Change of uterine leiomyoma size during pregnancy and the influencing factors: A cohort study

Abstract

Uterine leiomyoma is the most common pelvic benign tumor in women of reproductive age, and its prevalence is known to increase with age. 1 The prevalence of leiomyoma in pregnancy is 2.8%-16.7%. [2][3][4] As a result of the limitation that physical examination and ultrasound examination focuses on the fetus instead of the leiomyoma for pregnant women, the prevalence may be underestimated. With advanced age at pregnancy, the increasing obesity rate, and the implemented three-child policy in China, the prevalence of leiomyoma during pregnancy is increasing.It is commonly believed that uterine leiomyoma appears to negatively impact perinatal outcomes. 5 Women with pregnancies complicated by leiomyoma may need to undergo prenatal myomectomy

Laparoscopic myomectomy – The importance of surgical techniques

“…Pre-operative medical treatments can be used to minimize the specific complications and to optimize the results ( 68 ). Even though there are important risks related with this procedures, the presence of uterine leiomyomas during pregnancy influences the evolution and outcomes ( 69 , 70 ). With or without surgery, uterine fibroids represent an risk for infertility that needs to be proper addressed ( 71 ).…”

Sciatica in Early Pregnancy With Coexisting Uterine Leiomyoma and‌ ‌Tarlov‌ ‌Cyst:‌ ‌A‌ ‌Case Report

“…During menopause, uterine fibroids tend to regress, alleviating symptoms, but sometimes fibroids occur within this age group, especially among African Americans [6]. In a cohort study by Templeman et al, the second incidence of uterine fibroid was among women aged 50-54 years [7]. However, in the case of this 25-year-old, her symptoms subsided in the first trimester as the pregnancy grew in size.…”

Symptoms, diagnosis and treatment of submucous fibroids

“…( During pregnancy, fibroids can grow rapidly, mainly in the first half of pregnancy, more so for women with a higher BMI but not for multiparous women and women with higher maternal age. Delli et al 2019;Rosati et al 1992;Tian et al 2022)…”

“…Smaller fibroids are more likely to grow during pregnancy than larger fibroids (Tian et al 2022). Although over half of fibroids decreased about 35% in size during pregnancy (Hammoud et al 2006).…”