Perifoveal Exudative Vascular Anomalous Complex-Like Lesion as a Complication of Prepapillary Arterial Loops

Ayachit, Apoorva; Sacconi, Riccardo; Joshi, Shrinivas; Querques, Giuseppe

doi:10.3928/23258160-20181203-11

Cited by 18 publications

(8 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Treatment of PEVAC lesions with laser using CWMYL-577 had been reported previously by Ayachit et al 10 However, in this report the patient had a worse functional and structural outcome with persistency of intraretinal cysts, which could be explained by the different LASER parameters used. Mrejen et al, 11 also reported a patient treated with two sessions of thermal laser (spaced 7 months), with parameters similar to ours (40 ms, 100 mW and 100 µm spot size), and with good results, as well.…”

Section: Np120mentioning

confidence: 51%

Continuous wave milipulse yellow laser treatment for perifoveal exudative vascular anomalous complex-like lesion: A case report

Henriques¹,

Pinto

Rosa³

et al. 2020

European Journal of Ophthalmology

View full text Add to dashboard Cite

Introduction: Perifoveal exudative vascular anomalous complex (PEVAC) is an underdiagnosed macular entity. A striking feature of this entity is the unresponsiveness to anti-VEGF treatment. Continuous wave milipulse yellow laser 577 nm (CWMYL-577) has a high absorption peak for oxyhaemoglobin, which allows for low power density use. Purpose: To report a case of a PEVAC-like lesion unresponsive to anti-VEGF and corticosteroids, successfully treated with a single session of minimally invasive focal laser, using CWMYL-577. Methods: A diabetic patient with a symptomatic PEVAC-like lesion in the right eye, presented with decreased vision (20/100) and cystoid edema that had persisted for the last 18 months, despite multiple intraocular injections of anti-VEGF and long acting corticosteroids. Three spots of low power density CWMYL-577 (100 mW, 25 ms and 100 µm, using lens with no amplification factor) over the lesion were successfully performed in one laser session. One month and three months after the laser procedure, a gradual decrease of edema and lipid exudates was observed and at a 6-month follow-up, the retina had recovered its normal anatomy with visual acuity of 20/20 that have persisted for 4 years after treatment. Conclusions: Minimal invasive focal laser using the CWMYL-577 can be considered an effective therapeutic strategy for symptomatic nonresponding PEVAC-like lesion in patients with DM without DR.

show abstract

Section: Np120mentioning

confidence: 51%

Continuous wave milipulse yellow laser treatment for perifoveal exudative vascular anomalous complex-like lesion: A case report

Henriques¹,

Pinto

Rosa³

et al. 2020

European Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

“…The pathogenesis of PEVAC is not clear, with some speculating ( 2 ) that it is a vascular anomaly of the macular retina and others suggesting that it is a reaction to the slow retinal blood flow between the ramus communicans and interarterial loops ( 8 ). Overall, greater attention should be paid to this disease to avoid misdiagnosis and to clarify its pathogenesis and treatment.…”

Section: Discussionmentioning

confidence: 99%

First report of perifoveal exudative vascular anomalous complex in a healthy Chinese individual: a case description

Liang,

Wu,

et al. 2024

Quant Imaging Med Surg

View full text Add to dashboard Cite

“…The pathogenesis of PVAC and its treatment are not yet established. [1][2][3]6,8 It was first identified in a healthy patient without any other vascular or inflammatory disease. However, in 2019, Venkatsh et al and Zhang et al identified PVAC in a diabetic patient who was unresponsive to anti-VEGF injections.…”

Section: Discussionmentioning

confidence: 99%

Perifoveal exudative vascular anomalous complex and resembling lesions treated with intravitreal triamcinolone

Damasceno

Horowitz²,

Yannuzzi

et al. 2023

European Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose To report the use of intravitreal triamcinolone to treat macular edema associated with isolated perifoveal exudative vascular anomalous complex (PVAC) and resembling lesion (PVAC-RL). Methods In this case series, three diabetic patients (3 eyes) with PVAC-RLs and one healthy patient (1 eye) with PVAC lesion associated with cystic spaces underwent three intravitreal injections of aflibercept before switching to one intravitreal triamcinolone injection in each patient. Results Macular edema improved from 297.5 ± 8.10 μm, at baseline, to 269.2 ± 8.89 μm, after triamcinolone; whereas visual acuity improved from 20/38 to 20/26 (ETDRS). Conclusion PVAC and PVAC-RL are rare and often misdiagnosed lesions that may be associated with decreased vision. Our outcomes suggest that intravitreal injection of triamcinolone may be an effective and affordable treatment for PVAC and PVAC-RL with intraretinal fluid.

show abstract

Perifoveal Exudative Vascular Anomalous Complex-Like Lesion as a Complication of Prepapillary Arterial Loops

Cited by 18 publications

References 7 publications

Continuous wave milipulse yellow laser treatment for perifoveal exudative vascular anomalous complex-like lesion: A case report

Continuous wave milipulse yellow laser treatment for perifoveal exudative vascular anomalous complex-like lesion: A case report

First report of perifoveal exudative vascular anomalous complex in a healthy Chinese individual: a case description

Perifoveal exudative vascular anomalous complex and resembling lesions treated with intravitreal triamcinolone

Contact Info

Product

Resources

About