Performance Improvement of Ring-Type PZT Ceramics for Ultrasonic Dispersion System

Choi, Young; Lee, Yang Lae; Lim, Eui Su; Trimzi, Mojiz Abbas; Hwangbo, Seon-Ae; Ham, Young-Bog

doi:10.3390/mi11020144

Cited by 9 publications

(8 citation statements)

References 26 publications

(27 reference statements)

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“…Focused ultrasound technology effectively utilizes ultrasound energy by focusing it at the center of a cylindrical piezoelectric ceramic [28]. Therefore, the energy distribution is more uniform than that of other ultrasonic equipment, such as bath or horn sonicators.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Uniform Nano Liposomes Using Focused Ultrasonic Technology

Yun,

Hwangbo,

Jeong

2023

Nanomaterials

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Liposomes are microspheres produced by placing phospholipids in aqueous solutions. Liposomes have the advantage of being able to encapsulate both hydrophilic and hydrophobic functional substances and are thus important mediators used in cosmetics and pharmaceuticals. It is important for liposomes to have small sizes, uniform particle size distribution, and long-term stability. Previously, liposomes have been prepared using a homo mixer, microfluidizer, and horn and bath types of sonicators. However, it is difficult to produce liposomes with small sizes and uniform particle size distribution using these methods. Therefore, we have developed a focused ultrasound method to produce nano-sized liposomes with better size control. In this study, the liposome solutions were prepared using the focused ultrasound method and conventional methods. The liposome solutions were characterized for their size distribution, stability, and morphology. Results showed that the liposome solution prepared using focused ultrasonic equipment had a uniform particle size distribution with an average size of 113.6 nm and a polydispersity index value of 0.124. Furthermore, the solution showed good stability in dynamic light scattering measurements for 4 d and Turbiscan measurements for 1 week.

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Section: Introductionmentioning

confidence: 99%

Preparation of Uniform Nano Liposomes Using Focused Ultrasonic Technology

Yun,

Hwangbo,

Jeong

2023

Nanomaterials

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“…Based on the converse piezoelectric effect, an ultrasonic transducer produces cavitation effects. In particular, lead zirconate titanate (Pb[Zr (1−x) Ti x ]O 3 or PZT) is a suitable material for ultrasonic transducers because of its high piezoelectric constant, relative transients, and electromagnetic binding factors [10]. Such lead-based complex perovskites have been extensively investigated from both the academic and commercial perspectives.…”

Section: Introductionmentioning

confidence: 99%

Influence of Piezoelectric Properties on the Ultrasonic Dispersion of TiO2 Nanoparticles in Aqueous Suspension

2021

Self Cite

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In this study, the soft-type and hard-type lead zirconate titanate (PZT) ceramics were compared in order to create an optimal system for ultrasonic dispersion of nanoparticles, and sound pressure energy for each PZT ceramic was analyzed and closely examined with ultrasonic energy. TiO2 was water-dispersed using the soft-type and hard-type PZT transducer, possessing different characteristics, and its suspension particle size and distribution, polydispersity index (PDI), zeta potential, and dispersion were evaluated for 180 days. Furthermore, it was confirmed that the particles dispersed using the hard-type PZT transducer were smaller than the particles dispersed using the soft-type PZT by 15 nm or more. Because the hard-type PZT transducer had a lower PDI, uniform particle size distribution was also confirmed. In addition, by measuring the zeta potential over time, it was found that the hard-type PZT transducer has higher dispersion safety. In addition, it was confirmed that the ultrasonically dispersed TiO2 suspension using a hard-type PZT transducer maintained constant particle size distribution for 180 days, whereas the suspension from the soft-type PZT aggregated 30 days later. Therefore, the hard-type PZT is more suitable for ultrasonic dispersion of nanoparticles.

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“…Therapeutic ultrasound can produce two types of biological effects, namely thermal and nonthermal effects. Lead zirconate titanate (PZT) ceramics for ultrasonic-induced nonthermal effects can be further classified into cavitation, acoustic streaming, acoustic torque, radiation force, and radiation pressure [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ]. These nonthermal phenomena are the result of attenuated ultrasound energy after ultrasound is absorbed by the biological tissues or scattering while traveling through biological tissues.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Cylindrical Piezoelectric and Specific Multi-Channel Circular MEMS-Transducer Array Resonator of Ultrasonic Ablation

2021

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Background: A cylindrical piezoelectric element and a specific multi-channel circular microelectromechanical systems (MEMS)-transducer array of ultrasonic system were used for ultrasonic energy generation and ablation. A relatively long time is required for the heat to be conducted to the target position. Ultrasound thermal therapy has great potential for treating deep hyperplastic tissues and tumors, such as breast cancer and liver tumors. Methods: Ultrasound ablation technology produces thermal energy by heating the surface of a target, and the heat gradually penetrates to the target’s interior. Beamforming was performed to observe energy distribution. A resonance method was used to generate ablation energy for verification. Energy was generated according to the coordinates of geometric graph positions to reach the ablation temperature. Results: The mean resonance frequency of Channels 1–8 was 2.5 MHz, and the cylindrical piezoelectric ultrasonic element of Channel A was 4.2546 Ω at 5.7946 MHz. High-intensity ultrasound has gradually been applied in clinical treatment. Widely adopted, ultrasonic hyperthermia involves the use of high-intensity ultrasound to heat tissues at 42–45 °C for 30–60 minutes. Conclusion: In the ultrasonic energy method, when the target position reaches a temperature that significantly reduces the cell viability (46.9 °C), protein surface modification occurs on the surface of the target.

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Performance Improvement of Ring-Type PZT Ceramics for Ultrasonic Dispersion System

Cited by 9 publications

References 26 publications

Preparation of Uniform Nano Liposomes Using Focused Ultrasonic Technology

Preparation of Uniform Nano Liposomes Using Focused Ultrasonic Technology

Influence of Piezoelectric Properties on the Ultrasonic Dispersion of TiO2 Nanoparticles in Aqueous Suspension

Investigation of Cylindrical Piezoelectric and Specific Multi-Channel Circular MEMS-Transducer Array Resonator of Ultrasonic Ablation

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