Persian Version of Functional Assessment of Cancer Therapy- Breast (FACT-B) Scale: Confirmatory Factor Analysis and Psychometric Properties

Patoo, Mozhgan; Allahyari, Abbas Ali; Moradi, Alireza; Payandeh, Mehrdad

doi:10.7314/apjcp.2015.16.9.3799

Cited by 26 publications

(29 citation statements)

References 17 publications

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“…Two items were reassigned to the physical well-being, five items to the emotional well-being and two items to the functional well-being subscale, while no item was reassigned to the social/family well-being subscale. These findings are in agreement with results from statistical analyses of the English and the Korean version of FACT-B, both showing statistically significant correlations between BCS score and the scores on physical, emotional and functional subscale scores (0.39–0.61), but lower correlation between BCS and social/family subscale (0.09–0.37) ( 30 , 31 , 33 ). In addition, while correlations between items within a subscale are inherently accounted for through the latent well-being variable, additional correlations between well-being in the different subscale were estimated.…”

Section: Discussionsupporting

confidence: 90%

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

Schindler

Friberg

Lum³

et al. 2018

Pharm Res

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PurposeAn item response theory (IRT) pharmacometric framework is presented to characterize Functional Assessment of Cancer Therapy-Breast (FACT-B) data in locally-advanced or metastatic breast cancer patients treated with ado-trastuzumab emtansine (T-DM1) or capecitabine-plus-lapatinib.MethodsIn the IRT model, four latent well-being variables, based on FACT-B general subscales, were used to describe the physical, social/family, emotional and functional well-being. Each breast cancer subscale item was reassigned to one of the other subscales. Longitudinal changes in FACT-B responses and covariate effects were investigated.ResultsThe IRT model could describe both item-level and subscale-level FACT-B data. Non-Asian patients showed better baseline social/family and functional well-being than Asian patients. Moreover, patients with Eastern Cooperative Oncology Group performance status of 0 had better baseline physical and functional well-being. Well-being was described as initially increasing or decreasing before reaching a steady-state, which varied substantially between patients and subscales. T-DM1 exposure was not related to any of the latent variables. Physical well-being worsening was identified in capecitabine-plus-lapatinib-treated patients, whereas T-DM1-treated patients typically stayed stable.ConclusionThe developed framework provides a thorough description of FACT-B longitudinal data. It acknowledges the multi-dimensional nature of the questionnaire and allows covariate and exposure effects to be evaluated on responses.Electronic supplementary materialThe online version of this article (10.1007/s11095-018-2403-8) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 90%

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

Schindler

Friberg

Lum³

et al. 2018

Pharm Res

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“…The Cronbach alpha coefficient for the breast subscale was 0.59 in Wan study on the Chinese version of FACT-B scale. [25] But the findings of this study show that the reliability is appropriate. Cronbach alpha reliability coefficient for total scale is 0.902.…”

Section: Discussionmentioning

confidence: 80%

Bc-Prom

Zhang²,

Zhang³

2017

Medicine

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“…Using IRT, estimation of parameters is independent the number of measured subjects. It is also possible to indicate the accuracy of the test capability [ 38 – 40 ]. Besides statistical methods, clinical professional knowledge was also required during the process of item selection.…”

Section: Discussionmentioning

confidence: 99%

CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure

Tian

Xue

et al. 2018

Health Qual Life Outcomes

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BackgroundDue to a lack of an appropriate disease-specific patient-reported outcome (PRO) instrument for chronic heart failure including its social support and treatment aspects in China, this study was performed to develop a patient-reported outcome measure (PROM) for patients with chronic heart failure and evaluate its reliability, validity, and feasibility.MethodsAccording to the standard PROM guidelines established by the Food and Drug Administration, an item pool was formed by reviewing a large amount of relevant literature and interviewing patients with chronic heart failure about their main symptoms. Thus, the primary scale was created after adjusting the items and language with the help of patients and experts in the field. Next, 155 patients from 8 hospitals in different districts were recruited for a pilot survey using questionnaires containing these items. The patients’ responses were analyzed using the classical test theory and item response theory to select high-quality items and determine the subdomains of the scale. This was followed by a formal investigation in the same eight hospitals. In total, 360 patients and 100 healthy subjects were included to evaluate the reliability, validity, and feasibility of the items. Through this process, the final scale was established.ResultsThe final scale comprised 12 subdomains with 57 items related to physical, psychological, social, and therapeutic areas. The data analysis results of the formal investigation showed that the PROM for chronic heart failure had good reliability, validity, and feasibility. Reliability was verified by Cronbach’s alpha coefficient, which was 0.913 for the total scale, 0.903 for the physical domain, 0.941 for the psychological domain, 0.827 for the social domain, and 0.839 for the therapeutic domain. The construct validity results met the relative criteria of confirmatory factor analysis. Discriminant validity was represented by score comparisons of nine subdomains. The response rate and the effective rate of return of the CHF-PROM were 98.94% and 98.92%, respectively.ConclusionsThe final scale coincides with the theoretical framework and better reflects the overall quality of life of patients with chronic heart failure. This scale can be used as a valid instrument to evaluate clinical treatment and clinical trials of chronic heart failure.Electronic supplementary materialThe online version of this article (10.1186/s12955-018-0874-2) contains supplementary material, which is available to authorized users.

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Persian Version of Functional Assessment of Cancer Therapy- Breast (FACT-B) Scale: Confirmatory Factor Analysis and Psychometric Properties

Cited by 26 publications

References 17 publications

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

Bc-Prom

CHF-PROM: validation of a patient-reported outcome measure for patients with chronic heart failure

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