Perfusion Lung Scintigraphy for the Prediction of Postlobectomy Residual Pulmonary Function

Giordano, Alessandro; Calcagni, Maria Lucia; Meduri, G; Valente, Salvatore; Galli, G

doi:10.1378/chest.111.6.1542

Cited by 59 publications

(33 citation statements)

References 8 publications

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“…Together, pulmonary emboli, anastomotic leaks, and respiratory failure account for 80 percent of all deaths in the first 30 days following bariatric surgery (Virji & Murr, 2006). As in this study the biodistribution of pertechnetate was higher in lungs of operated rats then in controls, the interpretation of eventual lung exams (Giordano et al, 1997) in patients has to be with caution. In the past five years, several confirmed cases of pancreatic disorders occurred in persons who had undergone bariatric surgery (Service et al, 2005).…”

Section: Discussionmentioning

confidence: 59%

Biodistribution of the radiopharmaceutical sodium pertechnetate after biliopancreatic bypass with a duodenal switch

Araújo‐Filho

Rêgo

Brandão-Neto

et al. 2007

Braz. arch. biol. technol.

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Section: Discussionmentioning

confidence: 59%

Biodistribution of the radiopharmaceutical sodium pertechnetate after biliopancreatic bypass with a duodenal switch

Araújo‐Filho

Rêgo

Brandão-Neto

et al. 2007

Braz. arch. biol. technol.

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“…To evaluate the functional respectability for lung cancer, the preoperative pulmonary function test is still the gold standard, and ppoFEV 1 is the most reliable predictor for mortality and morbidity [20] [50]. However, several approaches, such as inhalation perfusion (single-photon emission computed tomography) imaging [51], perfusion lung scintigraphy [52], and quantitative computed tomography [53] have been proposed for predicting precise postoperative FEV 1 . None of these methods has been proven to be more accurate than the simple calculation based on the number of removed bronchopulmonary segments [16].…”

Section: Discussionmentioning

confidence: 99%

Effect of Inhaled Tiotropium as the Perioperative Management of Patients Undergoing Pulmonary Resection for Primary Lung Cancer

Ayabe¹,

Tomita²,

Chosa³

et al. 2014

JCT

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Background: The purpose of this study was to evaluate the effectiveness of perioperative tiotropium therapy for patients undergoing pulmonary resection for primary lung cancer. The shortterm tiotropium effect was investigated by perioperative pulmonary function and "lung age". Methods: The fifty-five patients who underwent a lobectomy and had tiotropium treatment available from October 2007 through May 2009 were the subjects. The patients were divided into 3 groups according to their airway limitation such as Chronic Obstructive Pulmonary Disease (COPD) or a history of smoking; those with COPD (%FEV1 ≤ 70%, C-group, n = 22), smokers (%FEV 1 > 70%, S-group, n = 10) and non-smokers (%FEV 1 > 70%, N-group, n = 23). As the bronchodilator groups, the C-and S-groups received inhaled tiotropium bromide (18 μg once daily) for 1 week before surgery until at least 3 weeks after surgery without interruption, and as a control, the N-group had no treatment. The preoperative baselines, the predicted postoperative values, and the actual postoperative ones were measured by the pulmonary function test. The changed rates were calculated and denoted as ΔVC, ΔFEV 1 , ΔVC%, and ΔFEV 1 /FVC, from the baseline of the predicted postoperative values. The mean "real age" and "lung age" were calculated. Results: In the S-group, the parameters of ΔVC, ΔFEV 1 , ΔVC%, and ΔFEV 1 /FVC significantly increased compared to those of the N-group. In the C-group, the increased extents of ΔFEV 1 and ΔFEV 1 /FVC were lower compared to those in the S-group (not significant). In the N-group, the parameters of ΔVC, ΔFEV 1 , and ΔVC% decreased. The postoperative "lung age" and "real age" were increased to 29.5 ± 18.0 year-old in the C-group, 25.8 ± 18.0 in the S-group, and 24.7 ± 17.0 in the N-group. Lung resection affected the "lung age"; the aging was a 28.9 ± 12.7 year-old increase in the N-group. In the C-and S-group, the "lung age" was a 14-year-old increase. The effect of tiotropium treatment affected the "lung age" as * Corresponding author. T. Ayabe et al. 846a 15-year-old increase. Conclusion: Perioperative interventional tiotropium contributed to the lobectomy patients with COPD and for smokers with a non-obstructive airway and played a role of preserving the postoperative lung function.

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“…The four validated methods to predict postoperative lung function are: 1) anatomic calculation, 2) split radionuclide perfusion scanning, 3) quantitative computed tomography (CT) scanning, and 4) dynamic perfusion magnetic resonance imaging (MRI). Using these techniques, the actual lung function was consistently underestimated, particularly if the starting value was lower (Giordano, et al 1997;Zeiher, et al 1995). The accuracy of prediction of anatomic calculation is slightly lower than the other methods, but the other methods effectively predict postoperative FEV1 with similar accuracy.…”

Section: The Methods For Prediction Of Postoperative Lung Functionmentioning

confidence: 96%

“…A recent study using technetium scanning calculated values of imprecision from 18%-21% despite showing reasonable correlation (Giordano, et al 1997). …”

Section: Split Radionuclide Perfusion Scanningmentioning

confidence: 99%

Prediction of Postoperative Lung Function

Jang¹

2012

Topics in Cancer Survivorship

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Perfusion Lung Scintigraphy for the Prediction of Postlobectomy Residual Pulmonary Function

Cited by 59 publications

References 8 publications

Biodistribution of the radiopharmaceutical sodium pertechnetate after biliopancreatic bypass with a duodenal switch

Biodistribution of the radiopharmaceutical sodium pertechnetate after biliopancreatic bypass with a duodenal switch

Effect of Inhaled Tiotropium as the Perioperative Management of Patients Undergoing Pulmonary Resection for Primary Lung Cancer

Prediction of Postoperative Lung Function

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