Performance of d-amino acid oxidase in presence of ionic liquids

Ionic liquids as alternative co‐solvents for laccase: Study of enzyme activity and stability

“…In recent years, ILs have also been applied as solvents for biocatalysis: several studies have been published regarding the activity and the stability of proteins in ionic liquids (Diego et al, 2005;Fujita et al, 2005Fujita et al, , 2006Lau et al, 2004;Lozano et al, 2001;Park and Kazlauskas, 2003) and the performance of ILs as solvents for enzymatic reactions (Barahona et al, 2006;Baumann et al, 2005;Chiappe et al, 2007;Kragl et al, 2002;Lutz-Wahl et al, 2006;Sgalla et al, 2007). An excellent review has recently been published covering these issues (Rantwijk and Sheldon, 2007).…”

Applied Biocatalysis: An Overview

“…Not all ionic liquids have been found suitable for biocatalysis. Enzymes tend to retain catalytic activity in ionic liquids containing dimethylphosphate, tetrafl uoroborate (both water soluble), bis((trifl uoromethyl) -sulfonyl)imide, hexafl uorophosphate (both water insoluble), but not in ionic liquids containing Cl, NO 3 , CF 3 SO 3 , trifl uoroacetate, or acetate anions [106,107] . Whole cells have also been shown to retain activity in ionic liquids containing bis((trifl uoromethyl) -sulfonyl)imide, hexafl uorophosphate [83] .…”

“Nonsolvent” Applications of Ionic Liquids in Biotransformations and Organocatalysis

“…Since then, the use of ionic liquids as (co)solvents in biotransformations in combination with many enzymes, substrates, and processes has become an important topic of research. Examples include the use of lipases, [12c, 14] proteases, [12,15] glycosidases, [16] epoxide hydrolases, [17] oxidoreductases, [18] hydroxynitrile lyases, [19] peroxidases, [20] and even whole cells. [12b, 21] As the polarity of RTILs can also be modulated, they can be used as (co)solvents that are miscible with either water or organic solvents, or even in ternary systems (see Section 2.3).…”