Perioperative diagnosis of the positive axilla in breast cancer: A safe, time efficient algorithm

Abstract

This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Title:Perioperative diagnosis of the positive axilla in breast cancer: A safe, time efficient algorithm.Background: This study evaluates the combined role of axillary ultrasound (Ax US), fine needle aspiration (FNAC) and intraoperative frozen section analysis of the sentinel node (FS SN) in a practical, time efficient algorithm to reduce the requirement for reoperation for axillary clearance in breast cancer in a busy tertiary unit. Methods

Diagnostic Accuracy of Ultrasonograph Guided Fine-needle Aspiration Cytologic in Staging of Axillary Lymph Node Metastasis in Breast Cancer Patients: a Meta-analysis

“…Consequently, 44 articles included information relating FNAC and breast cancer diagnosis. But only 21 of 44 articles satisfied the requirements of the meta-analysis fully (Bonnema et al, 1997;Bedrosian et al, 2003;Deurloo et al, 2003;Kuenen-Boumeester et al, 2003;Sapino et al, 2003;Duchesne et al, 2005;Podkrajsek et al, 2005;Popli et al, 2006;van Rijk et al, 2006;Altomare et al, 2007;Ciatto et al, 2007;Alkuwari et al, 2008;Tahir et al, 2008;Baruah et al, 2010;Jung et al, 2010;Luparia et al, 2010;Carroll et al, 2011;Devaraj et al, 2011;Hayes et al, 2011;Schiettecatte et al, 2011), addressing the value of FNAC in staging of axillary lymph node in breast cancer patients. The detailed procedure was seen in Figure 1.…”

The Z0011 Trial: Is this the end of axillary ultrasound in the pre-operative assessment of breast cancer patients?

“…The Z0011 study population was noted to have a low axillary nodal burden in comparison to a number of recent studies [13,14]. The study also had a short follow-up period with a median follow-up of 6.3 years.…”

Role of Axillary Ultrasound, Fine Needle Aspiration Cytology and Sentinel Lymph Node Biopsy in clinically N0 Breast Cancer

“…Overall, only 8 women required reoperation for axillary clearance. Sensitivity for the combined procedures was 91.4 % [15]. In Our study 52 patients had positive axillae at final histology.…”

“…Surgeon can thereby perform ALND at the time of primary breast surgery in FNAC and frozen positive cases [15]. Advantage of above combination is we can directly plan definitive surgery, reduces operating time and cost effective as SLNB can be omitted in FNAC positive cases.…”