Peripheral T-cell lymphoma: a challenging mimicker of angioedema and urticaria

Patel, Shreya; Patel, R. D.; Draikiwicz, Steven; Capitle, Eugenio

doi:10.1016/j.anai.2015.06.013

Cited by 6 publications

(10 citation statements)

References 8 publications

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“…Less than 1% of non-Hodgkin's lymphomas are panniculitis-like T-cell lymphomas. 39,40 It has no clear gender predilection and typically presents in patients aged 18-60 years. Clinical symptoms are variable but usually consist of multiple indurated, ill-defined subcutaneous nodules or plaques resembling panniculitis.…”

Section: Lymphoproliferative Disordersmentioning

confidence: 99%

“…Other authors have also reported facial swelling as a presenting feature of panniculitis-like T-cell lymphoma. 39,40 It is associated with a variety of autoimmune diseases in about 20% of patients and is often characterized by an aggressive clinical course in comparison with other cutaneous lymphomas. Anthralin-based chemotherapy is the most used regimen for panniculitis-like T-cell lymphoma.…”

Section: Lymphoproliferative Disordersmentioning

confidence: 99%

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If not angioedema, what is it? Diagnostic approach to facial edema

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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SummaryFacial edema is a relatively frequent clinical presentation encountered in patients seen in allergology and dermatology clinics. The differential diagnosis is broad, and sometimes the definitive diagnosis can be a challenge for the clinician. Facial angioedema itself encompasses different etiopathologies (histaminergic, bradykinergic, etc.) that must be distinguished from other causes of facial edema, such as allergic contact dermatitis, granulomatous conditions, inflammatory causes, infections, neoplasms or paraneoplastic syndromes, autoimmune diseases, among other entities hereby referred as miscellanea. A proper diagnostic approach is essential to order the appropriate tests, as well as to prescribe a targeted treatment. This review focuses on entities that present with facial edema and summarize their characteristic clinical features.

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Section: Lymphoproliferative Disordersmentioning

confidence: 99%

Section: Lymphoproliferative Disordersmentioning

confidence: 99%

If not angioedema, what is it? Diagnostic approach to facial edema

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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“…Weniger als 1% der Non-Hodgkin-Lymphome sind pannikulitisähnliche T-Zell-Lymphome. 39,40 Es gibt keine eindeutige Geschlechtsprädilektion und die Erkrankung tritt typischerweise bei Patienten im Alter von 18 bis 60 Jahren auf. Die klinischen Symptome sind variabel, aber in der Regel aus multiplen indurierten, schlecht definierten subkutanen Knötchen oder Plaques, die einer Pannikulitis ähneln.…”

Section: Lymphoproliferative Erkrankungenunclassified

Wenn es kein Angioödem ist, was dann? Diagnostisches Vorgehen bei Gesichtsödemen

Velasco‐Amador,

Prados‐Carmona,

Navarro‐Triviño

2024

J Deutsche Derma Gesell

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ZusammenfassungGesichtsödeme sind ein relativ häufiges Symptom bei Patienten allergologischer und dermatologischer Kliniken. Die Differentialdiagnose ist breit gefächert und die endgültige Diagnose kann manchmal eine Herausforderung für den Kliniker sein. Das faziale Angioödem selbst umfasst verschiedene Ätiopathologien (histaminerg, bradykinininduziert und weitere), die von anderen Ursachen des Gesichtsödems differenziert werden sollten, etwa allergischer Kontaktdermatitis, granulomatösen Erkrankungen, inflammatorischen Ursachen, Infektionen, Neoplasmen oder paraneoplastischen Syndromen, Autoimmunerkrankungen und anderen Entitäten, die hier als „Sonstige“ bezeichnet werden. Um die richtigen Untersuchungen anzuordnen und eine gezielte Therapie zu verordnen, ist ein angemessener diagnostischer Ansatz ausschlaggebend. Diese Übersicht konzentriert sich auf Entitäten, die mit Gesichtsödem einhergehen, und fasst ihre klinischen Charakteristika zusammen.

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“…Previously, a few rare cases of peripheral T-cell lymphoma presenting periorbital, upper and lower lip edema, initially mistaken for angioedema, are reported [44][45][46]. The clinical findings to differentiate from angioedema are progression and no resolution of these lesions.…”

Section: Lymphoproliferative Disordersmentioning

confidence: 99%

“…The clinical findings to differentiate from angioedema are progression and no resolution of these lesions. The final diagnosis is based on histopathologic examination [2,45,46].…”

Section: Lymphoproliferative Disordersmentioning

confidence: 99%

Pseudoangioedema

Akarsu¹,

Canturk²

2017

A Comprehensive Review of Urticaria and Angioedema

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Angioedema is a rapid, localized and temporary subcutaneous edema, which targets the lips, eyelids, gastrointestinal and respiratory mucosa resulting in abdominal pain, asthma and even serious life-threatening conditions like airway obstruction. There are several other disorders such as allergic contact dermatitis, drug rash with eosinophilia and systemic symptoms (DRESS), superior vena cava syndrome (SVCS), orofacial granulomatosis and so on, which manifest with subcutaneous swelling and masquerade as angioedema and are known as 'pseudoangioedema' in the literature. Knowledge of pseudoangioedema for healthcare professionals is crucial to avoid potentially serious results of misdiagnosis such as further investigations, unnecessary applications and delayed diagnosis. We aim to discuss differential diagnosis of angioedema and help physicians recognize the typical features of angioedema and its differential diagnosis in this chapter.

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Peripheral T-cell lymphoma: a challenging mimicker of angioedema and urticaria

Cited by 6 publications

References 8 publications

If not angioedema, what is it? Diagnostic approach to facial edema

If not angioedema, what is it? Diagnostic approach to facial edema

Wenn es kein Angioödem ist, was dann? Diagnostisches Vorgehen bei Gesichtsödemen

Pseudoangioedema

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