Perineural Invasion by Keratoacanthoma

Lapins, Nikolajs A.

doi:10.1001/archderm.1980.01640310061021

Cited by 58 publications

(26 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This compares with 8 cases with perineural invasion in 2000 KAs (0.4%) from the Armed Forces Institute of Pathology. 15 and 4 cases in 250 KAs (1.6%) reported by Cooper and Wolfe 16 in 1988, and collected over an 8-year period. The distribution of cases in this series, largely on the head and neck, is higher than that in the series by Goldbolt et al, 4 but it must be admitted that the author (D.D.W.)…”

mentioning

confidence: 88%

Squamous Cell Carcinoma Arising in Keratoacanthoma: A Neglected Phenomenon in the Elderly

Weedon

Malo

Brooks

et al. 2010

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Keratoacanthoma is a unique clinicopathologic entity with a behavior and clinical outcome that differs markedly from that of squamous cell carcinoma. The development of squamous cell carcinoma in a keratoacanthoma alluded to by Rook and Whimster in 1979 and by Reed in 1993 was confirmed by Sánchez Yus et al in 2000. We found this phenomenon in 5.7% of keratoacanthomas in a series of 3465 cases. Its incidence in patients older than 90 years was 13.9%. The incidence of perineural invasion in this series of keratoacanthomas was 0.2%.

show abstract

mentioning

confidence: 88%

Squamous Cell Carcinoma Arising in Keratoacanthoma: A Neglected Phenomenon in the Elderly

Weedon

Malo

Brooks

et al. 2010

The American Journal of Dermatopathology

View full text Add to dashboard Cite

show abstract

“…Although perineural invasion has been described in the early proliferative stage, the invasions do not adversely influence the biologic behavior and the prognosis. 7 Mohs micrographic surgery has been recommended for large lesions of KCM. 1 In several cases, multiple KAs have been successfully treated with oral retinoid.…”

Section: Keratoacanthoma Centrifugum Marginatum: a Rare Variant Of Kementioning

confidence: 99%

Keratoacanthoma Centrifugum Marginatum: A Rare Variant of Keratoacanthoma

et al. 2010

View full text Add to dashboard Cite

“…Auch bei KA wurde neurotropes Wachstum beobachtet (⊡ Tabelle 2), in seltenen Fällen mit Befall von Hirnnerven und intrakraniellen Strukturen [25] sowie Lymphknotenmetastasen [6,25,26,39,58].Die Ansicht,dass es sich bei KA um eine Variante des PEK handelt,scheint durch einen Fall betätigt, bei dem ein primär klassisches KA nach Ausbreitung in den Sinus cavernosus in der Histologie das Bild eines PEK aufwies [25]. Dennoch wird die Dignität neurotroper KA unterschiedlich beurteilt.In einigen Arbeiten wird das KA trotz neurotropem Wachstums als benigne eingestuft [13,22,28,33,47]. Wichtig erscheint bei neurotropem Wachstum eine komplette Exzision oder intraläsionale MethotrexatInjektion [63], um ein weiteres Tiefenwachstum zu unterbinden.…”

Section: Fallunclassified