Peripheral intravenous alimentation of the small premature infant

Benda, Gerda I.; Babson, S. Gorham

doi:10.1016/s0022-3476(71)80165-8

Cited by 42 publications

(11 citation statements)

References 8 publications

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“…The early 1970s saw the beginning of the use of total parenteral nutrition (TPN) in very low birth weight (VLBW) infants with several studies being published by Driscoll [28], Benda [29] and others. Parenteral nutrition (continued on next page) (PN) was rapidly adopted over the existing glucose-only infusion as an alternate method for delivering nutrition to VLBW infants.…”

Section: Complications Of Parenteral Nutritionmentioning

confidence: 99%

Iatrogenic Disorders in Modern Neonatology: A Focus on Safety and Quality of Care

Ramachandrappa¹,

Jain²

2008

Clinics in Perinatology

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Section: Complications Of Parenteral Nutritionmentioning

confidence: 99%

Iatrogenic Disorders in Modern Neonatology: A Focus on Safety and Quality of Care

Ramachandrappa¹,

Jain²

2008

Clinics in Perinatology

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“…These investigators randomly as¬ signed neonates receiving parenteral lipid to one of three methods of fat emulsion infusion: (1) progressive daily increases in dosage (from 1 to 4 g/kg/d maximally with administration over 24 hours); (2) progressive advancement in daily dosage (1 to 4 g/kg/d) at a steady infusion rate over 16 hours, followed by a rest period of eight hours prior to initiation of the next day's infusion; and (3) initial use of maximal dosage (4 g/kg/d) at a steady rate over 24 hours. Plasma lipid patterns were closely monitored.…”

mentioning

confidence: 99%

Metabolic Tolerance of Parenteral Lipid in Neonates

Bedrick¹

1988

Am J Dis Child

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“…Partial parenteral nutrition as a supplement to inadequate oral intake has been used successfully in low birthweight infants (Benda and Babson, 1971;Cashore et al, 1975), although comparative studies Department of Paediatrics, Queen Victoria Medical Centre, Melbourne V. Y. H. YU, director of neonatal intensive care B. JAMES, professional officer P. HENDRY, technical officer R. A. MACMAHON, associate professor of parenteral supplementation versus conventional feeding regimens showed similar morbidity and mortality (Bryan et al, 1973;Pildes et al, 1973;Brans et al, 1974;Abitbol et al, 1975). The feasibility of supplying complete requirements with total parenteral nutrition (TPN) via centrally placed catheters has been reported (Driscoll et al, 1972;Peden and Karpel, 1972;MacMahon et al, 1975;Hall and Rhodes, 1976;Meng et al, 1977).…”

mentioning

confidence: 99%

Total parenteral nutrition in very low birthweight infants: A controlled trial

Yu¹,

James²,

Hendry³

et al. 1979

Archives of Disease in Childhood

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SUMMARY 34 preterm infants with birthweights < 1200 g were randomly assigned to total parenteral nutrition (TPN) or oral (Milk) feeding regimens for the first 2 weeks after birth. Infants in the TPN group were started on a modified Vamin-based glucose amino-acid infusion and Intralipid. The daily amounts of carbohydrate, amino-acids, and fat infusions were increased. In the Milk group, infants were started on intermittent gavage feeding, supplemented with a glucose-electrolyte infusion as necessary. The overall mortality rate did not differ in the two groups. Four infants in the Milk group developed necrotising enterocolitis but none did in the TPN group. Despite mean daily energy intakes which were not greatly different, there were much higher mean daily intakes of carbohydrate and protein in the TPN group compared with the Milk group. Fat intake in the TPN group was lower than in the Milk group in the 1st week because of neonatal jaundice which contraindicated the use of Intralipid. There was no difference in the mean daily fat intake by the 2nd week. Although mean daily weight loss in the 1st week and the maximum postnatal weight loss in the two groups were similar, infants in the TPN group had a greater mean daily weight gain in the 2nd week and took less time to regain and maintain birthweight. Metabolic complications were equally common in both groups and were reversible with early recognition. Limits of tolerance for water and most nutrients tended to be variable and the nutritional programme had to be adjusted for each baby. Nevertheless, we found that TPN, when properly managed, is an effective and safe procedure in very low birthweight infants.

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Peripheral intravenous alimentation of the small premature infant

Cited by 42 publications

References 8 publications

Iatrogenic Disorders in Modern Neonatology: A Focus on Safety and Quality of Care

Iatrogenic Disorders in Modern Neonatology: A Focus on Safety and Quality of Care

Metabolic Tolerance of Parenteral Lipid in Neonates

Total parenteral nutrition in very low birthweight infants: A controlled trial

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