Perinatal outcome and long-term pediatric morbidity of pregnancies with a fibroid uterus

Harlev, Avi; Wainstock, Tamar; Walfisch, Asnat; Landau, Daniella

doi:10.1016/j.earlhumdev.2019.01.004

Cited by 9 publications

(8 citation statements)

References 29 publications

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“…Leiomyoma is the most common pelvic benign tumor in women of reproductive age. Many studies have focused on the detrimental influence of leiomyoma on pregnancy outcomes 2,5,7 . It is commonly believed that subserous leiomyoma has negligible adverse influence on pregnancy, 7 whereas intramural leiomyoma has controversial adverse influence on pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies have focused on the detrimental influence of leiomyoma on pregnancy outcomes. 2,5,7 It is commonly believed that subserous leiomyoma has negligible adverse influence on pregnancy, 7 whereas intramural leiomyoma has controversial adverse influence on pregnancy. However, in the case of women with pregnancies complicated by leiomyoma, they worry about not only the pregnancy outcomes, but also the changes of the leiomyoma during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…Women with pregnancies complicated by leiomyoma may need to undergo prenatal myomectomy and may experience iatrogenic preterm birth 6 . Meanwhile, no adverse impact on future health of the offspring can be concluded 7 . However, the size change of uterine leiomyoma during pregnancy is deemed controversial.…”

Section: Introductionmentioning

confidence: 99%

“…6 Meanwhile, no adverse impact on future health of the offspring can be concluded. 7 However, the size change of uterine leiomyoma during pregnancy is deemed controversial. It is widely believed that leiomyoma size increases rapidly owing to the influence of estrogen and progestin.…”

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confidence: 99%

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Change of uterine leiomyoma size during pregnancy and the influencing factors: A cohort study

Tian

Wang

et al. 2021

Intl J Gynecology & Obste

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Uterine leiomyoma is the most common pelvic benign tumor in women of reproductive age, and its prevalence is known to increase with age. 1 The prevalence of leiomyoma in pregnancy is 2.8%-16.7%. [2][3][4] As a result of the limitation that physical examination and ultrasound examination focuses on the fetus instead of the leiomyoma for pregnant women, the prevalence may be underestimated. With advanced age at pregnancy, the increasing obesity rate, and the implemented three-child policy in China, the prevalence of leiomyoma during pregnancy is increasing.It is commonly believed that uterine leiomyoma appears to negatively impact perinatal outcomes. 5 Women with pregnancies complicated by leiomyoma may need to undergo prenatal myomectomy

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Change of uterine leiomyoma size during pregnancy and the influencing factors: A cohort study

Tian

Wang

et al. 2021

Intl J Gynecology & Obste

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“…Numerous mechanisms of UFs influence fertility. They include implantation disorders, impairment of blood flow in the uterine tissue, endocrine disorders and deceleration or inability to transport gametes [33]. UFs may significantly complicate pregnancy and their incidence during pregnancy increases because of the fact that the number of older mothers is on the rise [34].…”

Section: Uterine Fibroids During Preconception and Pregnancymentioning

confidence: 99%

The role of magnetic resonance-guided focused ultrasound in fertility sparing treatment of uterine fibroids—current perspectives

Ciebiera¹,

Łoziński²

2020

ecancer

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Uterine fibroids (UFs) are the most common benign tumours of the female reproductive system and the most frequent reason for hysterectomy worldwide. UFs are reported in 20%-70% of women of reproductive age depending on a study group. Although most women with UFs are asymptomatic, over 30% of them will present with different symptoms. Abnormal uterine bleeding, pain, pressure and infertility are the most common. Lesions that cause these kinds of symptoms may require medical intervention.Trends in UF treatment change along with patient awareness and the introduction of new methods and techniques. Selecting an appropriate treatment option should be individualised and adjusted to the patient's expectations as much as possible. This choice will mostly depend on the patient's age, UF location, the size and number of lesions, severity of symptoms and, most importantly, the patient's expectations concerning the preservation of fertility. Observations made for the past few years showed an increasing number of pre-and perimenopausal women who wish to preserve their uterus or decline surgery. In line with current trends and demands in medicine, great importance is attached to the development and upgrade of new minimally invasive or noninvasive procedures in UF therapy.Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is not associated with severe destruction of the uterine cavity and walls. For this reason, this method may be considered as a kind of hope in fertility-sparing UF therapy and the data about its use in this indication raises future hope. In this review, we summarise the available data on the use of MR-HIFU as a fertility-sparing method in the treatment of UFs. We also indicate how it could evolve in the future.According to the available data, MR-HIFU is a relatively safe noninvasive method which seems not to deteriorate fertility compared to the pre-treatment status. MR-HIFU may constitute an alternative solution and be chosen in patients who meet the qualification criteria and deny other methods, which also facilitates the use of other treatment options in case the procedure is ineffective. Further randomised studies are necessary to confirm the above information.

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The characteristics of a fibroid in pregnancy can influence the perinatal outcome

Višnić

2024

Arch Gynecol Obstet

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Perinatal outcome and long-term pediatric morbidity of pregnancies with a fibroid uterus

Cited by 9 publications

References 29 publications

Change of uterine leiomyoma size during pregnancy and the influencing factors: A cohort study

Change of uterine leiomyoma size during pregnancy and the influencing factors: A cohort study

The role of magnetic resonance-guided focused ultrasound in fertility sparing treatment of uterine fibroids—current perspectives

The characteristics of a fibroid in pregnancy can influence the perinatal outcome

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