Abstract:Approximately 10% of the global population identify themselves as
penicillin allergic, yet 90% are not truly allergic and could safely
tolerate penicillin. There is no simple way to identify these people.
Current in vitro diagnostics include specific immunoglobulin E
(with a sensitivity of 19% and specificity of 97%) and basophil
activation testing (BAT) with undefined sensitivity and specificity.
PubMed and EMBASE searched from inception to 03/05/2022 for original
studies evaluating the performance characteri… Show more
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