Amebic liver abscess by <i>Entamoeba histolytica</i>

Usuda, Daisuke; Tsuge, Shiho; Sakurai, Riki; Kawai, Kenji; Matsubara, Shun; Tanaka, Risa; Takano, Hayabusa; Shimozawa, Shintaro; Hotchi, Yuta; Tokunaga, Shungo; Osugi, Ippei; Katou, Risa; Ito, Sakurako; Mishima, Kentaro; Kondo, Akihiko; Mizuno, Keiko; Takami, Hiroki; Komatsu, Takayuki; Oba, Jiro; Nomura, Tomohisa; Sugita, Manabu

doi:10.12998/wjcc.v10.i36.13157

Cited by 12 publications

(15 citation statements)

References 59 publications

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“…Upon contamination, there is excystation of the parasite within the small intestines, followed by the invasion of the trophozoites that lyse the colonic epithelium. As part of the inflammatory process, neutrophils then further damage the colonic epithelium leading to extraintestinal contamination via hematogenous spread to the liver and peritoneum resulting in further necrosis, abscess formation, and perforation [ 2 , 7 - 9 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of Entamoeba histolytica Liver Abscess in an Immigrant Patient

Balaji,

Ignatowicz,

Bhushan

et al. 2024

Cureus

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Entamoeba histolytica is a pathogenic protozoan endemic to Asia, Africa, and Central and South America. However, with increased travel and emigration, it is becoming a common parasitic infection leading to many worldwide deaths. We present a case of a young Hispanic male immigrant with an amebic liver abscess. This case report highlights the complexities of diagnosing and treating E. histolytica infection.

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Section: Discussionmentioning

confidence: 99%

A Case of Entamoeba histolytica Liver Abscess in an Immigrant Patient

Balaji,

Ignatowicz,

Bhushan

et al. 2024

Cureus

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“…Such differentiation is crucial in order to prevent a delay in the implementation of appropriate therapy. Determination of an accurate diagnosis of ALA relies mainly on laboratory tests that use immunological, molecular, and parasitological methods to confirm EH in different specimens[ 55 ].…”

Section: Diagnostic Issues and Advancesmentioning

confidence: 99%

Amebic liver abscess: An update

Kumar,

Patel,

Priyadarshi

et al. 2024

World J Hepatol

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Amebic liver abscess (ALA) is still a common problem in the tropical world, where it affects over three-quarters of patients with liver abscess. It is caused by an anaerobic protozoan Entamoeba hystolytica , which primarily colonises the cecum. It is a non-suppurative infection of the liver consisting primarily of dead hepatocytes and cellular debris. People of the male gender, during their reproductive years, are most prone to ALA, and this appears to be due to a poorly mounted immune response linked to serum testosterone levels. ALA is more common in the right lobe of the liver, is strongly associated with alcohol consumption, and can heal without the need for drainage. While majority of ALA patients have an uncomplicated course, a number of complications have been described, including rupture into abdomino-thoracic structures, biliary fistula, vascular thrombosis, bilio-vascular compression, and secondary bacterial infection. Based on clinico-radiological findings, a classification system for ALA has emerged recently, which can assist clinicians in making treatment decisions. Recent research has revealed the role of venous thrombosis-related ischemia in the severity of ALA. Recent years have seen the development and refinement of newer molecular diagnostic techniques that can greatly aid in overcoming the diagnostic challenge in endemic area where serology-based tests have limited accuracy. Metronidazole has been the drug of choice for ALA patients for many years. However, concerns over the resistance and adverse effects necessitate the creation of new, safe, and potent antiamebic medications. Although the indication of the drainage of uncomplicated ALA has become more clear, high-quality randomised trials are still necessary for robust conclusions. Percutaneous drainage appears to be a viable option for patients with ruptured ALA and diffuse peritonitis, for whom surgery represents a significant risk of mortality.With regard to all of the aforementioned issues, this article intends to present an updated review of ALA.

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“…The chest X-ray showed improvement within one week (Figure 1) and was normal at the end of therapy. caused by Entamoeba histolytica [3], and hydatid disease, caused by the tapeworm Echinococcus granulosus [4]. The cases mostly remain subclinical, but they may be symptomatic.…”

Section: Case Presentationmentioning

confidence: 99%

A Rare Case of Charcot-Leyden Crystals In liver biopsy in a 14-Year-Old Boy with Persistent Fever and Miliary Infiltrates

Dey¹

2023

J Intern Med Emerg Res.

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The presence of Charcot-Leyden Crystals in liver biopsy is rare. A report case of a 14-year-old boy who presented with persistent fever and respiratory symptoms. Chest X-ray and CT thorax showed miliary infiltrates. The Mantoux test was positive and sputum for acid-fast bacilli (AFB) was negative. The patient started antitubercular therapy (ATT). There was no response and the patient still had fever. Further evaluation with an ultrasound of the abdomen revealed multiple small liver abscesses with septic emboli in the spleen. Since the patient was non-responsive to antibiotics, biopsy from the lesion in the liver was suggested. Biopsy report revealed Charcot-Leyden crystals with no granulomas. The Patient was diagnosed as a case of systemic parasitic infestation. Albendazole under steroid cover was prescribed and the patient was afebrile on follow-up. It was concluded that the presence of CLCs in a biopsy specimen is rare but may be a cause of an underlying parasitic infestation. Early diagnosis and treatment with antiparasitic drugs can lead to a favorable outcome.

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Amebic liver abscess by Entamoeba histolytica

Cited by 12 publications

References 59 publications

A Case of Entamoeba histolytica Liver Abscess in an Immigrant Patient

A Case of Entamoeba histolytica Liver Abscess in an Immigrant Patient

Amebic liver abscess: An update

A Rare Case of Charcot-Leyden Crystals In liver biopsy in a 14-Year-Old Boy with Persistent Fever and Miliary Infiltrates

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