Dermatose perfurante adquirida associada à insuficiência hepática em paciente transplantado de fígado

Badziak, Daniela; Lenhardt, Carolina; Barros, Michele F. de; Mandelli, F; Serafini, Sérgio Zuñeda; Santamaria, Jesus Rodriguez

doi:10.1590/s0365-05962007000100007

Cited by 5 publications

(6 citation statements)

References 14 publications

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“…Perforating dermatoses are a group of disorders characterized by transepidermal elimination of dermal material. 1 They are divided into primary (or classic) and secondary forms. 1 Primary perforating dermatoses are subdivided into Kyrle disease (KD), reactive perforating collagenosis (RPC), perforating serpiginous elastosis (PSE), and perforating folliculitis (PF), according to the eliminated dermal material.…”

Section: Introductionmentioning

confidence: 99%

“… 1 They are divided into primary (or classic) and secondary forms. 1 Primary perforating dermatoses are subdivided into Kyrle disease (KD), reactive perforating collagenosis (RPC), perforating serpiginous elastosis (PSE), and perforating folliculitis (PF), according to the eliminated dermal material. 2 The elimination of cellular debris without collagen or elastic fibers is seen in KD; RPC eliminates only collagen fibers; EPS eliminates only elastic fibers; PF eliminates damaged hair follicles.…”

Section: Introductionmentioning

confidence: 99%

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Acquired perforating dermatosis in a patient with chronic renal failure

Fernandes

Lima²,

Guedes

et al. 2016

An. Bras. Dermatol.

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Perforating dermatoses are a group of skin diseases characterized by transepidermal elimination of dermal material. The disease is divided into two groups: the primary group and the secondary group. The classical or primary perforating dermatoses are subdivided into four types according to the eliminated dermal materials: Kyrle disease, perforating reactive collagenosis, elastosis perforans serpiginosa, and perforating folliculitis. The secondary form is known as acquired perforating dermatosis. The term was proposed in 1989 by Rapini to designate the perforating dermatoses affecting adult patients with systemic disease, regardless of the dermal materials eliminated. This report describes a case of the disease with elimination of collagen and elastic fibers in a patient with chronic renal failure.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Acquired perforating dermatosis in a patient with chronic renal failure

Fernandes

Lima²,

Guedes

et al. 2016

An. Bras. Dermatol.

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“…3 More recent publications have described its association with other systemic diseases such as tumors, chronic hepathopathies and HIV, among others. 4,5 It is characterized by the presence of erythematous papules with a hyperkeratotic center, pruritic, mainly located in the trunk and limbs.…”

Section: Discussionmentioning

confidence: 99%

Caso para diagnóstico

Silva

Miltersteiner

Burmeister

et al. 2011

An. Bras. Dermatol.

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Dermatose perfurante adquirida é uma condição rara, em geral associada a algumas doenças sistêmicas, ocorrendo especialmente em pacientes diabéticos com insuficiência renal crônica submetidos a diálise. O sintoma principal é o prurido e a apresentação clínica característica é a presença de lesões papulares marrom-avermelhadas no tronco, cabeça e pescoço. Biópsia da lesão revela invaginação epidérmica com preenchimento por plug ceratótico. A etiologia é pouco compreendida e várias tentativas terapêuticas têm sido desapontadoras.

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“…Acquired reactive perforating collagenosis (ARPC) is a unique skin disease belonging to the group of perforating dermatoses, which are characterized by transepidermal elimination of dermal material such as collagen, elastin, or fibrin (1). These perforating dermatoses may be subdivided based on the eliminated dermal material and include Kyrle disease, elastosis perforans serpiginosa, perforating folliculitis, and acquired reactive perforating collagenosis.…”

Section: Introductionmentioning

confidence: 99%

Pruritic Rash in an Elderly Patient with Uncontrolled Diabetes Mellitus

Bartling

Naff

Canevari

et al. 2019

AACE Clinical Case Reports

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Objective: Acquired reactive perforating collagenosis is an uncommon skin disease that belongs to a group of dermatologic disorders characterized by transepidermal elimination of dermal material. It is highly associated with systemic disease, primarily diabetes mellitus and dialysisdependent chronic renal failure. Methods: A 70-year-old female with 20 years of poorly controlled type 2 diabetes mellitus presented with a 6-month history of multiple pruritic erythematous papules and nodules with central hyperkeratosis, involving her right dorsal arm. Histologic examination was consistent with acquired reactive perforating collagenosis. In addition to topical treatment of the disease, the patient was referred to endocrinology for appropriate management of her underlying diabetes mellitus. Results: Ideal treatment should involve both the endocrinologist and dermatologist. Control of the underlying systemic disease, in this case diabetes, as well topical or systemic medications can both help to improve this condition. Our patient re-established care with her endocrinologist who adjusted her medication regimen, resulting in improved hemoglobin A1c values. Our patient additionally benefited from topical betamethasone cream, ammonium lactate, and pimecrolimus application. The combined therapy led to resolution of her pruritic rash. Conclusion: This case highlights the importance of the skin exam by the endocrinologist, as he or she plays a unique role in identifying this rare and difficult-to-treat dermatologic disease. Early detection and prompt referral to a dermatologist are crucial in preventing progression of disease, treating the disease, and improving the patient's quality of life. (AACE Clinical Case Rep.

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Dermatose perfurante adquirida associada à insuficiência hepática em paciente transplantado de fígado

Cited by 5 publications

References 14 publications

Acquired perforating dermatosis in a patient with chronic renal failure

Acquired perforating dermatosis in a patient with chronic renal failure

Caso para diagnóstico

Pruritic Rash in an Elderly Patient with Uncontrolled Diabetes Mellitus

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