Perinatal Factors and the Risk of Developing Anorexia Nervosa and Bulimia Nervosa

Favaro, Angela; Tenconi, Elena; Santonastaso, Paolo

doi:10.1001/archpsyc.63.1.82

Cited by 144 publications

(201 citation statements)

References 32 publications

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“…Several studies (on families, twins, DNA) [17][18][19][20][21][22][23] seem to suggest that about 50% of the risk is due to genetic factors. Environmental risk factors can be multiple and are divided into early and late; Early Risk Factors are all those conditions that interfere with the early stages of neuro-development and maturation of stress response systems and include intrauterine life conditions, perinatal complications and early alterations in relationship with figures of care [24]. Late environmental risk factors can be considered conditions of loss or trauma, abuse and neglect in childhood, psychosocial stress and strongly conflicting relationships between parents and parents and children, psychoactive substance abuse and the exposure to pressures towards the thinness by members of the family group or the relational, affective, ethnic and cultural area in which the subject lives [4].…”

Section: The Ed Etiopathogenesismentioning

confidence: 99%

The role of endocannabinoids in the control of eating disorders

Milano¹,

Tecce²,

Capasso³

2017

Dis Disord

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Eating Disorder (ED) is a syndrome characterized by persistent alteration of eating behavior and the conditions that cause an insufficient ingestion and/or adsorption of foods. There are three different ED diseases: Anorexia Nervosa (AN), Bulimia Nervosa (BN) and Binge Eating Disorders (BED). ED are complex conditions that arise from a combination of long-standing behavioral, emotional, psychological, interpersonal, and social factors. The neuronal circuits that control the ingestion of food are mainly related to catecholaminergic, serotoninergic and peptidergic systems. In this respect, while serotonin, dopamine and prostaglandin promote the ingestion of food, by contrast, neuropeptide Y, norepinephrine, GABA and opioid peptides inhibit food ingestion thus causing the occurrence of ED. The drugs mainly used in the treatment of ED are antidepressants such as selective serotonin reuptake inhibitors and tricyclic antidepressant. Additionally, mood stabilizers (lithium), anxiolytics, serotonin and noradrenalin reuptake inhibitors and antipsychotic drugs are often used in the treatment of ED.Several studies indicate that the endocannabinoid system is involved in ED supporting the idea that the cannabinoid signaling system is a key modulatory element in the activity in the brain area associated with ED.

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Section: The Ed Etiopathogenesismentioning

confidence: 99%

The role of endocannabinoids in the control of eating disorders

Milano¹,

Tecce²,

Capasso³

2017

Dis Disord

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“…Healthy women within the same age range were recruited from the general population and among volunteers, as described in previous studies. 5,20,21 A description of the samples is given in Appendix 1, available at cma.ca/jpn. All patients with anorexia nervosa had to meet DSM-IV criteria for anorexia nervosa in their lifetime; however, patients could be at different stages of their illness at the time of neuropsychological assessment.…”

Section: Participantsmentioning

confidence: 99%

Catechol-O-methyltransferase genotype modifies executive functioning and prefrontal functional connectivity in women with anorexia nervosa

Favaro¹,

Clementi²,

Manara³

et al. 2013

J Psychiatry Neurosci

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“…Anoreksija nervoza povezuje se s porodičnom istorijom opsesivno-kompulzivnog poremećaja, poremećaja raspoloženja, posebno depresije, alkoholizma i zloupotrebe supstance (Treasure, 2007). Na razvoj poremećaja mogu uticati i komplikacije tokom trudnoće, neadekvatna ishrana pre i posle porođaja, nutritivni status i planiranje ishrane tokom života, mala težina na rođenju, prevremeno rođenje ili trauma prilikom rođenja (Favaro et al,, 2006).…”

Section: Biološki Faktoriunclassified

Risk factors in the development of anorexia nervosa

Lazarevic¹,

Batinić²,

Vukosavljević‐Gvozden³

2013

Psihol istra

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Anoreksija nervoza predstavlja složen poremećaj ishrane čije su osnovne karakteristike voljno smanjivanje i održavanje telesne težine na nivou ispod 85% od optimalne, iracionalan strah od hrane i gojaznosti, kao i poremećaj doživljaja telesne težine i oblika tela. Na razvoj, održavanje i kompleksnost simptoma utiču različiti biološki, psihološki i socijalni faktori. Cilj rada jeste predstavljanje faktora rizika koji mogu značajno doprineti razvoju i izraženosti simptoma anoreksije nervoze. Reč je o preglednom radu u kojem su prikazani ključni faktori koji utiču na nastanak i održavanje poremećaja. Posebno detaljno diskutovani su stilovi afektivnog vezivanja, perfekcionizam i zabrinutost povodom oblika tela, što predstavlja sržne psihološke faktore koji utiču na razvoj i izraženost simptoma dominantno prisutnih u kliničkoj slici. Nedostatak samopoštovanja i samopouzdanja, nerazrešeni emocionalni problemi, visoki, nerealistični standardi i ideali fizičkog izgleda kojih se osoba rigidno drži i uporno i dosledno pokušava da dostigne, nezadovoljstvo oblikom tela, odnosno izražena diskrepanca između doživljaja opaženog i zamišljene slike idealnog tela -povezani su sa maladaptivnim stavovima i navikama u vezi sa ishranom i često prethode dijagnozi anoreksije nervoze. Istraživanja ukazuju na to da su nesigurni stilovi emocionalnog vezivanja, perfekcionizam i zabrinutost povodom oblika tela značajno povezani sa simptomima anoreksije nervoze i da predstavljaju značajne predisponirajuće i održavajuće faktore. Fokusiranje na navedne probleme može značajno doprineti sveobuhvatnijoj prevenciji i tretmanu poremećaja.Ključne reči: anoreksija nervoza, afektivno vezivanje, perfekcionizam, zabrinutost povodom oblika tela UvodAnoreksija nervoza jeste psihološki poremećaj čiju suštinu predstavljaju promene u ponašanju u vezi sa ishranom, kako bi se smanjio apetit i postigao gubitak telesne 1 Članak predstavlja rezultat rada na projektu "Identifikacija, merenje i razvoj kognitivnih I emocionalnih kompetencija važnih društvu orijetnisanom na evropske integracije" (br. 179018) koji finansira Ministarstvo prosvete, nauke i tehnološkog razvoja Republike Srbije.2 Student doktorskih studija,

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Perinatal Factors and the Risk of Developing Anorexia Nervosa and Bulimia Nervosa

Abstract: A significantly higher risk of eating disorders was found for subjects with specific types of obstetric complications. An impairment in neurodevelopment could be implicated in the pathogenesis of eating disorders.

Cited by 144 publications

References 32 publications

The role of endocannabinoids in the control of eating disorders

The role of endocannabinoids in the control of eating disorders

Catechol-O-methyltransferase genotype modifies executive functioning and prefrontal functional connectivity in women with anorexia nervosa

Risk factors in the development of anorexia nervosa

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