Periviscerokinin (Pea-PVK): A novel myotropic neuropeptide from the perisympathetic organs of the American cockroach

Predel, Reinhard; Linde, Dirk; Rapus, Jürgen; Vettermann, Stefan; Penzlin, Heinz

doi:10.1016/0196-9781(94)00144-u

Cited by 58 publications

(21 citation statements)

References 12 publications

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“…Similarly, the chromatographic quantification and characterization of neuropeptide F (NPF) in molluscs (Leung et al, 1994;Santama et al, 1994), SCP B -like cardioactive peptide in Aplysia (Morris et al, 1982) and HPLC identification of APGWamide-related peptides in molluscs (Henry et al, 2000) are all consistent with our HPLC/UV analysis. Also, previous HPLC studies in non-molluscan invertebrates, such as coelenterates (Grimmelikhuijzen et al, 1988), annelids (Porchet and Dhainaut-Courtois, 1988) and arthropods (Bungart et al, 1995;Predel et al, 1995;Yi et al, 1995) all support our findings.…”

Section: Discussionsupporting

confidence: 87%

Identification of peptide-like substances in the Placopecten: Possible role in growth and reproduction

Pani¹,

Roghani²,

Croll³

2005

Biogenic Amines

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1. We have separated and quantified six putative peptide-like substances from the central nervous system (CNS), heamolymph, and gonads of the deep-sea scallop Placopecten magellanicus using high performance liquid chromatography with ultraviolet detection (HPLC-UV). 2. These peptide-like substances are tentatively identified as APGWamide, YFMRFamide, FMRFamide, nLRFamide, MNYLAFPRMamide and EDPFLRFamide. 3. All six peptide-like substances are co-eluted with known external peptide standards. Two of these compounds, APGWamide and FMRFaminde, are also confirmed for their identity by dot immunobinding assay (DIA). 4. The relative abundance of these peptide-like substances in the scallop is as follows: ganglia, greater than haemolymph, greater than gonads. 5. These compounds may be involved in growth and reproduction as demonstrated by their relative changes in HPLC-UV detected peak heights after thermal shockinduced spawning in the scallop.

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Section: Discussionsupporting

confidence: 87%

Identification of peptide-like substances in the Placopecten: Possible role in growth and reproduction

Pani¹,

Roghani²,

Croll³

2005

Biogenic Amines

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“…Having isolated myotropic peptides from an extract of 1,000 abdominal PSOs, from which Pea-PVK-1 and -2 (Predel et al, 1995 and Pea-PK-5 (Predel et al, 1999a) were identified, we assumed that these neurohaemal organs contain a neuropeptide pattern totally different from that of the brain. To confirm this assumption, we purified and identified the other abundant neuropeptides from these organs (Predel et al, 1999c).…”

Section: Isolation Of Pea-pk-6 From Abdominal Psosmentioning

confidence: 99%

Tagma-specific distribution of FXPRLamides in the nervous system of the American cockroach

Predel

Eckert

2000

J. Comp. Neurol.

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“…40 Related peptides were isolated from the perisympathetic organs of six different cockroach species. 41,42 These so-called periviscerokinins display a myotropic effect on the hyperneural muscle of Periplaneta americana. No information is available on possible effects on Malpighian tubule secretion in these insects.…”

Section: The Cardio Acceleratory Peptide or Capability Precursormentioning

confidence: 99%

Peptidomic analysis of the larval Drosophila melanogaster central nervous system by two‐dimensional capillary liquid chromatography quadrupole time‐of‐flight mass spectrometry

et al. 2005

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Peptides are the largest class of signalling molecules found in animals. Nevertheless, in most proteomic studies peptides are overlooked since they literally fall through the mazes of the net. In analogy with proteomics technology, where all proteins expressed in a cell or tissue are analyzed, the peptidomic approach aims at the simultaneous visualization and identification of the whole peptidome of a cell or tissue, i.e. all expressed peptides with their post-translational modifications. In this paper we describe the analysis of the larval fruit fly central nervous system using two-dimensional capillary liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (LC/Q-TOF-MS/MS. Using the central nervous systems of only 50 larval Drosophila as starting material, we identified 38 peptides in a single analysis, 20 of which were not detected in a previous study that reported on the one-dimensional capillary LC/MS/MS analysis of the same tissue. Among the 38 sequenced peptides, some originate from precursors, such as the tachykinin and the IFamide precursor that were entirely missed in the first study. This clearly demonstrates that the two-dimensional capillary LC approach enhances the coverage of the peptidomic analysis.

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Periviscerokinin (Pea-PVK): A novel myotropic neuropeptide from the perisympathetic organs of the American cockroach

Cited by 58 publications

References 12 publications

Identification of peptide-like substances in the Placopecten: Possible role in growth and reproduction

Identification of peptide-like substances in the Placopecten: Possible role in growth and reproduction

Tagma-specific distribution of FXPRLamides in the nervous system of the American cockroach

Peptidomic analysis of the larval Drosophila melanogaster central nervous system by two‐dimensional capillary liquid chromatography quadrupole time‐of‐flight mass spectrometry

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