Perfil epidemiológico de neoplasias epiteliales de glándulas salivales

Abstract

Perfil epidemiológico de neoplasias epiteliales de glándulas salivales anDrés CamPolo gonzález 1 , hernán ramírez skinner 1 , alex vargas Díaz 1 , augusto león ramírez 1 , ignaCio goñi esPilDora 1 , antonieta solar gonzález 2 Epithelial tumors of salivary glands. Review of 286 pathology reports Background: Epithelial tumors of the salivary glands, including benign tumors and aggressive malignancies with different prognoses, are uncommon. Aim: To describe the frequency and distribution of salivary gland tumors according to age, gender and anatomical location. Material and Methods: Review of pathological reports of salivary gland tumors of a Pathology laboratory at a clinical hospital from 2006 to 2016. Results: Five hundred ninety salivary gland biopsies were reviewed. Of these, 286 (49%) were primary epithelial tumors of the salivary glands. Two hundred thirty (80%) were benign and 56 (20%) were malignant tumors. Regarding location, 274 (96%) were in the major salivary glands, and 12 (4%) in the minor salivary glands. The most common histological types were pleomorphic adenoma for benign tumors in 172 cases, followed by papillary cystadenoma lymphomatosum in 33 cases. Mucoepidermoid carcinoma was the most common malignant tumor in 14 cases. Conclusions: These results are similar to reports from abroad, however more studies are necessary to be able to establish a more representative and updated analysis.

Intra-Cystic (In Situ) Mucoepidermoid Carcinoma: A Clinico-Pathological Study of 14 Cases

“…MEC is the most common malignant tumor of the salivary glands (12%-29%) in children and young adults [9,25,28,29], and according to some authors, the most common malignancy in minor salivary glands [8][9][10][11][12][13]20]; its peak incidence is between the third and sixth decade, with predilection for females [25,28,29]. As confirmed by the results of the present study, the palate remains the most common site for MECs occurring in minor salivary glands, while they less frequently occur in the retromolar area, the floor of the mouth, the buccal mucosa, the lips and the tongue [3,5,18,23].…”

“…MEC is one of the most common salivary gland malignancies, showing distinctive morphological features, such as mucous, intermediate and epidermoid cells in variable proportions [5][6][7]. Less than half of the cases arise in minor salivary glands, the palate being the most common intra-oral localization of MEC [8][9][10][11][12]. The architectural configuration of MEC may vary, but a cystic component is commonly present and may sometimes predominate [5,6,[13][14][15].…”

“…Though considered a tumor with low malignant potential in most instances, about 10% of the patients affected by MEC experience tumor-related death [10,11,18,19]. In this regard, MECs located in the submandibular gland and those showing a high histopathologic grade are considered more aggressive [8][9][10]20,21].…”

Epidemiological profile of salivary gland lesions diagnosed in a higher education institution: an observational and retrospective study of 381 cases

“…Epidemiological studies are essential because nutritional factors, habits, geographical position and socioeconomic status of a population considerably influence the incidence of oral diseases. In the literature, SGL have a high prevalence (Moreira, et al, 2009;Campolo González et al, 2018;Silva et al, 2018;Neville etal., 2016), which was consistent with the findings of this study, in which 12.1% of all biopsied cases were SGL.…”

“…The prevalence of salivary gland lesions (SGL) varies worldwide. In a study on neoplastic SGL, Campolo González et al (2018) found that 49% were primary salivary gland tumors, of which 80% were benign and 20% malignant. Hill (2002) studied 135 salivary gland tumors and noted that there were differences in prevalence between these lesions, depending on the anatomical site.…”