Percutaneous closure of post-myocardial infarction ventricular septal rupture in patients with ventricular septal rupture and apical thrombus: First case in literature

Arı, Hasan; Melek, Mehmet; Arı, Selma; Doganay, K.; Öztaş, Selvi

doi:10.1016/j.ijcard.2014.12.164

Cited by 7 publications

(5 citation statements)

References 3 publications

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“…Ventricular septal rupture occurs most often between the 3rd and 5th days after the infarction and is more frequent after anterior myocardial infarction [10]. In this case a significant leakage between the left and right ventricles, a rapid increase of symptoms of left and right ventricular failure, cardiogenic shock and escalation of already existing heart disease symptoms are reported [11].…”

Section: Types Of Mechanical Complications Of Amimentioning

confidence: 72%

“…In spite of the rapid and complete diagnostics and application of the specific treatment to an individual patient i.e. percutaneous coronary interventions (PCI), coronary artery bypass graft (CABG), a high incidence of death occurs [10,12]. Mitral regurgitation is a common complication of myocardial infarction, resulting from myocardial remodeling, displacement or rupture of the anterior, posterior or septal papillary muscle and tendinous chords that connect the muscle to the valve leaflets, limiting their closure [13].…”

Section: Types Of Mechanical Complications Of Amimentioning

confidence: 99%

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Atypical form of microscopic colitis in 56-year-old patient presenting with long-lasting watery diarrhea

Kiełtucki¹,

Zając²

2019

Ann. Acad. Med. Siles.

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Mikroskopowe zapalenie jelita grubego to częsta przyczyna przewlekłej biegunki niewiadomego pochodzenia. Choroba charakteryzuje się obecnością objawów klinicznych, makroskopowo prawidłowym wyglądem błony śluzowej jelita grubego w kolonoskopii i obecnością typowych zmian w badaniu histopatologicznym. Celem pracy jest przedstawienie nietypowego obrazu histologicznego mikroskopowego zapalenia jelita grubego. Autorzy prezentują przypadek 56-letniego mężczyzny z uporczywą, wodnistą biegunką, z pochopnie rozpoznaną niewydolnością zewnątrzwydzielniczą trzustki. Po wykluczeniu infekcyjnego tła biegunki wykonano kolonoskopię, ukazując makroskopowo niemal prawidłowy obraz jelita grubego. Otrzymano niespójne wyniki badań histopatologicznych. W badaniu mikroskopowym wycinków z okrężnicy potwierdzono rozpoznanie kolagenowego mikroskopowego zapalenia jelita grubego (w preparacie grubość kolagenu podnabłonkowego wynosiła > 10 µm, liczba limfocytów śródnabłonkowych < 20 w przeliczeniu na 100 komórek nabłonka). Tymczasem podczas kontrolnej kolonoskopii w wycinkach z jelita grubego ujawniono cechy zapalenia limfocytowego, w badanych próbkach nie wykazano obecności złogów podnabłonkowego kolagenu. Autorzy analizują czynniki ryzyka zachorowania, odpowiedź na zastosowane leczenie, przebieg kliniczny choroby oraz rozbieżne wyniki badań histopatologicznych.

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Section: Types Of Mechanical Complications Of Amimentioning

confidence: 72%

Section: Types Of Mechanical Complications Of Amimentioning

confidence: 99%

Atypical form of microscopic colitis in 56-year-old patient presenting with long-lasting watery diarrhea

Kiełtucki¹,

Zając²

2019

Ann. Acad. Med. Siles.

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“…Percutaneous TCC has have become increasingly sophisticated and can be used as an alternative to surgical closure of VSR for subacute and chronic VSR ( 48 ). When applied in patients with advanced VSR is usually associated with a high mortality rate ( 2 ).…”

Section: Discussionmentioning

confidence: 99%

Analysis of influencing factors for prognosis of patients with ventricular septal perforation: A single-center retrospective study

Duan

Zhao

et al. 2022

Front. Cardiovasc. Med.

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BackgroundVentricular septal rupture (VSR) is a type of cardiac rupture, usually complicated by acute myocardial infarction (AMI), with a high mortality rate and often poor prognosis. The aim of our study was to investigate the factors influencing the long-term prognosis of patients with VSR from different aspects, comparing the evaluation performance of the Gensini score, Sequential Organ Failure Assessment (SOFA) score and European Heart Surgery Risk Assessment System II (EuroSCORE II) score systems.MethodsThis study retrospectively enrolled 188 patients with VSR between Dec 9, 2011 and Nov 21, 2021at the First Affiliated Hospital of Zhengzhou University. All patients were followed up until Jan 27, 2022 for clinical data, angiographic characteristics, echocardiogram outcomes, intraoperative, postoperative characteristics and major adverse cardiac events (MACEs) (30-day mortality, cardiac readmission). Cox proportional hazard regression analysis was used to explore the predictors of long-term mortality.ResultsThe median age of 188 VSR patients was 66.2 ± 9.1 years and 97 (51.6%) were males, and there were 103 (54.8%) patients in the medication group, 34 (18.1%) patients in the percutaneous transcatheter closure (TCC) group, and 51 (27.1%) patients in the surgical repair group. The average follow-up time was 857.4 days. The long-term mortality of the medically managed group, the percutaneous TCC group, and the surgical repair group was 94.2, 32.4, and 35.3%, respectively. Whether combined with cardiogenic shock (OR 0.023, 95% CI 0.001–0.054, P = 0.019), NT-pro BNP level (OR 0.027, 95% CI 0.002–0.34, P = 0.005), EuroSCORE II (OR 0.530, 95% CI 0.305–0.918, P = 0.024) and therapy group (OR 3.518, 95% CI 1.079–11.463, P = 0.037) were independently associated with long-term mortality in patients with VSR, and this seems to be independent of the therapy group. The mortality rate of surgical repair after 2 weeks of VSR was much lower than within 2 weeks (P = 0.025). The cut-off point of EuroSCORE II was determined to be 14, and there were statistically significant differences between the EuroSCORE II < 14 group and EuroSCORE II≥14 group (HR = 0.2596, 95%CI: 0.1800–0.3744, Logrank P < 0.001).ConclusionPatients with AMI combined with VSR have a poor prognosis if not treated surgically, surgical repair after 2 weeks of VSR is a better time. In addition, EuroSCORE II can be used as a scoring system to assess the prognosis of patients with VSR.

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“…However, the better outcome observed with delayed repair operation is also criticized as a representation of survival bias, as many patients were too sick to wait for delayed surgery and died during the waiting period (8). Recently, percutaneous transcatheter closure (TCC) has emerged as an alternative to surgical closure of VSR but is mainly restricted to selected cases in which patients have small VSR in the subacute or chronic phase (9)(10)(11). Besides, some surgical modifications have been proposed but appear less promising due to the lack of the repeatability and effectiveness confirmed by other researchers (12)(13)(14)(15).…”

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics and Contemporary Prognosis of Ventricular Septal Rupture Complicating Acute Myocardial Infarction: A Single-Center Experience

Wang

Xiao

Liu

et al. 2021

Front. Cardiovasc. Med.

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Objectives: Ventricular septal rupture (VSR) is a rare but lethal complication of acute myocardial infarction (AMI). We conducted a retrospective analysis of the clinical characteristics of VSR patients and explored the risk factors for long-term mortality.Methods: In this single-center cohort study, 127 patients diagnosed with post-AMI VSR between May 2012 and April 2019 were included. Demographic, clinical, operative, and outcome data were collected. The 30-day and long-term mortality were outcomes of interest. Cox proportional hazard regression analysis was used to explore the predictors of long-term mortality.Results: The mean age of the VSR cohort was 66.6 ± 8.7 years, 67 (52.8%) were males. Among the 127 patients, 78 patients (61.4%) were medically managed, 31 (24.4%) patients underwent percutaneous transcatheter closure (TCC), and 18 (14.2%) patients received surgical repair. The median follow-up time was 1129 days [interquartile range: 802–2019 days]. The 30-day mortality of the medically managed group, percutaneous TCC group, and surgical management group was 93.6, 22.6, and 11.1%, respectively; and the long-term mortality was 96.2, 25.8, and 22.2%, respectively. VSR repair treatment including surgical management (HR 0.01, 95% CI 0.001–0.09, p < 0.001) and percutaneous TCC (HR 0.09, 95% CI 0.03–0.26, p < 0.001) was associated with a better prognosis, and cardiogenic shock (CS) (HR 9.30, 95% CI 3.38–25.62, p < 0.001) was an independent risk factor of long-term mortality.Conclusions: The prognosis of VSR patients without operative management remains poor, especially in those complicated with CS. Timely and improved surgery treatment is needed for better outcomes in VSR patients.

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Percutaneous closure of post-myocardial infarction ventricular septal rupture in patients with ventricular septal rupture and apical thrombus: First case in literature

Cited by 7 publications

References 3 publications

Atypical form of microscopic colitis in 56-year-old patient presenting with long-lasting watery diarrhea

Atypical form of microscopic colitis in 56-year-old patient presenting with long-lasting watery diarrhea

Analysis of influencing factors for prognosis of patients with ventricular septal perforation: A single-center retrospective study

Clinical Characteristics and Contemporary Prognosis of Ventricular Septal Rupture Complicating Acute Myocardial Infarction: A Single-Center Experience

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