Periocular Squamous Cell Carcinoma

Sun, Michelle T.; Andrew, Nicholas H; O’Donnell, Brett A; McNab, Alan A.; Huilgol, Shyamala C.; Selva, Dinesh

doi:10.1016/j.ophtha.2015.04.002

Cited by 37 publications

(34 citation statements)

References 17 publications

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“…The high TNM and the American Joint Committee on Cancer staging are associated with local recurrence and metastasis. [ 12 13 ]…”

Section: Epithelial Eyelid Tumorsmentioning

confidence: 99%

Pathology of eyelid tumors

Pe’er

2016

Indian J Ophthalmol

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The eyelids are composed of four layers: skin and subcutaneous tissue including its adnexa, striated muscle, tarsus with the meibomian glands, and the palpebral conjunctiva. Benign and malignant tumors can arise from each of the eyelid layers. Most eyelid tumors are of cutaneous origin, mostly epidermal, which can be divided into epithelial and melanocytic tumors. Benign epithelial lesions, cystic lesions, and benign melanocytic lesions are very common. The most common malignant eyelid tumors are basal cell carcinoma in Caucasians and sebaceous gland carcinoma in Asians. Adnexal and stromal tumors are less frequent. The present review describes the more important eyelid tumors according to the following groups: Benign and malignant epithelial tumors, benign and malignant melanocytic tumors, benign and malignant adnexal tumors, stromal eyelid tumors, lymphoproliferative and metastatic tumors, other rare eyelid tumors, and inflammatory and infections lesions that simulate neoplasms.

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“…The high TNM and the American Joint Committee on Cancer staging are associated with local recurrence and metastasis. [ 12 13 ]…”

Section: Epithelial Eyelid Tumorsmentioning

confidence: 99%

Pathology of eyelid tumors

Pe’er

2016

Indian J Ophthalmol

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“…Accurate staging of an eyelid tumor is based on the Tumor, Node and Metastasis (TNM) classification, and it is important, among others, to help the clinician in the planning of treatment [8,9]. The T-staging of eyelid tumors encompasses determination on whether there is an invasion of the eyelid structures such as the tarsal plate and orbital septum [8,9], which are not clinically accessible and, therefore, imaging can be crucial [10] for an accurate evaluation.…”

Section: Introductionmentioning

confidence: 99%

MR and CT Imaging of the Normal Eyelid and its Application in Eyelid Tumors

Ferreira

Pinheiro

Saraiva

et al. 2020

Cancers

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T-staging of most eyelid malignancies includes the assessment of the integrity of the tarsal plate and orbital septum, which are not clinically accessible. Given the contribution of MRI in the characterization of orbital tumors and establishing their relations to nearby structures, we assessed its value in identifying different eyelid structures in 38 normal eyelids and evaluating tumor extension in three cases of eyelid tumors. As not all patients can receive an MRI, we evaluated those same structures on CT and compared both results. All eyelid structures were identified on MRI and CT, except for the conjunctiva on both techniques and for the tarsal muscles on CT. Histopathology confirmed the MRI findings of orbital septum invasion in one patient, and the MRI findings of intact tarsus and orbital septum in another patient. Histopathology could not confirm or exclude tarsal invasion seen on MRI on two patients. Although imaging the eyelid is challenging, the identification of most eyelid structures is possible with MRI and, to a lesser extent, with CT and can, therefore, have an important contribution to the T-staging of eyelid tumors, which may improve treatment planning and outcome.

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“…With the exception of retinoblastoma and melanoma of the uveal tract, primitive ocular cancers originate from the accessory structures of the eye, especially the eyelids and the conjunctiva [1][2][3]. While in developed countries these cancers are mostly encountered after the age of 60, in black Africa their prevalence has increased in Young adults [1,4].…”

Section: Introductionmentioning

confidence: 99%

Primitive Ocular Cancers in the University Hospital of Brazzaville

2019

JOCR

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Introduction:With the exception of retinoblastoma and melanoma of the uveal tract, primitive ocular cancers originate from the accessory structures of the eye, especially the eyelids and the conjunctiva. While in developed countries these cancers are mostly encountered after 60 years, in black Africa their prevalence has increased in young adults.Objective: To determine the epidemiological, clinical and histological profile of these tumors in the University Hospital of Brazzaville.Methodology: Mini analysis of nine (9) of our publications, published between 2015 and 2017, in the journals: East African Medical Journal, Health Science and Diseases, EC Ophthalmology, and Revue de Médecine et de Pharmacie. HIV serology has been systematically requested except for cases of retinoblastoma. Histological evidence was made in all cases.Results: 86 patients had been seen. Average age 31.2 years (2 years -75 years), sex ratio equal to 1.08. Reasons for consultation: exophthalmia (44), mass (35%), leucocoria (20%) and palpebral wounds (1%). Affected structures: conjunctiva (38%), retina (35%) and eyelid (27%). Histological types: squamous cell carcinoma (55.5%), retinoblastoma (25.9%), basal cell carcinoma (8.5%), sebaceous carcinoma (5.5%), Kaposia's sarcoma (3.5%) and acral melanoma lentiginous (1.1%). HIV serology was positive in 38% overall, but in 100% of conjunctival cancers.

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Periocular Squamous Cell Carcinoma

Cited by 37 publications

References 17 publications

Pathology of eyelid tumors

Pathology of eyelid tumors

MR and CT Imaging of the Normal Eyelid and its Application in Eyelid Tumors

Primitive Ocular Cancers in the University Hospital of Brazzaville

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