Periorificial dermatitis in children: an update and description of a child with striking features

Abstract

Perioral dermatitis is more suitably termed periorificial dermatitis.

Pediatric Periorificial Dermatitis: Clinical Course and Treatment Outcomes in 222 Patients

“…The etiology for POD is considered to be idiopathic, but many studies correlate the use of a potent topical corticosteroid with the onset of POD symptoms, with greater potency linking to greater severity of the disease . Of interest is the correlation between the availability of potent topical corticosteroids and the appearance of POD in the 1950s .…”

“…Histologic examination is rarely performed but displays epithelioid cells and lymphohistiocytic infiltrate with occasional giant cells, indistinguishable from rosacea (6). The etiology for POD is considered to be idiopathic, but many studies correlate the use of a potent topical corticosteroid with the onset of POD symptoms, with greater potency linking to greater severity of the disease (1,2,(5)(6)(7)(8)(9)(10)(11)(12)(13). Of interest is the correlation between the availability of potent topical corticosteroids and the appearance of POD in the 1950s (8).…”

Phenotypes of atopic dermatitis

“…It may also develop as a superimposed condition in the presence of other anogenital diseases and frequently persists as an itch‐scratch cycle. For this reason, successful therapy requires attention not only to trigger factors, but also to repair of the damaged barrier layer, reduction in inflammation, and breakup of the itch‐scratch cycle [49, 50].…”

Involvement of the vermillion border in a severe case of periorificial dermatitis

“…In general, the vermillion border of the lips is spared,1–3 but it may become involved in severe cases (figure 1). 4 Comedones are also absent 1 3. The rash is often misdiagnosed as impetigo, acne vulgaris, contact dermatitis, atopic dermatitis, seborrheic dermatitis, dermatophyte infection or angiofibromas 3.…”