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Although systematic pelvic lymphadenectomy statistically significantly improved surgical staging, it did not improve disease-free or overall survival.

Systematic lymphadenectomy improves progression-free but not overall survival in women with optimally debulked advanced ovarian carcinoma.

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Sumnuary High levels of IL-6 were found in 50% of 114 patients with pnrmary ovarian cancer. IL-6 sensitivity was lower than that of CA 125. and the combination of both assays did not increase the sensitivity of CA 125 alone. However, elevated IL-6 serum levels were correlated with a poor prognosis since patients with low IL-6 levels had a better survival than patients with high IL-6 levels (P = 0.0009). Multivariate analysis revealed that IL-6 positivity has an independent value.

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No external funding was sought or obtained for this study. No conflicts of interest are declared.