Peripapillary Choroidal Neovascular Membrane Associated With an Optic Nerve Coloboma

Dailey, John R.; Cantore, William A.; Gardner, Thomas W.

doi:10.1001/archopht.1993.01090040031020

Cited by 23 publications

(8 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several authors have described peripapillary subreti nal neovascularization associated with true coloboma of the optic nerve [3,9,28]. In our case the subretinal net was totally separated from the border of the inferior dysplastic optic nerve staphyloma in the right eye.…”

Section: Discussionmentioning

confidence: 46%

Butterfly-shaped pigment dystrophy of the fovea associated with subretinal neovascularization

Marano

Deutman

Aandekerk

1996

Graefe's Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 46%

Butterfly-shaped pigment dystrophy of the fovea associated with subretinal neovascularization

Marano

Deutman

Aandekerk

1996

Graefe's Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

“…Laser photocoagulation is the most frequently used method reported in the literature and has consistently resulted in regression of the CNV and improvement of visual acuity in these cases. [242526272829] It is generally avoided in cases of juxtafoveal or subfoveal CNV due to the high risk of iatrogenic vision loss.…”

Section: Discussionmentioning

confidence: 99%

Chorioretinal coloboma complications: retinal detachment and choroidal neovascular membrane

Hussain

Abbey

Shah

et al. 2017

J Ophthalmic Vis Res

View full text Add to dashboard Cite

Purpose:To report the chorioretinal coloboma, and its association with increased risk of retinal detachment (RD) and choroidal neovascularization (CNV).Methods:This retrospective case series included eyes with chorioretinal coloboma diagnosed between 1995 and 2014 with a focus on RD and CNV as related complications. Cases of CNV were managed with laser photocoagulation or intravitreal injection of bevacizumab. For eyes with CNV, therapeutic success was defined as resolution of the subretinal hemorrhage on fundus examination and resolution of the subretinal and intraretinal fluid on optical coherence tomography (OCT). For eyes with RD, anatomic success following surgical intervention was defined as attachment of the retina at the last follow-up visit.Results:Fifty-one eyes of 31 patients with chorioretinal coloboma were identified for review. Bilateral chorioretinal coloboma was present in 64.5% of subjects. RD developed in 15 eyes (29.4%). Among 15 eyes with RD, 4 eyes (27%) had retinal breaks identified within the coloboma, 5 eyes (33%) had retinal breaks outside the coloboma, 2 eyes (13%) showed retinal breaks both inside and outside the coloboma, and in 4 eyes (27%) the causative retinal break was not localized. The overall rate of anatomic success after RD repair was 85.7%. CNV developed in 7 eyes (13.7%) and was located along the margin of the coloboma in all cases. CNV was bilateral in 2 of the 5 affected individuals (40%).Conclusion:RD and CNV were present in a high percentage of eyes with chorioretinal coloboma in these series. The frequent finding of retinal breaks outside the coloboma bed suggests that vitreoretinal interface abnormalities may play a role in development of RD in these eyes.

show abstract

“…22 23 Rarely, chorioretinal colobomata give rise to subretinal neovascularisation, 24 especially if involving the optic nerve head. [25][26][27] Optic nerve The severity of optic disc involvement varies from no involvement to an obviously enlarged optic cup to gross anomaly ( fig 1D) unrecognisable as an optic nerve head. 28 Visual deficit attributable to optic nerve head coloboma correlates with the severity of this anomaly.…”

Section: Iris Colobomamentioning

confidence: 99%

Ocular coloboma: a reassessment in the age of molecular neuroscience

Gregory-Evans

Williams²,

Halford³

et al. 2004

Journal of Medical Genetics

215

194

View full text Add to dashboard Cite

Peripapillary Choroidal Neovascular Membrane Associated With an Optic Nerve Coloboma

Cited by 23 publications

References 2 publications

Butterfly-shaped pigment dystrophy of the fovea associated with subretinal neovascularization

Butterfly-shaped pigment dystrophy of the fovea associated with subretinal neovascularization

Chorioretinal coloboma complications: retinal detachment and choroidal neovascular membrane

Ocular coloboma: a reassessment in the age of molecular neuroscience

Contact Info

Product

Resources

About