2013
DOI: 10.1016/j.bbr.2013.01.027
|View full text |Cite
|
Sign up to set email alerts
|

Performance on a strategy set shifting task during adolescence in a genetic model of attention deficit/hyperactivity disorder: Methylphenidate vs. atomoxetine treatments

Abstract: Research examining medication effects on set shifting in teens with attention deficit/hyperactivity disorder (ADHD) is lacking. An animal model of ADHD may be useful for exploring this gap. The Spontaneously Hypertensive Rat (SHR) is a commonly used animal model of ADHD. SHR and two comparator strains, Wistar-Kyoto (WKY) and Wistar (WIS), were evaluated during adolescence in a strategy set shifting task under conditions of a 0-sec or 15-sec delay to reinforcer delivery. The task had three phases: initial discr… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

8
47
0

Year Published

2014
2014
2022
2022

Publication Types

Select...
6

Relationship

4
2

Authors

Journals

citations
Cited by 32 publications
(55 citation statements)
references
References 79 publications
8
47
0
Order By: Relevance
“…Strategy set shifting in adolescence 2.4.1 Habituation-An operant version of the strategy set shifting task was used [22,52]. On P28, WKY treated with vehicle (n=9) or d-amphetamine (n=9), WIS treated with vehicle (n=9) or d-amphetamine (n=9), and SHR treated with vehicle (n=10) or d-amphetamine (n=12), received 20 chocolate-flavored pellets in their home cages, to habituate rats to the novel food.…”
Section: Methodsmentioning
confidence: 99%
See 4 more Smart Citations
“…Strategy set shifting in adolescence 2.4.1 Habituation-An operant version of the strategy set shifting task was used [22,52]. On P28, WKY treated with vehicle (n=9) or d-amphetamine (n=9), WIS treated with vehicle (n=9) or d-amphetamine (n=9), and SHR treated with vehicle (n=10) or d-amphetamine (n=12), received 20 chocolate-flavored pellets in their home cages, to habituate rats to the novel food.…”
Section: Methodsmentioning
confidence: 99%
“…Rats were individually housed in plastic cages with Aspen bedding in a temperature-(21-23°C) and light-(07:30 hours on; 19:30 hours off) controlled vivarium]. From P28-P55, constituting the rat adolescent period [61], food was restricted to achieve ~90% of a growth-adjusted free-feeding body weight to facilitate lever responding for food reinforcement during the strategy set-shifting task, and to mimic conditions of past comparator studies [22,30,[33][34][35]62]. Animals had free access to water throughout experiments and to food after P55.…”
Section: Subjectsmentioning
confidence: 99%
See 3 more Smart Citations