Peritoneal Tuberculosis Mimicking Peritoneal Carcinomatosis

Мартынов, А. И.; Saleeb, Monica; Saleeb, Y.M.; Kerolos, Mina M; Zaki, Mark M.

doi:10.55320/mjz.45.3.149

Cited by 1 publication

(3 citation statements)

References 3 publications

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“…This disease accounts for 0.1-0.7% of all tuberculosis cases worldwide. 10 The most common clinical sign is ascites, but patients may also present with abdominal pain, night sweats, fever, and abdominal distention. 5 The patient presented with complaints of abdominal pain, cough and fever, but it wasn't enough to make the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…1 Prior studies have indicated that primary pulmonary tuberculosis on CXR imaging is only seen in 15-20% of patients with PTB. 10 The routine laboratory tests are hardly diagnostic. A positive tuberculin skin test can indicate reactivation of TB, but it is diagnostically insigni cant as a negative skin test may be seen in patients with histologically con rmed peritoneal TB.…”

Section: Discussionmentioning

confidence: 99%

“…1,4 Regardless of history or risk factors, a differential diagnosis of patients who present with abdominal pain, ascites, and elevated CA-125 should include peritoneal TB. 5,10 We describe a 71-year-old Vietnamese female on hydrocortisone for adrenal insu ciency and multiple comorbidities with abdominal pain, fever, cough and mild ascites that was found to have omental fat stranding of the anterior mesentery on CT imaging. This imaging nding was initially thought to be secondary to peritoneal carcinomatosis from the patient's history of ovarian cancer, but tissue biopsy of the omental fat stranding con rmed the diagnosis of peritoneal TB.…”

Section: Introductionmentioning

confidence: 99%

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A Rare Case of Peritoneal Tuberculosis Mimicking Peritoneal Carcinomatosis: The Ongoing Challenge

Flores

Dopp

Bhatt

et al. 2023

Preprint

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Tuberculosis (TB) is a serious infection that can involve any organ system and present in various forms. About one-third of the world’s population are carriers of latent TB. Although most cases are from a pulmonary origin, there is a rising prevalence of abdominal TB. Patients with pulmonary or extrapulmonary TB are treated similarly through the use of pharmacological therapy. Nonspecific clinical manifestations of TB have made it difficult for clinicians to diagnose. Peritoneal tuberculosis (PTB) is a serious concern as its symptoms overlap with that of many other chronic conditions, especially in those who are immunocompromised. The lack of highly sensitive and specific testing methods has made early intervention difficult, therefore a high index of suspicion is crucial in the progression of the disease. Here, we present a case of a 71-year-old female with a history of abdominal pain, fever, and weakness. Initial investigation with CT imaging revealed omental fat stranding that pointed towards peritoneal carcinomatosis (PC) from possible recurrence of her ovarian cancer. Further investigation with a peritoneal biopsy was remarkable for caseating granulomas with fat necrosis confirming extrapulmonary TB. This report highlights a rare case of PTB mimicking PC in an elderly patient who is immunocompromised from the use of long-term corticosteroids who continued to decline after pharmacological treatment of the disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%