Perioperative indicators of hypocalcemia in total thyroidectomy: the role of vitamin D and parathyroid hormone

Salinger, Eric M.; Moore, John T.

doi:10.1016/j.amjsurg.2013.08.020

Cited by 40 publications

(35 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3,8 Improvements in surgical technique have significantly decreased the complications associated total thyroidectomy. Despite it, postoperative hypocalcemia is still regarded as frequently encountered complication presenting as Tetany in the postoperative period.…”

Section: Discussionmentioning

confidence: 99%

“…Noticeable risk factors of hypocalcemia following thyroid surgery include; large goiters, recurrent goiter, retrosternal goiter extension, hyperthyroidism, total thyroidectomy and experience of the surgeons. 7,8 The present study was intended to find out the frequency of Hypocalcemia in patients operated for malignant thyroid surgery. It includes risk associated with the extent of surgery & severity of Hypocalcemia.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Malignant Thyroid Disease; Hypocalcaemia Following Thyroid Surgery

Talpur¹

2017

TPMJ

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Malignant Thyroid Disease; Hypocalcaemia Following Thyroid Surgery

Talpur¹

2017

TPMJ

View full text Add to dashboard Cite

“…'nın yaptığı prospektif analizde total veya tamamlayıcı tiroidektomi yapılan 111 hastada ameliyat öncesi D vitamini ve ameliyat sonrası PTH değerleri karşılaştırılmıştır. Ameliyat sonrası hipokalsemi açısından risk faktörlerini araştıran bu çalışmada erken yaş ve tiroidektomi sonrası PTH düşüklüğü risk faktörleri olarak belirlenmiş, D vitamini düzeyi ile hipokalsemi arasında anlamlı ilişki tespit edilmemiştir (19). Literatürdeki D vitamini düzeyi ile hipokalsemi arasındaki ilişkiyi inceleyen çok çeşitli çalışmalar mevcuttur (15,16,17,22).…”

Section: Bulgular Preoperatif Bulgularunclassified

D Vi̇tami̇ni̇ Düzeyi̇ni̇n Total Ti̇roi̇dektomi̇ Sonrasi Hi̇pokalsemi̇ Ri̇ski̇ Üzeri̇ne Etki̇si̇

Sormaz¹,

Meric²,

İşcan³

et al. 2016

İst Tıp Fak D

View full text Add to dashboard Cite

Material-Method:The records of 89 consecutive patients who underwent total thyroidectomy were retrospectively analyzed. Patients were divided into 2 groups according to preoperative vitamin D levels. In group 1(n = 63) preoperative 25-OH vitamin D level is ≤20 ng/ml, in group 2 (n=26) preoperative 25-OH vitamin D level is >20 ng/ml. Groups were compared according to their age, preoperative and postoperative corrected calcium and PTH levels. Results: The mean age was 47.8±14.1 and female/male ratio was 70/19 (3.68 / 1) in the whole group of patients. The mean preoperative PTH values was 54.8±22.6 pg/mL and the mean postoperative PTH value was 30±19 pg/ml. Postoperatively PTH and calcium levels were significantly lower than preoperative PTH and calcium levels. The demographic data showed no significant difference between two groups. The mean vitamin D level in group 1 and 2 were found 11.1±4 ng / ml and 30.6±10.4 ng / mL; respectively. Although the preoperative serum PTH levels showed statistically significant difference between the two, all were found in normal ranges. Postoperative 1 st day PTH levels were similar in two groups. Postoperative corrected calcium values showed no significant difference between group 1 and 2. Conclusion: Though vitamin D deficiency is a common entity in patients undergoing total thyroidectomy, this present study failed to show any relation between preoperative vitamin D levels and postperative hypocalcemia.

show abstract

“…However, the progressive increase in serum calcium values between 6 and 24 hours after surgery, and the finding of normal postsurgical calcium levels, have a high NPV (80%-100%) ruling out the possibility of permanent hypocalcemia and hypoparathyroidism [13,19,31,45,51]. c) 25-Hydroxi-vitamin D 3 levels: Low levels of VD increase the probability of hypocalcemia in the postsurgical period [30,33].…”

Section: B) Serum Calcium Valuesmentioning

confidence: 99%

“…Postsurgical hypoparathyroidism has been defined as the presence of serum levels of iPTH below 15 pg/mL in the postoperative period [11][12][13], in the presence of CSC values < 8.0 mg/dL (2.0mmol/L), or ionized calcium below 1.1 mmol/L (4.4 mg/dL) with or without symptoms of hipocalcemia [11,[13][14][15][16][17][18][19][20].…”

Section: Post-surgical Hypoparathyroidism In Thyroid Surgerymentioning

confidence: 99%