Perioperative Anämietoleranz

Häbler, O.; Meier, Jens; Pape, Andreas; Kertscho, H.; Zwißler, Bernhard

doi:10.1007/s00101-006-1055-y

Cited by 25 publications

(9 citation statements)

References 119 publications

(59 reference statements)

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“…A drop in Hb and, as a consequence, the reduced oxygen transport capacity put a high demand on the cardiovascular system and on the coronary reserve [42]. Therefore, it appears to be only logical to treat cardiac risk factors preoperatively.…”

Section: Increase and Use Of Individual Tolerance To Anemiamentioning

confidence: 99%

Patient Blood Management: A Patient-Orientated Approach to Blood Replacement with the Goal of Reducing Anemia, Blood Loss and the Need for Blood Transfusion in Elective Surgery

Gombotz¹

2012

Transfus Med Hemother

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Patient Blood Management (PBM) describes an evidence-based, multidisciplinary therapeutic approach. Its focus is on the treatment of the individual patient and as such comprises transfusion therapy and pharmacotherapy. Furthermore, the applicability of PBM is not limited to the perioperative setting but is applicable also to other therapeutic measures and disciplines where significant blood loss is known to occur and where transfusion of blood products is part of the established treatment. PBM is fundamentally based on 3 pillars: (1) optimization of the (preoperative) erythrocyte volume, (2) reduction of diagnostic, therapeutic, or intraoperative blood loss, and (3) increasing individual tolerance towards anemia and accurate blood transfusion triggers. PBM primarily identifies patients at risk of transfusion and provides a management plan aimed at reducing or eliminating the risk of anemia and the need for allogeneic transfusion, thus reducing the inherent risks, inventory pressures, and the escalating costs associated with transfusion.

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Section: Increase and Use Of Individual Tolerance To Anemiamentioning

confidence: 99%

Patient Blood Management: A Patient-Orientated Approach to Blood Replacement with the Goal of Reducing Anemia, Blood Loss and the Need for Blood Transfusion in Elective Surgery

Gombotz¹

2012

Transfus Med Hemother

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“…Es existieren derzeit keine belastbaren Daten, die eine regelhafte Transfusion über einen Hb-Zielwert von 9 g/dl hinaus rechtfertigen [10]. Vielmehr bleibt die Transfusion von Fremdbluttrotz ständiger Bemühungen um die Prozessoptimierung bei der Herstellung und Transfusion von allogenen Blutproduktenimmer noch mit einem Restrisiko für den Empfänger behaftet (Übertragung von Infektionen, allergische und immunologische Transfusionsrisiken und insbesondere das während einer Notfalltransfusion signifikant erhöhte Risiko einer Fehltransfusion) [7].…”

Section: Arterieller Sauerstoffgehaltunclassified

Management des massiven intraoperativen Blutverlusts anhand eines Fallbeispiels

Pape¹,

Ippolito²,

Warszawska³

et al. 2017

Anästhesiol Intensivmed Notfallmed Schmerzther

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Massive intraoperative bleeding is a major and potentially life-threatening complication during surgical procedures. The lethal triade of hemorrhagic shock with metabolic acidosis, hypothermia and coagulopathy enhances bleeding tendency. Avoiding this vitious circle requires a well-structured and standardized procedure. Primary goals include the maintenance of adequate tissue oxygenation, restauration of proper coagulatory function, normothermia and homeostasis of acid-base and electrolyte balance. In the present article, these therapeutic goals and their pathophysiological background are illustrated with a clinical case example.

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“…in Grenzsituationen effektiv steigern zu kön-nen (Übersicht und ausführliches Literaturverzeichnis in [30]). …”

Section: Nutzung Der Natürlichen Anämietoleranz Des Patientenunclassified

Perioperative management of Jehovah’s Witness patients

Häbler

Voß

2010

Anaesthesist

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The religious organization of Jehovah's Witnesses numbers more than 7 million members worldwide, including 165,000 members in Germany. Although Jehovah's Witnesses strictly refuse the transfusion of allogeneic red blood cells, platelets and plasma, Jehovah's Witness patients may nevertheless benefit from modern therapeutic concepts including major surgical procedures without facing an excessive risk of death. The present review describes the perioperative management of surgical Jehovah's Witness patients aiming to prevent fatal anemia and coagulopathy. The cornerstones of this concept are 1) education of the patient about blood conservation techniques generally accepted by Jehovah's Witnesses, 2) preoperative optimization of the cardiopulmonary status and correction of preoperative anemia and coagulopathy, 3) perioperative collection of autologous blood, 4) minimization of perioperative blood loss and 5) utilization of the organism's natural anemia tolerance and its acute accentuation in the case of life-threatening anemia.

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Perioperative Anämietoleranz

Cited by 25 publications

References 119 publications

Patient Blood Management: A Patient-Orientated Approach to Blood Replacement with the Goal of Reducing Anemia, Blood Loss and the Need for Blood Transfusion in Elective Surgery

Patient Blood Management: A Patient-Orientated Approach to Blood Replacement with the Goal of Reducing Anemia, Blood Loss and the Need for Blood Transfusion in Elective Surgery

Management des massiven intraoperativen Blutverlusts anhand eines Fallbeispiels

Perioperative management of Jehovah’s Witness patients

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