Perfil fitoquímico e avaliação da atividade antimicrobiana de extratos aquoso e
            etanólico de folhas de Cecropia pachystachya

Costa, J.; Hoscheid, Jaqueline

doi:10.5935/2446-4775.20180016

Cited by 12 publications

(15 citation statements)

References 29 publications

(29 reference statements)

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“…A study evaluating the antimicrobial activity of the aqueous and alcoholic extracts of C. pachystachya leaves against S. aureus showed an inhibition zone of 7 mm for the alcoholic extract (at 100 mg mL -1 ) (Costa & Hoscheid, 2018). This inhibitory action was attributed to flavonoids and TPC, since they are well established as antimicrobial agents (Babii et al, 2016;Tsou et al, 2016;Echeverrí a et al, 2017).…”

Section: Total Phenolic Content Antibacterial and Antioxidant Activitymentioning

confidence: 99%

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Hoscheid

Otênio

Lourenço

et al. 2020

JAS

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Cecropia pachystachya Trécul is popularly known in Brazil as embaúva or embaúba. Pharmacological activities were reported in extant studies including the development of anxiolytic, antidepressant, hypoglycemic, antioxidant, cardiotonic, sedative, anti-inflammatory, antimicrobial and leishmanicidal properties for aqueous and alcoholic extracts prepared by infusion or maceration of C. pachystachya leaves. However, there is a paucity of studies examining extracts of leaves of C. pachystachya obtained by supercritical fluid technology. This study evaluated the extraction of Cecropia pachystachya oil using supercritical carbon dioxide (CO2). Extractions were performed at 35 °C, 45 °C, and 55 °C and 14 MPa, 17 MPa, and 20 MPa. The extraction yield, characteristics of the oil, antioxidant and antibacterial potentials were evaluated. The highest extraction yield obtained from C. pachystachya leaves was 1.48% using supercritical CO2 at 55 °C and 20 MPa. The main identified compounds include terpenoids (ursolic and pomolic acids, squalene and β-sitosterol). The most promising results for antibacterial activity relative to Staphylococcus aureus and antioxidant potentials were observed on the extract obtained at 55 °C and 14 MPa. The mathematical Sovová model satisfactorily represented the experimental data.

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Section: Total Phenolic Content Antibacterial and Antioxidant Activitymentioning

confidence: 99%

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Hoscheid

Otênio

Lourenço

et al. 2020

JAS

Self Cite

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“…In case there are no studies of certain species and their secondary metabolites, preliminary phytochemical screening acts as an identification method of several classes of primary and secondary metabolites. This process may be carried out by distinct methods and solvents, which lead to consequent high diversity of results (Costa & Hoscheid, 2018).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening of extracts from Spiranthera odoratissima A. St.-Hil. (Rutaceae) leaves and their in vitro antioxidant and anti-Listeria monocytogenes activities

Souza

Bessa

Fernandes

et al. 2020

Acta Sci. Biol. Sci.

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Spiranthera odoratissima A. St.-Hil (Rutaceae), a shrub whose common name is manacá do Cerrado in Brazilian Portuguese, is about 1-m high and has been used by folk medicine to treat stomachache, kidney and liver infections, headache, rheumatism and as a blood purifier. This study aimed at preparing hexane, ethyl acetate, methanolic, hydroethanolic and aqueous extracts from S. odoratissima leaves, at carrying out preliminary phytochemical screening and at evaluating their in vitro antioxidant and anti-Listeria monocytogenes activities. Antioxidant activity was evaluated by the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azinobis-3-ethybenzothiazoline-6-sulfonate) and FRAP (ferric reducing antioxidant power) methods. Antibacterial activity was investigated against L. monocytogenes and Minimum Inhibitory Concentration (MIC) values of plant extracts were calculated by the broth microdilution method with the use of 96-well plates. In aqueous, methanolic, hydroethanolic, ethyl acetate and hexane extracts from S. odoratissima leaves, the following classes of compounds were investigated: organic acids, reducing sugars, flavonoids, saponin compounds, coumarin compounds, phenolics, tannins, purine compounds, catechins, flavonol derivatives, sesquiterpene lactones and anthraquinones. All plant extracts, except the hexane one, exhibited high antioxidant activity. Regarding antibacterial activity, the most polar extracts showed high activity against L. monocytogenes; their MIC values ranged between 12.5 and 62.5 µg mL-1, while the hexane one exhibited low activity (MIC = 1000 µg mL-1). In short, extracts from S. odoratissima leaves may be considered promising sources of secondary metabolites with relevant antioxidant and antibacterial activities.

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“…In contraposition, Silva et al, (2012) showed that the methanolic extract of the leaves of S. tuberosa had MIC of 125 μg/mL and zone of inhibition of 20.1 mm against P. aeruginosa, however, it is noteworthy that different solvents have distinct selectivity, resulting in unequal bioactivities with a same vegetable, due to the difference of the extracted components (Costa & Hoscheid, 2018).…”

Section: 3 4 5 6 2 3 4 5 6 3 Results and Discussionmentioning

confidence: 99%

Antibacterial and antioxidant potential of Spondias tuberosa Arruda (Anacardiaceae) extracts

Santos

Carneiro

Andrade-Pinheiro

et al. 2020

RSD

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Antimicrobial resistance and the consequent inefficiency of antibiotics are the main problems faced by medicine. In view of this, numerous researches have been aimed at looking for new agents with antibacterial activity, among them natural products. Thus, this study aims to evaluate the antioxidant activity of aqueous and hydroalcoholic extracts of the leaves and roots of Spondias tuberosa by Thin Layer Chromatography (TLC), as well as to verify the antibacterial action of the extracts alone and in combination with commercial antibiotics to evaluate its potential in action of change of antibiotics. The extracts showed polar and nonpolar phenolic substances with antioxidant action. The Minimum Inhibitory Concentration (MIC) of the hydroalcoholic extracts of the leaves and roots was 1,024 μg/mL compared to the Staphylococcus aureus 25923 strain, whereas with the other strains, the products showed an MIC ≥ 2,048 µg/mL. The effect of combining extracts with amikacin, ampicillin and norfloxacin against the multidrug-resistant bacteria Escherichia coli 06, Staphylococcus aureus 10 and Pseudomonas aeruginosa 24 resulted in synergistic effects with aminoglycoside alone, achieving up to 75 % reduction in the MIC of the antibiotic. In view of the results obtained, it can be concluded that the extracts of S. tuberosa presented polar and nonpolar phenolic substances, in the antibacterial activity it can positively modify the effect of the aminoglycoside antibiotic against multi-resistant bacteria, but future studies are necessary to discover the mechanism of action of such an effect.

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Perfil fitoquímico e avaliação da atividade antimicrobiana de extratos aquoso e etanólico de folhas de Cecropia pachystachya

Cited by 12 publications

References 29 publications

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Phytochemical screening of extracts from Spiranthera odoratissima A. St.-Hil. (Rutaceae) leaves and their in vitro antioxidant and anti-Listeria monocytogenes activities

Antibacterial and antioxidant potential of Spondias tuberosa Arruda (Anacardiaceae) extracts

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