Perinatal outcome after multifetal reduction: A study of 12 cases

Palshetkar, Nandita; Pai, Hrishikesh; Pisat, Suchita; Gogate, Jaya; Bansal, Bharathi; Pisat, Sanket

doi:10.1007/s13224-011-0043-6

Cited by 2 publications

(4 citation statements)

References 11 publications

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“…Our percentage of abortion is higher than some previous studies as well. [ 4 ] As ours is a retrospective analysis and the follow-up of patients beyond 12 weeks was not done at our own center in all cases, the reasons for such high abortion rates are not clear. It is possible that some of our patients were not under expert medical care after the second trimester and therefore were not as closely monitored as was required.…”

Section: Discussionmentioning

confidence: 99%

“…In an Indian prospective study,[ 4 ] 45% patients (5/12) carried the pregnancy to term. This is very similar to our own study, wherein 44.2 (29/65) patients delivered at term even though the average gestational age of the entire cohort was 32.14 weeks.…”

Section: Discussionmentioning

confidence: 99%

“…[ 2 3 ] The length of gestation is inversely proportional to the number of intrauterine fetuses. [ 4 ] Maternal complications for women carrying high-order multiple gestations include increased incidence of preeclampsia, cesarean delivery, postpartum hemorrhage, and fatty liver. [ 3 5 ]…”

Section: Introductionmentioning

confidence: 99%

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Comparative analysis of perinatal outcome of spontaneous pregnancy reduction and multifetal pregnancy reduction in triplet pregnancies conceived after assisted reproductive technique

et al. 2016

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INTRODUCTION:With the advent of assisted reproductive treatment options, the incidence of multiple pregnancies has increased. Although the need for elective single embryo transfer is emphasized time and again, its uniform applicability in practice is yet a distant goal. In view of the fact that triplet and higher order pregnancies are associated with significant fetomaternal complications, the fetal reduction is a commonly used option in such cases. This retrospective study aims to compare the perinatal outcome in patients with triplet gestation who have undergone spontaneous fetal reduction (SFR) as against those in whom multifetal pregnancy reduction (MFPR) was done.MATERIALS AND METHODS:In the present study, eighty patients with triplet gestation at 6 weeks were considered. The patients underwent SFR or MFPR at or before 12–13 weeks and were divided into two groups (34 and 46), respectively.RESULTS:Our study found no statistical difference in perinatal outcome between the SFR and MFPR groups in terms of average gestational age at delivery, abortion rate, preterm delivery rate, and birth weight. The study shows that the risk of aborting all fetuses after SFR is three times (odds ratio [OR] = 3.600, 95% confidence interval [CI] = 0.2794–46.388) that of MFPR in subsequent 2 weeks. There were more chances of loss of extra fetus in SFR (23.5%) group than MFPR group (8.7%) (OR = 3.889, 95% CI = 1.030–14.680). As neither group offers any significant benefit from preterm delivery, multiple pregnancies continue to be responsible for preterm delivery despite fetal reduction.CONCLUSION:There appears to be some advantages of MFPR in perinatal outcome when compared to SFR, especially if the latter happens at advanced gestation. Therefore, although it is advisable to wait for SFR to occur, in patients with triplet gestation at 11–12 weeks, MFPR is a viable option to be considered.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Comparative analysis of perinatal outcome of spontaneous pregnancy reduction and multifetal pregnancy reduction in triplet pregnancies conceived after assisted reproductive technique

et al. 2016

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“…12,13 However, to our knowledge, there is not enough data about the effects of fetal reduction in triplet pregnancies In Indian women except a study of 12 cases of triplet pregnancy. 14 The aim of this study is to review the effects of fetal reduction in triplet pregnancies with focus on risk of miscarriage and preterm delivery in Indian women and thus provide the local data for counseling the prospective parents.…”

Section: Introductionmentioning

confidence: 99%

Selective Fetal Reduction in Triplet Pregnancy: Indian Experience — A Retrospective Review of 32 Cases

Chaudhury¹,

Mukherjee²

2014

Journal of South Asian Federation of Obstetrics and Gynaecology

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Aim:To review the effects of selective fetal reduction in trichorionic triplet pregnancy with focus on risk of miscarriage and preterm delivery in Indian women and thus provide local data for counseling the prospective parents in similar situation. Materials and methods:This retrospective study reviewed the pregnancy outcome of 32 sets of triplet pregnancies following fetal reduction. All mothers had trichorionic triplet pregnancy with three live fetuses at 10 to 11 weeks of gestation. One to two milliliter ml of 10% potassium chloride (KCl) was injected into the heart of the target fetus to achieve asystole. Results:The miscarriage (pregnancy loss before 24 completed weeks) rate in our study was 3.12%. The delivery in our study at ≤32 and ≤35 weeks were 6.45 and 51.61% respectively. The mean gestational age (mean ± SD) of the mothers was 242.58 ± 12.93 days. Regarding the birthweight of neonates, 5.08% babies were <1500 gm, 89.83% were between 1500 and ≤2500 gm and 5.08% were > 2500 gm. The mean birth weight (mean ± SD) of the babies was 1921.18 ± 339.78 gm. There was no neonatal death in this cohort. Conclusion:Our study results, when compared with 'expectant management' group of two European studies as there was no control in our study, appeared significantly better in terms of gestational age at delivery and neonatal birth weight.Selective fetal reduction remains an effective option to Indian women with trichorionic triplet pregnancy.

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Perinatal outcome after multifetal reduction: A study of 12 cases

Cited by 2 publications

References 11 publications

Comparative analysis of perinatal outcome of spontaneous pregnancy reduction and multifetal pregnancy reduction in triplet pregnancies conceived after assisted reproductive technique

Comparative analysis of perinatal outcome of spontaneous pregnancy reduction and multifetal pregnancy reduction in triplet pregnancies conceived after assisted reproductive technique

Selective Fetal Reduction in Triplet Pregnancy: Indian Experience — A Retrospective Review of 32 Cases

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