Percutaneous tibial nerve stimulation produces effects on brain activity: Study on the modifications of the long latency somatosensory evoked potentials

Abstract

The P80 and P100 amplitude increase might reflect long-term modifications in synaptic efficiency through the somatosensory pathway. The plastic reorganization of cortical network triggered by peripheral neuromodulation can be hypothesized as a mechanism of action of PTNS. Further studies are needed to correlate LL-SEP modifications after PTNS with the success of the treatment.

Urodynamic Effect of Percutaneous Posterior Tibial Nerve Stimulation for Urinary Incontinence in Paraparetic Patients

“…In the disagreement with the results of the present study, Zhao and Nordling [37] demonstrated that applying PTNS in patients with interstitial cystitis had no significant clinical effect otherwise the noticeable response could appear through stimulation of sacral root itself. Fjorback et al [38] also reported that PTNS showed no effect or failed to suppress detrusor contraction in patients with neurological detrusal overactivity, but there was an increase in the cyctometric bladder capacity and bladder volume during the first contraction after PTNS application.…”

Management of overactive bladder review: the role of percutaneous tibial nerve stimulation

“…When compared to sham procedure, the number or percentage of responders in PTNS group were statistically higher (p<0.01), not only in objective responses [32][33][34] but also in global response assessment (GRA) improvement or cure. 35 The significant reduction of symptoms in PTNS group compared to sham group were found in frequency, urinary incontinence, and nocturia episodes.…”

Effects of percutaneous posterior tibial nerve stimulation on voiding dysfunctions in cerebral palsy: A case report

“…The sacral micturition center and Onuf's nucleus are most probably areas where the therapeutic effect of neuromodulation of the bladder, by PTNS, take place [12]. PTNS effects are mediated by supra sacral centers of stimulus elaboration involving finally cortical associative areas [14]. TPTNS seems to regulate the activity of the bladder and urethra through facilitating voiding reflex, increases the contraction of the detrusor and relaxes sphincter and pelvic floor muscles [13,15].…”