

Ramírez-Gómez¹,

Jiménez-García²,

Campos³

et al. 2020

Plant Diseases - Current Threats and Management Trends

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Medicinal plants are widely used worldwide to treat various diseases. Its widespread use is due in part to the cultural acceptance of traditional medicine in different regions of the world, as well as its effectiveness in treating various diseases. Many of its active substances or secondary metabolites are formed to a response of various situations that generate stress in their habitat, such as sudden changes in environmental temperature, humidity, rain, drought, and infections by phytopathogens (fungi, bacteria, viruses, nematodes, protozoa). The production of these secondary metabolites is a mechanism of defense of plants. In this context, the objective of this chapter is to study the secondary metabolites of medicinal plants that could have a promising application in the control of different phytopathogens in crops of agricultural and economic interest.

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Disruption of small molecule transporter systems by Transporter‐Interfering Chemicals (TICs)

Nicklisch

Hamdoun

2020

FEBS Letters

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Small molecule transporters (SMTs) in the ABC and SLC families are important players in disposition of diverse endo-and xenobiotics. Interactions of environmental chemicals with these transporters were first postulated in the 1990s, and since validated in numerous in vitro and in vivo scenarios. Recent results on the co-crystal structure of ABCB1 with the flame-retardant BDE-100 demonstrate that a diverse range of man-made and natural toxic molecules, hereafter termed transporter-interfering chemicals (TICs), can directly bind to SMTs and interfere with their function. TIC-binding modes mimic those of substrates, inhibitors, modulators, inducers, and possibly stimulants through direct and allosteric mechanisms. Similarly, the effects could directly or indirectly agonize, antagonize or perhaps even prime the SMT system to alter transport function. Importantly, TICs are distinguished from drugs and pharmaceuticals that interact with transporters in that exposure is unintended and inherently variant. Here, we review the molecular mechanisms of environmental chemical interaction with SMTs, the methodological considerations for their evaluation, and the future directions for TIC discovery.

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Persistent organic pollutants in fish: biomonitoring and cocktail effect with implications for food safety

Cited by 35 publications

References 37 publications

Legacy and Emerging Contaminants in Demersal Fish Species from Southern Norway and Implications for Food Safety

Legacy and Emerging Contaminants in Demersal Fish Species from Southern Norway and Implications for Food Safety

Plant Metabolites in Plant Defense Against Pathogens

Disruption of small molecule transporter systems by Transporter‐Interfering Chemicals (TICs)

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