Periodical crystallization variability

Influence of the Estimation Procedure on the Accuracy and Precision of Aluminum Trihydroxide Crystallization Kinetics from Dynamic Data

“…Melikhov et al . proposed models to describe the variability distribution of certain crystal properties due to fluctuations in certain process conditions.…”

“…Poor reproducibility of crystallization kinetics estimates may be attributed to the following: (1) small random and systematic variations in the local conditions 10 that affect the measurements from which the kinetics are estimated; (2) differences in (or poor) experimental design that affect the form and information content of the experimental data; (3) large uncertainties associated with the parameter estimation procedures. The first issue can be considered a property of the laboratory, its crystallizers, operating procedures, sampling methods, and analysis methods.…”

“…Ideally, a laboratory would have conducted sufficient repeats to quantify this uncertainty. Melikhov et al 10 proposed models to describe the variability distribution of certain crystal properties due to fluctuations in certain process conditions.…”

Condensation route of evolution of nanodispersed substances

“…The ξ(l,t) function was found to be centered and delta correlated. The magnitude of the growth fluctuations of the nanocrystals can be estimated from published data, 27 which states that the rate of propagation of the monolayer over the surface of the growing BaSO 4 nanocrystal can randomly change several fold. Substantial fluctuations of the growth rate are also indicated by high magnitudes of parameter a given in Table 1.…”