Percutaneous catheter drainage of uncomplicated amoebic liver abscess: prospective evaluation of a clinical protocol for catheter removal and the significance of residual collections

Goyal, Amandeep; Dhaliwal, H. S.; Nampoothiri, Ram Vasudevan; Singh, Ripudaman; Abraham, John; Sharma, Rajan; Soloman, Rajat; Lahan, Shubham; Kaur, Preetraj; Bansal, Pankaj; Gill, Chiranjiv Singh

doi:10.1007/s00261-021-02949-5

Cited by 2 publications

(3 citation statements)

References 30 publications

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“…The two well established risk factors include large size and left lobe location; drainage has been advocated in presence of these factors, fearing that they will rupture [20,27]. Also, the thickness (< 1 cm) of liver tissue between abscess and liver margin has reportedly been used as an objective measure to assess impending rupture [2,26,28]. In this context, our results strongly point out that lack of a mature wall (type I abscesses) on CT is perhaps the single most important risk factor that must be considered while assessing rupture risk.…”

Section: Discussionmentioning

confidence: 99%

CT of amebic liver abscess: different morphological types with different clinical features

et al. 2021

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Section: Discussionmentioning

confidence: 99%

CT of amebic liver abscess: different morphological types with different clinical features

et al. 2021

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“…Thus, PCD or percutaneous needle aspiration (PNA) could be regarded as a first-line therapy for caudate lobe amebic abscess management, in adjunct to medical therapy[ 4 ]. Following substantial reduction or cessation of PCD output along with clinical recovery, treating physicians may be concerned with residual collections on radiological evaluations[ 49 ]. However, both the significance and prevalence of such collections remain unknown, and it is subsequently unclear what approach should be taken in order to tackle them.…”

Section: Treatmentmentioning

confidence: 99%

“…However, both the significance and prevalence of such collections remain unknown, and it is subsequently unclear what approach should be taken in order to tackle them. On the other hand, PCD removal can be expedited successfully in ALAs, even when residual collections are present[ 49 ]. In pediatric patients, PNA and drain placement were both found to be effective as ALA treatments, though PNA had greater efficacy[ 50 ].…”

Section: Treatmentmentioning

confidence: 99%

Amebic liver abscess by Entamoeba histolytica

Usuda¹,

Tsuge²,

Sakurai³

et al. 2022

World J Clin Cases

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Amebic liver abscesses (ALAs) are the most commonly encountered extraintestinal manifestation of human invasive amebiasis, which results from Entamoeba histolytica ( E. histolytica ) spreading extraintestinally. Amebiasis can be complicated by liver abscess in 9% of cases, and ALAs led to almost 50000 fatalities worldwide in 2010. Although there have been fewer and fewer cases in the past several years, ALAs remain an important public health problem in endemic areas. E. histolytica causes both amebic colitis and liver abscess by breaching the host’s innate defenses and invading the intestinal mucosa. Trophozoites often enter the circulatory system, where they are filtered in the liver and produce abscesses, and develop into severe invasive diseases such as ALAs. The clinical presentation can appear to be colitis, including upper-right abdominal pain accompanied by a fever in ALA cases. Proper diagnosis requires nonspecific liver imaging as well as detecting anti- E. histolytica antibodies; however, these antibodies cannot be used to distinguish between a previous infection and an acute infection. Therefore, diagnostics primarily aim to use PCR or enzyme-linked immunosorbent assay to detect E. histolytica . ALAs can be treated medically, and percutaneous catheter drainage is only necessary in approximately 15% of cases. The indicated treatment is to administer an amebicidal drug (such as tinidazole or metronidazole) and paromomycin or other luminal cysticidal agent for clinical disease. Prognosis is good with almost universal recovery. Establishing which diagnostic methods are most efficacious will necessitate further analysis of similar clinical cases.

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Percutaneous catheter drainage of uncomplicated amoebic liver abscess: prospective evaluation of a clinical protocol for catheter removal and the significance of residual collections

Cited by 2 publications

References 30 publications

CT of amebic liver abscess: different morphological types with different clinical features

CT of amebic liver abscess: different morphological types with different clinical features

Amebic liver abscess by Entamoeba histolytica

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