Perforating and non-perforating indications for repeated operations in Crohn's disease: evidence for two clinical forms.

Greenstein, Adrian J.; Lachman, Prem; Sachar, David B.; Springhorn, J; Heimann, Tomas M.; Janowitz, Henry D.; Aufses, Arthur H.

doi:10.1136/gut.29.5.588

Cited by 385 publications

(156 citation statements)

References 6 publications

(1 reference statement)

Supporting

Mentioning

138

Contrasting

Unclassified

Order By: Relevance

“…In a previous study from our group we evaluated patients with active fistulizing Crohn's disease and we found a high frequency (50%) of ileocolic disease among them (10) . This finding has been described by other authors (3,6) . It is still believed that involvement of the small intestine and upper gastrointestinal tract is more common in subjects diagnosed under the age of 20 years while the colonic disease is frequently diagnosed in patients over the age of 60 years (4) .…”

Section: Resultssupporting

confidence: 79%

“…At the present study, most patients had ileocolic disease (38.8%), in contrast to the original publication of Vienna where the colonic location was more prevalent with 35.8% of the patients been classified as L2 (5) . Another study from a tertiary center also showed a higher frequency of ileocolic location (37.0%) (15) , reinforcing these findings and from others investigations (6,9) . Among the additional information collected for the classification the low frequency of patients with a family history of Crohn's disease may be explained by the difficulty in analyzing this variable since many patients do not have this information about their family members or perhaps the disease is misdiagnosed.…”

Section: Resultssupporting

confidence: 74%

“…There are reports about the association of the disease restricted to the ileum (L1) to the stricturing disease (B2), however in our study we did not detect this association in any of the patients (6) . This might be explained by the small number of cases or by the fact that our service has a clinical and not a surgical profile.…”

Section: Resultscontrasting

confidence: 54%

See 2 more Smart Citations

Application of the Vienna classification for Crohn’s disease to a single center from Brazil

Santana

Souza

Azevedo

et al. 2008

Arq. Gastroenterol.

View full text Add to dashboard Cite

BACKGROUND: Crohn’s disease is a chronic inflammatory disorder with diversity on its clinical presentation that may be observed from the varying age of onset of symptoms to the site of occurrence of the illness. There is a need for a replicable and uniform description of the disease allowing a comparison between distinct study populations. The 1998 Vienna classification characterizes patients according to three clinical aspects: age at diagnosis, location and disease behavior. AIM: To describe Crohn’s disease in patients from a reference center of Salvador, BA, Brazil according to the Vienna classification. METHODS: Between January and October of 2005, patients (n = 47) having at least one endoscopic and radiological examination of the intestine participated in this study. RESULTS: Most of the participants had the diagnosis of the disease when they were younger than 40 years old (70.2%) while an ileocolic location (38.3%) and the penetrating form (46.8%) were the most prevalent clinical presentation. The restricted location of the ileum (L1) was more frequent in nonstricturing, nonpenetrating disease (B1) while the ileocolic disease (L3) was more associated with the penetrating behavior (B3). CONCLUSION: In this study, differently from the first description of the Vienna classification, the large number of patients presenting a complicated stage of the disease can be attributed to the fact that it was carried out at a reference center, where many patients present with the disease at an advanced stage.

show abstract

Section: Resultssupporting

confidence: 79%

Section: Resultssupporting

confidence: 74%

See 1 more Smart Citation

Application of the Vienna classification for Crohn’s disease to a single center from Brazil

Santana

Souza

Azevedo

et al. 2008

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

“…69,281 It is argued that administration of anti-mycobacterial therapy to those CD patients who do not belong to the group with a mycobacterial aetiology would mask this relationship, which assumes that the therapeutic agents are specific for mycobacteria, in particular M . paratuberculosis or the MA1 complex.…”

Section: Eficacy Of Anti-mycobacterial Drugs Against the Mai Complexmentioning

confidence: 99%

The role of mycobacteria in Crohn's disease

Thompson¹

1994

Journal of Medical Microbiology

View full text Add to dashboard Cite

“…4 Penetrating CD, defined as subacute perforation with abscess formation and chronic perforation with internal fistula formation, is still a prominent indication for surgery. 5 Patients who had abdominal surgery for penetrating CD still experience a high rate of post-operative complications. 6,7 A two-stage procedure including a temporary diverting stoma is often required in up to 39-51% of patients.…”

Section: Introductionmentioning

confidence: 99%

Pre‐operative management is associated with low rate of post‐operative morbidity in penetrating Crohn’s disease

Zerbib

Koriche

Truant

et al. 2010

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

Perforating and non-perforating indications for repeated operations in Crohn's disease: evidence for two clinical forms.

Cited by 385 publications

References 6 publications

Application of the Vienna classification for Crohn’s disease to a single center from Brazil

Application of the Vienna classification for Crohn’s disease to a single center from Brazil

The role of mycobacteria in Crohn's disease

Pre‐operative management is associated with low rate of post‐operative morbidity in penetrating Crohn’s disease

Contact Info

Product

Resources

About