Perivascular epithelioid cell neoplasm (PEComa) of the uterus: A systematic review

Abstract

Although the optimal treatment of gynecological PEComas is controversial, surgical resection remains the cornerstone. The use of adjuvant treatment is warranted in high risk patients to increase disease control. A multidisciplinary approach should be key in treatment decision-making regarding gynecological PEComas.

Perivascular epithelioid cell tumor of the uterus: Report of two cases and mini-review of the literature

“…Moreover, these cells are characterized immunoreactive for melanocytic markers, with an epithelioid appearance and a clearacidophilic cytoplasm, thus the term “perivascular epithelioid” was introduced [2] . Progressively, this family of tumors came to include angiomyolipoma, clear cell sugar tumors, lymphangioleiomyomatosis, clear cell myomelanocytic tumor of the falciform ligament and other clear cell tumors [3] . According to World Health Oraganization (WHO), PEComas are now defined as mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells [4] .…”

Labia majora labioplasty in a morbid obese patient affected by vulvar cancer involving urethra: a case report

“…Moreover in obese patients the labia majora volume contributes to mechanical urethral obstruction (18). Hence by reducing the volume of labia majora, we have attempted to decrease the risk of urethral obstruction and urinary flow dysfunctions.…”

Remote Radiotherapy in the Treatment of Patients with Perivascular Epithelial Cell Tumors

“…Отдельные публикуемые случаи [15] не дают чёткого представления о преимуществах и недостатках такого комбинированного подхода по сравнению с только хирургическим. При этом ряд авторов полагает оправданным проведение адъювантного лечения, в том числе лучевой терапии как одного из вариантов, у пациентов с определёнными клиническими ситуациями, например, у пациенток с ПЭКомой тела матки высокого риска [16].…”