Perioperative analgesia and the effects of dietary supplements

Abe, Andrew M.; Kaye, Alan D.; Gritsenko, Karina; Urman, Richard D.; Kaye, Adam M.

doi:10.1016/j.bpa.2014.04.002

Cited by 15 publications

(12 citation statements)

References 13 publications

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“…It should be kept in mind that a micronutrient intake in excessive amounts may cause/adversely affect the absorption of another micronutrient element, and its use alongside other drugs may cause pharmacokinetic or pharmacodynamic interactions. 21,28,29 Optimal nutrition is essential for strengthening the immune system in defense against infections. For this reason, we think that individuals at risk for COVID-19 infection (old age, male, chronic disease, smoking, etc.)…”

Section: Discussionmentioning

confidence: 99%

Increased Use of Dietary Supplements and Herbal Products in Adults During COVID-19: A Cross-Sectional Study

Altun¹,

Kürklü²,

Ermumcu³

2022

Turkiye Klinikleri J Health Sci

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Coronaviruses (CoVs) are single-stranded, positive-polarity, enveloped RNA viruses that target the respiratory tract in humans and animals. They can cause mild infections such as the common cold to more serious infections such as Middle East Respi-ratory Syndrome (MERS) and severe acute respiratory syndrome (SARS). 1,2 For the first time in December 2019, after the detection of pneumonia cases of unknown etiology in the Wuhan, Hubei province, China, it was identified that the cause of the disease

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Section: Discussionmentioning

confidence: 99%

Increased Use of Dietary Supplements and Herbal Products in Adults During COVID-19: A Cross-Sectional Study

Altun¹,

Kürklü²,

Ermumcu³

2022

Turkiye Klinikleri J Health Sci

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“…Leak (2000) warns that the use of Hypericum perforatum, Piper methysticum and Valeriana officinalis during the perioperative period may affect anesthesia. It is suggested that the anesthesiologists should ask their presurgical patients about any medications they are taking, including herbal supplements and other alternative substances, and should decide about the discontinuation of the supplements when necessary, since these products can interfere with anesthesia and potentially cause complications during surgery (Kaye et al, 2007;Whinney, 2009;Abe et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol

Pires

Mendes

Pires

et al. 2018

Braz. J. Pharm. Sci.

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Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as monoamine oxidase A inhibitors. This combination produces a pronounced activation of serotonergic pathways and presents potential interaction with other psychotropics. The objective of this study was to investigate the possible interactions between ayahuasca and agents employed in general anesthesia. The pharmacological interactions between ayahuasca and morphine or propofol were evaluated in mice using doses of 12, 120 and 1200 mg/kg (0.1 to 10 times the average dose consumed by humans in religious rituals). Ayahuasca alone showed an antinociceptive effect in the writhing and formalin tests, and intensified the analgesic effect of morphine in the hot plate test. Concerning the pharmacological interactions between ayahuasca and propofol, the results were opposite; ayahuasca intensified the depressant effect of propofol in the rotarod test, but decreased the sleeping time induced by propofol. These set of results showed the occurrence of some interactions between ayahuasca and the drugs morphine and propofol, possibly by both pharmacokinetics and pharmacodynamics mechanisms.

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“…May act additively or synergistically with anesthetics, benzodiazepines, and opiates in the perioperative setting causing excessive sedation. 8,86,87 Kola nut Consider holding 2 weeks. At a minimum, patients should be encouraged to taper intake.…”

Section: Kavamentioning

confidence: 99%