Perforating folliculitis with jaundice in an Indian male: a rare case with sclerosing cholangitis

Mahajan, Supriya; Koranne, R V; Sardana, Kabir; Mendiratta, Vibhu; Damani, A.

doi:10.1046/j.1365-2133.2004.05812.x

Cited by 13 publications

(11 citation statements)

References 12 publications

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“…It occurs mainly in patients with sever renal insufficiency, poorly controlled DM or arterial hypertension as well as in sclerosing cholangitis. Some researchers consider scratching to play a important role [9]. Others consider bile acids and their metabolites or vitamin A deficiency as possible causes [10].…”

Section: Discussionmentioning

confidence: 99%

Perforating folliculitis, angioedema, hand‐foot syndrome – multiple cutaneous side effects in a patient treated with sorafenib

Wolber

Udvardi

Tatzreiter

et al. 2009

J Deutsche Derma Gesell

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A patient with clear cell renal cell carcinoma was treated with sorafenib, a multikinase inhibitor, which induced a variety of cutaneous side effects. In addition to xerosis, he developed angioedema (AE), hand-foot syndrome (HFS) and perforating folliculitis (PF). The latter three occurred in a dose-dependent manner. AE was observed at the recommended daily dose of 800 mg. Dose reduction to 400 mg prevented its recurrence. At this dose level, the patient exhibited HFS, which cleared upon further reduction of the dose. While receiving 200 mg, the patient developed PF. To the best of our knowledge, this is the first description of a case of PF during treatment with sorafenib.

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Section: Discussionmentioning

confidence: 99%

Perforating folliculitis, angioedema, hand‐foot syndrome – multiple cutaneous side effects in a patient treated with sorafenib

Wolber

Udvardi

Tatzreiter

et al. 2009

J Deutsche Derma Gesell

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“…5 Entretanto, relatos com associação à hipertensão arterial sistêmica, ateroesclerose, psoríase, 3,4,9 tumores (incluíndo linfomas), 5 infecção pelo HIV, 4 insuficiência hepática crônica (colangite esclerosante) têm sido descritos. 3,7 Caracteriza-se pela presença de pápulas eritematosas com centro queratótico, pruriginosas, acometendo principalmente tronco e membros. 8,10 Os achados clínicos e histológicos são semelhantes aos das dermatoses perfurantes primárias, sendo que Rappini et al sugerem que a dermatose perfurante adquirida pode apresentar-se de diferentes maneiras, assemelhando-se histologicamente às quatro dermatoses perfurantes primárias, de forma isolada ou como combinação delas.…”

Section: Relato Do Casounclassified

“…Os casos relatados associados à insuficiência hepática são devidos à colangite esclerosante, sem tratamento com transplante de fígado. 3,7 Vários mecanismos patogênicos têm sido incriminados na dermatose perfurante adquirida (perfil foliculite perfurante), entre eles uma queratinização folicular precoce e/ou uma alteração primária do tecido conectivo, com depósito de material tipo corpo estranho na derme superficial e sua eliminação pelo epitélio proliferado (eliminação transepitelial). 3,8 Propõe-se que a intensa fricção causada pelo prurido colestático induza uma prematura hiperqueratinização folicular.…”

Section: Relato Do Casounclassified

“…A dermatose perfurante adquirida é entidade clinicopatológica caracterizada por eliminação transepitelial de material dérmico degenerado, [1][2][3][4] ocorrendo em muitas condições, entre elas diabetes mellitus, insuficiência renal crônica e doenças hepáticas, incluindo colangite esclerosante. 3,5 Hepatopatias graves, como colangite esclerosante, e distúrbios metabólicos hereditários, como a glicogenose tipo I, são indicações de transplante hepático. 6 A descrição da dermatose perfurante adquirida associada à insuficiência hepática foi previamente relatada em casos de colangite esclerosante, sem transplante hepático como tratamento.…”

Section: Introductionunclassified

“…6 A descrição da dermatose perfurante adquirida associada à insuficiência hepática foi previamente relatada em casos de colangite esclerosante, sem transplante hepático como tratamento. 3,7…”

Section: Introductionunclassified

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Dermatose perfurante adquirida associada à insuficiência hepática em paciente transplantado de fígado

Badziak¹,

Lenhardt

Barros

et al. 2007

An. Bras. Dermatol.

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A dermatose perfurante adquirida é entidade clinicopatológica caracterizada por eliminação transepitelial de material dérmico degenerado, ocorrendo em muitas condições, entre elas diabetes mellitus, insuficiência renal crônica e colangite esclerosante. Relata-se o caso de paciente de 17 anos, com dermatose perfurante adquirida associada à insuficiência hepática crônica, conseqüente à complicação hepática de transplante de fígado para tratamento de sua doença de base, a glicogenose tipo I.

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Primary Biliary Cholangitis Associated with Skin Disorders: A Case Report and Review of the Literature

Beretta‐Piccoli

Guillod

Marsteller

et al. 2017

Arch. Immunol. Ther. Exp.

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Primary biliary cholangitis (PBC) is a rare autoimmune cholestatic liver disease. It is often associated with extrahepatic autoimmune diseases. Skin disorders are sporadically reported in association with PBC. We report an unusual case of PBC associated with acquired reactive perforating dermatosis (ARPD) and present a review of the literature on skin disorders associated with PBC. Our patient presented to the dermatology department with generalized pruritus associated with nodular perforating skin lesions on the trunk, and cholestatic liver disease of unknown origin. After having established both diagnosis of ARPD and PBC, she was managed in an interdisciplinary manner, and both her skin and liver conditions improved gradually. Only one similar case is reported in the literature, in that case, the liver disease was not treated. By reviewing the literature, we found that lichen planus, vitiligo, and psoriasis are the most frequent skin disorders associated with PBC. However, there is only limited data about specific skin disorders associated with PBC. This case report of a patient with PBC associated with ARPD underlines the importance of interdisciplinary management of patients with rare liver diseases combined with rare skin disorders. The present review of the literature shows that probably, immune-mediated skin conditions are not more frequent in PBC patients than in the general population. However, the available data are scant; there is a need for high-quality data on skin conditions associated with PBC.

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Perforating folliculitis with jaundice in an Indian male: a rare case with sclerosing cholangitis

Cited by 13 publications

References 12 publications

Perforating folliculitis, angioedema, hand‐foot syndrome – multiple cutaneous side effects in a patient treated with sorafenib

Perforating folliculitis, angioedema, hand‐foot syndrome – multiple cutaneous side effects in a patient treated with sorafenib

Dermatose perfurante adquirida associada à insuficiência hepática em paciente transplantado de fígado

Primary Biliary Cholangitis Associated with Skin Disorders: A Case Report and Review of the Literature

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