Perinatal Outcome Among Singleton Infants Conceived Through Assisted Reproductive Technology in the United States

Birth outcomes of intended pregnancies among women who used assisted reproductive technology, ovulation stimulation, or no treatment

“…This is higher than other reports because our study was restricted to women who were trying to become pregnant, rather than the entire birth population (2). We confirmed the previously reported relationship that singleton infants born to mothers who undergo ART procedures are more likely to be low birthweight (11)(12)(13)(14)(15), preterm (13,14,30), or SGA (13,30,31) than singleton infants born to mothers who did not undergo treatment. We further provide one of a few studies of this size and diversity showing an association between the use of ovulation stimulation medications without ART and infants being born small for gestational age for singleton infants.…”

“…In addition to problems associated with multiple gestation deliveries, studies have found that singleton ART-conceived infants are more likely to be low birthweight compared with singletons whose mothers did not use ART (11)(12)(13)(14). Some studies have also found a greater risk of birth defects among singletons and multiples conceived using ART compared with those conceived without treatment (15)(16)(17)(18); however, the evidence is inconsistent and suggests that risk may be related to underlying infertility (19)(20)(21).…”

Live birth rates and birth outcomes by diagnosis using linked cycles from the SART CORS database

“…Less is known about whether diagnosis has a direct effect on length of gestation and birthweight. One study [6] reported an increase in low birthweight at term for patients with a diagnosis of male factor infertility.…”

Crianças nascidas após emprego de técnica de fertilização assistida

“…20 Quanto à população geral, a literatura relata um aumento da incidência de prematuridade, não somente entre os múltiplos, como também entre os RN de parto único concebidos de técnicas de RHA. 21 Apesar do critério "termo" não pressupor a maturidade plena do concepto, a maioria das crianças neste trabalho foi classificada como RN de termo (37semanas ou mais de idade gestacional), sem diferenças significativas entre os dois procedimentos analisados. Todavia, comparando-se com dados brasileiros, deve-se salientar que a taxa de prematuridade no Brasil, segundo o IBGE 22 , em 2006, foi aproximadamente cinco vezes menor do que a taxa aqui encontrada.…”