Performance Evaluation of Atenolol Molecular Imprinted Polymer Using Two Different Polymerization and Two Different Porogen

An Update on the Use of Molecularly Imprinted Polymers in Beta-Blocker Drug Analysis as a Selective Separation Method in Biological and Environmental Analysis

“…The bulk polymerization method is widely used to produce MIPs. The MIP is typically prepared by solution polymerization, followed by mechanical grinding of the resulting bulk polymer to produce small particles, which are then sieved into the necessary size ranges, typically in the micrometer range [62,63]. This method has many advantages, such as its simplicity, straightforward imprinting condition optimization [63], and the use of a small amount of porogenic solvent [62].…”

“…The molecularly imprinting technique using bulk polymerization has been developed to selectively extract atenolol, carvedilol, pindolol, and sotalol in serum and urine samples [62,[64][65][66][67][68]. Based on the study conducted by Gorbani et al, the MIP for the selective removal of atenolol in human urine samples was synthesized through the bulk polymerization method, with the MIP sorbent being synthesized using the non-covalent molecular imprinting approach.…”

Synthesis of molecularly imprinted polymer with a methacrylate derivative monomer for the isolation of ethyl p-methoxycinnamate as an active compound from Kaempferia galanga L. extracts

“…The adsorption capacity test was determined using an adsorption isotherm model that describes the characteristics of the MIP and calculates the relationship between the binding parameters and the affinity distribution. 63,64 Isotherm adsorption analysis was carried out using the Freundlich and Langmuir isotherm models. The adsorption capacity results show that the tested MIP and NIP polymers are better tted by the Freundlich isotherm model because the linearity value (R 2 ) of the Freundlich isotherm model is greater than that of the Langmuir isotherm model.…”

Synthesis and Characterization of Molecular Imprinted Polymers for Phenylbutazone Extraction

“…To test the retention of the resulting molecularly imprinted polymer (MIP), a molecular non-imprinted polymer (NIP) was created in the same manner but without the inclusion of phenylbutazone as a template. In terms of the deposition polymerization approach, NIP polymerization was carried out in a water bath shaker at 65°C for 24 hours (Suherman et al, 2018;Hasanah et al, 2019). The polymer was filtered and washed with methanol-chloroform (1:1) many times.…”

“…The most useful solvent is methanol:chloroform (1:1), which has the highest % adsorption value. Because the presence of chloroform reduces polarity, the hydrogen bonds produced are not overly disturbed (Hasanah et al, 2019).…”