Periorbital Contact Sensitization

Is a specific eyelid patch test series useful? Results of a French prospective study

“…The high proportion of women in our study (90%) is similar to the percentage (70‐90%) reported in previous studies in other countries . It is higher than the 70% proportion of females in French patients patch tested for eczema with various localizations .…”

Metal allergy in eyelid dermatitis and the evaluation of metal contents in eye shadows

“…Sensitization rates to cobalt chloride and potassium dichromate were the same 7.5% in eyelid group. In recent studies of Europe and USA, the prevalence of cobalt sensitization was 4.5–8.6% and the prevalence of chromium allergy was 1.4–3.4% in patients with eyelid dermatitis . The high rates of sensitization to cobalt and chromium in this study may represent the general high prevalence of metal allergy in Korea…”

“…The prevalence of nickel allergy in Korea is high, ranging from 27.1% to 34.1% among patch tested patients . Moreover, nickel is the leading allergen in patients with eyelid/periorbital dermatitis in previous literature, with the reported frequency of 13–19.5% in Germany and USA . In this study, the frequency of nickel sensitization was 19.4% in eyelid group and 9.1% in eyelid only group.…”

“…Among the total patch test population, 6.8% of subjects had suspected contact allergy in eyelids. The reported prevalence of periorbital/eyelid dermatitis from other patch test clinics in the literature shows a wide variation, ranging between 2.1% and 21.3% …”

Topical ophthalmic agents as allergens in periorbital dermatitis

“…Patients patch tested to the ophthalmic tray made up only 24% of all referrals with periorbital dermatitis. Because of the more common application of cosmetics and topical products to the face, and especially to the periorbital area in females, periorbital dermatitis in general is predominated by female gender 3 10 11. Patients of the periorbital group were also significantly older when compared with the controls, most likely due to an increased use of ophthalmic products in older age groups.…”