Perfectionism underlying psychological background correlated with the symptoms of functional dyspepsia

Ochi, Masahiro; Tominaga, Kazunari; Iketani, Toshiya; Kadouchi, Kaori; Tanigawa, Tetsuya; Shiba, Masatsugu; Watanabe, Toshio; Fujiwara, Yasuhiro; Oshitani, Nobuhide; Higuchi, Kazuhide; Kiriike, Nobuo; Arakawa, Tetsuo

doi:10.1007/s00535-008-2210-9

Cited by 23 publications

(14 citation statements)

References 24 publications

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“…Lastly, familial factors may include psychological, environmental or genetic factors, which may contribute to abdominal symptoms of FD patients. Ahn et al90 found that family function score was lower in an FD group than in a normal control group, and Ochi et al91 suggested that parental criticism experienced in early life may underlie the psychological background of FD patients and correlated with their abdominal symptoms. All these results add support to the theory of psychosocial disturbances in the pathogenesis of FD.…”

Section: Consensus Statementsmentioning

confidence: 99%

Asian Consensus Report on Functional Dyspepsia

Miwa¹,

Ghoshal²,

Gonlachanvit³

et al. 2012

J Neurogastroenterol Motil

120

138

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Background/AimsEnvironmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared to the West, and physiological functions and genetic factors of Asians may also be different from those of Westerners. Establishing an Asian consensus for functional dyspepsia is crucial in order to attract attention to such data from Asian countries, to articulate the experience and views of Asian experts, and to provide a relevant guide on management of functional dyspepsia for primary care physicians working in Asia.MethodsConsensus team members were selected from Asian experts and consensus development was carried out using a modified Delphi method. Consensus teams collected published papers on functional dyspepsia especially from Asia and developed candidate consensus statements based on the generated clinical questions. At the first face-to-face meeting, each statement was reviewed and e-mail voting was done twice. At the second face-to-face meeting, final voting on each statement was done using keypad voting system. A grade of evidence and a strength of recommendation were applied to each statement according to the method of the GRADE Working Group.ResultsTwenty-nine consensus statements were finalized, including 7 for definition and diagnosis, 5 for epidemiology, 9 for pathophysiology and 8 for management. Algorithms for diagnosis and management of functional dyspepsia were added.ConclusionsThis consensus developed by Asian experts shows distinctive features of functional dyspepsia in Asia and will provide a guide to the diagnosis and management of functional dyspepsia for Asian primary care physicians.

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Section: Consensus Statementsmentioning

confidence: 99%

Asian Consensus Report on Functional Dyspepsia

Miwa¹,

Ghoshal²,

Gonlachanvit³

et al. 2012

J Neurogastroenterol Motil

120

138

View full text Add to dashboard Cite

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“…Therefore, patients in either subgroup may be easily differentiated according to their respective symptoms. Furthermore, similar to the pathophysiology of FGIDs, the pathophysiology of FD is related to symptoms characterized by multifunctional disorders of the upper GI tract, such as disorders of GI motility (4), abnormal acid secretion (5), visceral hypersensitivity (6), Helicobacter pylori (H. pylori) infection (7,8), potent psychological factors (9,10) and an imbalance of the autonomic nervous system (ANS) (11). The above dysfunctions indicate that each pathophysiological factor is directly associated with the four symptoms of FD; thus, distinct differences may exist in pathophysiology between the two subgroups.…”

Section: Introductionmentioning

confidence: 99%

Clinical Classification of Subgroups According to the Rome III Criteria Cannot be Used to Distinguish the Associated Respective Pathophysiology in Japanese Patients with Functional Dyspepsia

et al. 2013

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Objective Patients who meet the Rome III criteria for functional dyspepsia (FD) are generally classified into the following two subgroups, those with postprandial distress syndrome (PDS) and those with epigastric pain syndrome (EPS), in order to treat the dyspeptic symptoms caused by the respective pathophysiological conditions. However, whether simple classification of FD can accurately distinguish the pathophysiological differences between PDS and EPS remains to be clarified because the pathophysiology of FD is characterized and complicated by various factors. Methods After classifying FD patients who were not receiving medication at the initial visit, we assessed and compared the following pathophysiological factors between the PDS and EPS groups: (1) the gastric reservoir and emptying functions using a radioisotope method (n=75), (2) the autonomic nervous system (ANS) function using electrocardiography (n=45), (3) gastric mucosal atrophy and intestinal metaplasia using histological examinations (n=47), (4) endoscopic findings of the stomach, such as superficial changes, abnormal gastroesophageal flap valves (n=67) and (5) Helicobacter pylori infection (n=48). Results The FD patients exhibited higher rates of an impaired reservoir function (49.3%), gastric emptying disorders (54.7%) and relative hyperactivity of the sympathetic nervous system (31.9%) than the control subjects. However, endoscopic and histological changes of the stomach were similar in both the FD patients and control subjects. In addition, no differences were observed in the above-mentioned factors between the PDS and EPS groups. Conclusion The simple classification of FD patients into two subgroups according to the Rome III criteria following diagnosis does not indicate any differences in the pathophysiology related to the respective dyspeptic symptoms of FD patients.

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“…Clinical reports have provided evidence of the association between stress and FD pathogenesis, including gastric dysmotility [33][34][35]. Indeed, basic and clinical studies have shown that acute and chronic mental/physical stresses affect sensorimotor dysfunction of the gastrointestinal tract via various mediators including catecholamine, CRF, and ghrelin in rats [36][37][38][39] and humans [31,40,41].…”

Section: Discussionmentioning

confidence: 99%

Structural changes in gastric glial cells and delayed gastric emptying as responses to early life stress and acute adulthood stress in rats

et al. 2016

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Perfectionism underlying psychological background correlated with the symptoms of functional dyspepsia

Abstract: Perfectionism such as PC underlying the psychological background of FD patients may be correlated with their abdominal symptoms.

Cited by 23 publications

References 24 publications

Asian Consensus Report on Functional Dyspepsia

Asian Consensus Report on Functional Dyspepsia

Clinical Classification of Subgroups According to the Rome III Criteria Cannot be Used to Distinguish the Associated Respective Pathophysiology in Japanese Patients with Functional Dyspepsia

Structural changes in gastric glial cells and delayed gastric emptying as responses to early life stress and acute adulthood stress in rats

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