Permanent molar pulpotomy with a new endodontic cement: A case series

Asgary, Saeed; Ehsani, Sara

doi:10.4103/0972-0707.53340

Cited by 76 publications

(86 citation statements)

References 27 publications

(52 reference statements)

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“…Biochemical assays that evaluate the effects of dental materials on genetic tissues are relevant for minimizing risks to patients and clinicians. Antibacterial activity, cytotoxicity, clinical applications, and subcutaneous tissue reactions of CEM have been evaluated in several studies [24][25][26][27][28][29][30] . To our knowledge, however, this is the first study in which the genotoxic effects of CEM have been demonstrated in vitro by a single-cell gel electrophoresis (comet) assay.…”

Section: Discussionmentioning

confidence: 99%

Genotoxicity and cytotoxicity of mineral trioxide aggregate and calcium enriched mixture cements on L929 mouse fibroblast cells

et al. 2014

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Mineral trioxide aggregate (MTA) has shown good biocompatibility in several studies. In the present study, the genotoxic and cytotoxic effects of calcium enriched mixture (CEM) were evaluated compared with MTA using MTT and single-cell gel (comet) assays with serial ascending concentrations (0 to 1,000 µg/mL) of tested materials. Cytotoxicity data indicated that there is no significant difference between CEM and MTA at all concentrations except for the full concentration (1,000 µg/mL); CEM had lower cytotoxicity. Genotoxic effects were more evident with CEM at concentrations of 15.6 and 250 µg/mL; however, was less than that of MTA at concentrations of 500 and 1,000 µg/mL. The cytotoxicity and genotoxicity effects of the two experimental groups generally increased with consistency. Under the conditions of this study, CEM is biocompatible in terms of cyto-and genotoxicity. It appears to be an alternative to MTA as an endodontic biomaterial offering several advantages.

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Section: Discussionmentioning

confidence: 99%

Genotoxicity and cytotoxicity of mineral trioxide aggregate and calcium enriched mixture cements on L929 mouse fibroblast cells

et al. 2014

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“…3,14,16,25,26 However, the treatment technique in these studies is full pulpotomy, which often causes negative response to pulp vitality tests in follow-up sessions. By saving coronal pulp in the DPC technique, the clinician has the opportunity to perform pulp vitality tests in addition to periapical and radiographic examinations and to compare them with the baseline data and draw a distinct conclusion about pulp status.…”

Section: Discussionmentioning

confidence: 99%

“…Biological responses (the quality of dentinal bridges and the amount of pulp inflammation) after DPC with CEM cement and MTA were similar and better than CH in dogs' teeth. 13 CEM cement has been used successfully in pulpotomy of inflamed mature 14 and immature 15,16 human teeth. Two recent histological studies on DPC of healthy human teeth demonstrate similar biological responses to CEM cement and MTA.…”

Section: Introductionmentioning

confidence: 99%

Periapical Healing After Direct Pulp Capping With Calcium-enriched Mixture Cement: A Case Report

Asgary

Nosrat

Homayounfar

2012

Operative Dentistry

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SUMMARY This article describes a successful direct pulp capping of a mature symptomatic mandibular second molar in a 14-year-old girl. The patient was referred with sensitivity to cold beverages and pain on chewing on the second left mandibular molar. Clinical examinations revealed extensive coronal caries and sensitivity to percussion. Radiographically, the tooth was mature and had a widened apical periodontal ligament (PDL) and a narrow periapical lesion. The concluding diagnosis was symptomatic irreversible pulpitis with symptomatic apical periodontitis. Treatment included caries removal under rubber dam isolation, capping of exposure sites with calcium-enriched mixture (CEM) cement, and permanent coronal restoration. At three-, 10-, and 15-month follow-up, the tooth was functional, had normal response to cold test, and did not have sensitivity to percussion. The PDL space regained its normal width, and the periapical lesion healed.

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“…It is considered as the foundation of experimental research. It can contribute to medical science in two ways; as a source of new knowledge and in medical education and audit 6,8,47,56,[60][61][62][63][64] . Useful information and evidences also can be synthesized by doing meta-analysis of case reports 7 .…”

Section: Case Report As a Foundation Of Researchmentioning

confidence: 99%

An Overview of Reports on Clinical Case Report

Khan

Arif

2017

Anwer Khan Mod Med Coll J

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Case reports are the foundational 'building blocks' of scientific inquiry 7 . Many original observations were first presented as case reports. The discovery of AIDS was founded on the basis of a case report on extensively disseminated Kaposi's sarcoma in a young homosexual man published in the American Journal of Dermato-pathology in 19813.Unfortunatelyfrom late 1970sin scientific community there was a tendency to see the case report as least important and a 'second class' publication 1,8 . In Bangladesh and probably most of the peer reviewed journal all over the world; case reports are published in a separate section, not in the 'original article' sections. The authors tried to find out why a case report was not valued as an original publication or an important source of information in scientific progress. How they are valued in the scientific community was also an inspiring quarry. This article probably will help to focus on the way to answer the questions. IntroductionCase reports represent the oldest and most familiar form of medical communication 1 . Case descriptions suggestive of cancers were found in papyrus records in Egypt; as early as 1600 BC 2 . Even before Hippocrates case reports have provided a rich resource for teaching and research in medicine 3 . Sir William Osler encouraged others to record and publish whenever they have made or recorded unusual or original observation 4 . It is one of the best ways for beginners to get familiar with scholarly writing 5 . A case report may not have as much potential impact on the science or practice of health care as randomized controlled trial or other research results. However, it may be the only way to make others in the field aware of unusual presentations or complications. Most importantly it is the timehonored vehicle for teaching others. New syndromes, manifestations, associations, complications, or outcomes are appropriate subjects for case reports, as are typical well-documented examples of known entities that are relevant to a journal's readers 6 .AKMMC J 2016; 7(1): 50-55 REVIEW ARTICLECase reports represent the oldest and most familiar form of medical communication. It is one of the best ways for the beginners to get familiar with scholarly writing. It is the time-honored vehicle for medical teaching. It is also the foundational 'building block' of scientific inquiry. Unfortunately from late 1970s in scientific community there was a tendency to see the case report as least important and a 'second class' publication. The authors tried to find out how this 'fertile seeds' were cultivated and valued by the scientific community. Articles on case reports were collected consecutively by daisy chaining from web and published journals. Many logical arguments are found in favor of encouraging in writing and publishing case reports. There are also issues to be addressed further. Diversified criteria and stylescan be followed. Uniqueness is not the only principle, any information which someone find useful and beneficial in clinical practice can be presented a...

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Permanent molar pulpotomy with a new endodontic cement: A case series

Cited by 76 publications

References 27 publications

Genotoxicity and cytotoxicity of mineral trioxide aggregate and calcium enriched mixture cements on L929 mouse fibroblast cells

Genotoxicity and cytotoxicity of mineral trioxide aggregate and calcium enriched mixture cements on L929 mouse fibroblast cells

Periapical Healing After Direct Pulp Capping With Calcium-enriched Mixture Cement: A Case Report

An Overview of Reports on Clinical Case Report

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