Perianal mantle cell lymphoma mimicking an external thrombosed hemorrhoid: a case report

Abstract

IntroductionMalignancies of the anal margin and perianal skin are relatively uncommon, and account for approximately 2% to 3% of all anorectal malignancies. Despite the fact that gastrointestinal presentation of lymphoma is not uncommon, primary localization of mantle cell lymphoma to the perianal region is rare.Case presentationWe present the case of a 64-year-old Turkish man with a rapidly progressive perianal mass. Our patient had previously required medical treatment on multiple occasions for hemorrhoidal disease; however, the treatment was ineffective and gross lymph nodes were noted in his left inguinal region. Following excision of the mass and his lymph nodes, the pathological diagnosis of both tissues was mantle cell lymphoma.ConclusionAlthough gastrointestinal presentation of non-Hodgkin lymphoma is common, the literature includes only a few cases of perianal localization. Our case illustrates the importance of suspicion and complete examination of perianal masses. In practice, examination of the inguinal region should be a part of routine proctological examination.

Skin manifestation of mantle cell lymphoma – case report and literature review

“…W badaniu histopatologicznym rozpoznano chłoniaka z komórek płaszcza. Pacjent zmarł w 43. dobie po operacji z powodu narastających objawów niewydolności krą-żeniowo-oddechowej [12].…”

“…Based on histopathological findings, mantle cell lymphoma was diagnosed. The patient died from progressive cardiorespiratory failure 43 days after the surgery [12].…”

In situ diffuse large B‐cell lymphoma in haemorrhoidectomy tissue

“…Although gastrointestinal lymphoma is common, it is a rare malignancy in the anal margin and perianal skin. Only a few reports describe malignant lymphoma developing in external or internal haemorrhoids [ 1 , 2 ]. One case was a 33‐year‐old female who received haemorrhoidectomy which was diagnosed with B‐cell lymphoma.…”

“…This patient was still alive at the time of the report [ 1 ]. The other case was a 64‐year‐old man with a history of haemorrhoidal diseases, who developed a perianal mass mimicking an external thrombosed haemorrhoid in association with conglomerate inguinal lymph nodes, both tissues were diagnosed as mantle cell lymphoma [ 2 ]. This patient died of comorbidities after surgery [ 2 ].…”

“…Only a few reports describe malignant lymphoma developing in external or internal haemorrhoids [1,2]. One case was a 33-year-old female who received haemorrhoidectomy which was diagnosed with B-cell lymphoma.…”