Peritonitis Caused by Veillonella Species and Eggerthella lenta in Peritoneal Dialysis

Goupil, Rémi; Nadeau‐Fredette, Annie‐Claire; Tennankore, Karthik; Bargman, Joanne M.

doi:10.3747/pdi.2013.00046

Cited by 9 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent reports have shown that several E. lenta infections were associated with the use of intrauterine devices, spondylodiscitis, female genital tract infections, cutaneous abscesses, and bacteremia (in Crohn's disease patients) [1][2][3][4]12]. These data emphasize the importance of further investigation for bacterial virulence factors.…”

Section: Discussionmentioning

confidence: 89%

See 1 more Smart Citation

Bacteremia Caused byEggerthella lentain an Elderly Patient with an Intra-abdominal Abscess

Eom

Kim

et al. 2016

Lab Med Online

View full text Add to dashboard Cite

A 73-yr-old male presented with fever, vomiting, and dyspnea.His medical history included a prior cerebrovascular attack and multiple complications caused by hemiplegia, including recurrent urinary tract infections and pressure sores requiring continuous medical care.On the day of admission, his body temperature, pulse rate, respiratory rate, and blood pressure were 40.4°C, 108/min, 39/min, and 170/90 mmHg, respectively. Abdominal examina-tion revealed diffuse tenderness and guarding with absence of bowel sounds. The initial laboratory test data were as follows: Hb, 14.9 g/dL; white blood cell count, 7,250/μL (neutrophils, 78.0%); and platelets, 110,000/μL. His procalcitonin level was elevated to 28.46 ng/mL. Sputum and urine cultures were negative. PCR to detect Eggerthella lenta is an anaerobic, non-spore-forming, non-motile, gram-positive bacillus that can be isolated from human feces and a few other clinical specimens. Bacteremia caused by the organism is rare but, when present, is always of clinical significance. E. lenta is an emerging pathogen that has been under-recognized because of difficulties with its laboratory identification. Few reports on E. lenta infections and the optimal treatment thereof are available. We describe a case of bacteremia caused by E. lenta in an elderly patient with an intra-abdominal abscess. We also review the current literature.

show abstract

Section: Discussionmentioning

confidence: 89%

“…Predisposing conditions include gastrointestinal tract disease, malignancies, hepatobiliary disease, immobilization, bedsores, diabetes mellitus, and stroke [2][3][4]. E. lenta is an emerging pathogen that has been under-recognized because of difficulties with its laboratory identification [3].…”

Section: Introductionmentioning

confidence: 99%

Bacteremia Caused byEggerthella lentain an Elderly Patient with an Intra-abdominal Abscess

Eom

Kim

et al. 2016

Lab Med Online

View full text Add to dashboard Cite

show abstract

“…A similar case was reported by Nebel (30). Later reports confirmed the value of temporary discontinuation of PD without catheter removal in treating refractory EM peritonitis (31,32), even in a case of perforated appendicitis (33).…”

Section: Discussionmentioning

confidence: 93%

Improved Outcome of Enteric Peritonitis in Peritoneal Dialysis Patients Aged 50 Years and Older with Temporary Discontinuation of Peritoneal Dialysis and Intravenous Meropenem

et al. 2017

View full text Add to dashboard Cite

♦ BACKGROUND: Peritonitis is a major cause of morbidity, mortality, and technique failure in peritoneal dialysis (PD) patients, especially when caused by enteric microorganisms (EM). We have implemented a treatment protocol specifically aimed at improving the outcome in EM peritonitis. The adapted protocol was applied in all PD patients 50 years and older presenting with peritonitis who were considered to be at risk of EM peritonitis and involves 3 interventions: 1) temporary discontinuation of PD without removing the catheter (peritoneal rest), 2) intravenous meropenem, and 3) meropenem intracatheter as lock (Mero-PerRest protocol). ♦ METHODS: In this observational study, we compared the outcome of 203 peritonitis episodes in 71 patients treated with the Mero-PerRest protocol, with 217 episodes in 104 patients treated with a more traditional intraperitoneal gentamicin-rifampicin-based regimen. ♦ RESULTS: In EM peritonitis episodes, the Mero-PerRest protocol resulted in a higher primary cure rate (90.0% vs 65.3%, adjusted odds ratio [OR] 4.54 [95% confidence interval (CI) 1.46 - 14.15]) and better technique survival (90.0% vs 69.4%, adjusted OR 3.41 [95% CI 1.07 - 10.87]). This effect was most distinct in patients with polymicrobial EM peritonitis (cure rate 87.5% vs 34.8%, = 0.0003). Interestingly, primary cure rate (95.6% vs 84.7%, adjusted OR 3.92 [95% CI 1.37 - 11.19]) and technique survival (95.6% vs 85.6%, adjusted OR 3.60 [95% CI 1.25 - 10.32]) were also excellent in non-EM peritonitis episodes. Patient survival did not differ significantly. ♦ CONCLUSION: The poor outcome of peritonitis caused by EM in PD patients aged 50 years and older could be improved by applying a treatment protocol involving temporary discontinuation of PD without catheter removal and intravenous and intracatheter meropenem.

show abstract

“…We summarized 175 patients with E. lenta bacteremia from the literature [ 5 – 7 , 10 , 19 – 31 ], along with the case reported here. The clinical characteristics of these 176 cases in total are presented in Table 1 .…”

Section: Discussionmentioning

confidence: 99%

Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature

Jiang¹,

Jianfei²,

Wang³

et al. 2021

Eur J Med Res

View full text Add to dashboard Cite

Eggerthella lenta is a normal human microflora that is anaerobic, non-sporulating, and Gram positive. However, an increasing number of studies have shown that it could also be an important pathogen for humans, even causing life-threatening infection under certain conditions. However, understanding its pathogenic mechanism and treatment options still need to be improved; more clinical data are needed to explore it further. In this article, we report a case of ceftizoxime-cured E. lenta bacteremia and review the recent literature to provide more clinical data for the diagnosis of E. lenta bacteremia. Our report suggests that the frequency of E. lenta bacteremia is increased in patients with hematologic or solid organ cancer, diabetes mellitus and also in those with appendicitis.

show abstract

Peritonitis Caused by Veillonella Species and Eggerthella lenta in Peritoneal Dialysis

Cited by 9 publications

References 11 publications

Bacteremia Caused byEggerthella lentain an Elderly Patient with an Intra-abdominal Abscess

Bacteremia Caused byEggerthella lentain an Elderly Patient with an Intra-abdominal Abscess

Improved Outcome of Enteric Peritonitis in Peritoneal Dialysis Patients Aged 50 Years and Older with Temporary Discontinuation of Peritoneal Dialysis and Intravenous Meropenem

Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature

Contact Info

Product

Resources

About