Peritoneal fluid cytology associated with benign neoplastic ovarian tumors in women

McGowan, Larry; Bunnag, Bill; Arias, Luis B.

doi:10.1016/0002-9378(72)90665-5

Cited by 9 publications

(5 citation statements)

References 2 publications

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“…Although a few stage I ovarian cancers apparently shed cytologically abnormal cells into the pelvic peritoneal fluid (5,11,14,18,19), the pain of culdocentesis repels patients, the sharp point of the needle may easily lacerate the capsule of an intact adnexal cyst, immediately spreading its contents (35), and results of cul-de-sac cytology are usually inconclusive (9,14). Therefore, we do not favor culdocentesis to obtain peritoneal cytologic specimens.…”

Section: Discussionmentioning

confidence: 99%

Early Identification, Differentiation and Treatment of Ovarian Neoplasia

Ranney

Ahmad

1979

Intl J Gynecology & Obste

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Among 3205 patients who needed major gynecologic operations, only 250 (7.8%) had significant ovarian cysts or tumors (170 benign, 38 "low malignant potential," 42 gross cancers). Contrary to prior reports, this study show that most patients with ovarian neoplasia had had some symptoms (duration ranged from two weeks to ten years), or a palpable adnexal mass or both. Associated symptoms have been itemized in categories. Procrastination by patients, after occurrence of the first symptoms, resulted in the growth of later-stage cancers and lower survival rates. It may be inferred from age-incidence graphs that some benign cystadenomas may be present in ovaries for long intervals of time and then may become malignant. The importance of (a) careful recording of histories, (b) periodic pelvic examinations, (c) the use of preoperative methods of differential diagnosis and (d) the differentiation between gross tumor characteristics during operations are discussed. Earlier diagnosis and treatment of ovarian neoplasia are possible and will yield better long-term results.

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Section: Discussionmentioning

confidence: 99%

Early Identification, Differentiation and Treatment of Ovarian Neoplasia

Ranney

Ahmad

1979

Intl J Gynecology & Obste

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“…Benign cystic teratomas are associated with distinctive benign atypical cells of nonmesothelial origin. 5 Elongated cells with lengthened nuclei may be seen with mucinous cystadenoma, and a type of large cell noted with serous cystadenoma has been described in detail. 5 These are additional examples of benign atypical cells of nonmesothelial origin.…”

Section: Discussionmentioning

confidence: 99%

“…5 Elongated cells with lengthened nuclei may be seen with mucinous cystadenoma, and a type of large cell noted with serous cystadenoma has been described in detail. 5 These are additional examples of benign atypical cells of nonmesothelial origin. The presence of tall columnar cells, with or without cilia, in peritoneal fluid is compatible with a serous cystadenoma.…”

Section: Discussionmentioning

confidence: 99%

“…Another benign atypical cell category includes short columnar cells with or without cilia from a mucinous cystadenoma. 5 Proliferative germinal epithelial changes of the ovary as well as ovarian neoplasms of low potential malignancy may be found in the category of cells possessing nuclear characteristics suggestive of, but not conclusive for, malignancy. Some invasive cancers of the ovary, especially those in Stages la, lb, and Ic, also may be seen in the latter group.…”

Section: Discussionmentioning

confidence: 99%

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A Morphologic Classification of Peritoneal Fluid Cytology in Women

McGowan

Bunnag

1973

International Journal of Gynecology & Obstetrics

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THE STANDARDIZATION of technics and a large experience with both laboratory animals and women have permitted the formulation of a morphologic classification of peritoneal fluid cells in women. ' " ' 9 Since our first publication on the subject, our technic for obtaining the cytologic specimen as well as the technic for fixing, staining, and examining the material has remained unchanged. 19 The peritoneal fluid cellular samples were obtained by an established gynecologic outpatient diagnostic procedure, culdocentesis, or by direct aspiration at the time of operation. The specimen was immediately placed on an albumin-coated slide and then promptly fixed in 95% ethyl alcohol. The cytologic specimens were stained according to Papanicolaou's procedure. 20 The complete description of the procedure used in women to obtain the cytologic specimens has been previously described. 13 All of the cytologic specimens were examined microscopically under oil immersion.As our knowledge of peritoneal fluid cytology in women expands, we must have a meaningful classification to communicate to the practicing physician. We are aware of the many studies in the literature pertaining to peritoneal fluid in women; however, the marked variations in the methods of obtaining the specimens, fixing and staining them, and the varying procedures

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“…the finding of malignant cells may be the only positive evidence and may be crucial in the decision to use chenio-or radiotherapy. Free fluid from the pouch of Douglas is also used; it may be obtained at laparotomy or laparoscopy, or else by cul-de-sac puncture (McGowan et a/. 1972;Villa Santa & Jovanovski 1980;Jones et al 1981).…”

Section: O M M E N T a R Y Cytology Of Peritoneal Aspirates And Wasmentioning

confidence: 99%

Cytology of peritoneal aspirates and washings

Spriggs

1987

BJOG

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Peritoneal fluid cytology associated with benign neoplastic ovarian tumors in women

Cited by 9 publications

References 2 publications

Early Identification, Differentiation and Treatment of Ovarian Neoplasia

Early Identification, Differentiation and Treatment of Ovarian Neoplasia

A Morphologic Classification of Peritoneal Fluid Cytology in Women

Cytology of peritoneal aspirates and washings

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