2015
DOI: 10.1001/jamaoto.2015.0596
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Percutaneous Ethanol Injection vs Reoperation for Locally Recurrent Papillary Thyroid Cancer

Abstract: High-quality, well-designed studies are needed to evaluate the feasibility of incorporating PEI into the treatment protocol of PTC. Although presently inferior to reoperation, PEI has the potential to be a widely accepted and effective nonsurgical treatment option for limited recurrent PTC in poor surgical candidates or patients seeking to avoid multiple reoperations.

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Cited by 53 publications
(37 citation statements)
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“…5358 In addition, high-intensity focused ultrasound has been used for ablation of benign thyroid nodules and may have potential for use in DTC. 59,60 However, these techniques are outside the scope of this article and should only be used as an alternative to EBRT in highly selected cases.…”
Section: Recommendationsmentioning
confidence: 99%
See 1 more Smart Citation
“…5358 In addition, high-intensity focused ultrasound has been used for ablation of benign thyroid nodules and may have potential for use in DTC. 59,60 However, these techniques are outside the scope of this article and should only be used as an alternative to EBRT in highly selected cases.…”
Section: Recommendationsmentioning
confidence: 99%
“…[50][51][52] Several recent publications show promise for using other focal therapies such as radiofrequency ablation or percutaneous ethanol injection for locoregional recurrence of DTC. [53][54][55][56][57][58] In addition, high-intensity focused ultrasound has been used for ablation of benign thyroid nodules and may have potential for use in DTC. 59,60 However, these techniques are outside the scope of this article and should only be used as an alternative to EBRT in highly selected cases.…”
Section: Combination Of External-beam Radiotherapy With Other Therapiesmentioning
confidence: 99%
“…Meta‐analysis of the results of percutaneous ethanol versus surgery for locally recurrent papillary thyroid cancer suggests that surgery is successful in 95% of cases versus 88% with percutaneous ethanol . As a result, percutaneous ethanol is supported as an adjunct to surgery for recurrent differentiated thyroid cancer by the Thyroid Cancer Care Collaborative .…”
Section: Malignant Thyroid Diseasementioning
confidence: 99%
“…PEI offers distinct advantages over re-operation because it avoids most of the complications of surgical intervention (4). The most common complications after PEI are temporary hoarseness and local transient pain (5).…”
Section: Introductionmentioning
confidence: 99%