1991
DOI: 10.1007/bf02635529
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Percutaneous biopsy of the liver

Abstract: Retrospective evaluation of 510 percutaneous CT-guided biopsies of the liver mainly fine-needle aspiration biopsies for cytology (89% of cases), yielded an overall accuracy rate of 92% and a sensitivity of 94%. The relatively high percentage of false-positive diagnoses (7% of all benign tumors) may be reduced by more consistent consideration of possible errors in cytology and a more consistent use of large bore biopsies.

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Cited by 17 publications
(3 citation statements)
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“…The results of hepatic biopsies are highly reliable. In a retrospective study of 510 percutaneous liver biopsies, sensitivity was 94% without any significant difference between metastases and primary carcinomas (32). Specificity was 93% and the false‐negative rate was 5%, which is comparable to other studies on FNABs of hepatic lesions (52).…”
Section: Liver and Gallbladdermentioning
confidence: 99%
“…The results of hepatic biopsies are highly reliable. In a retrospective study of 510 percutaneous liver biopsies, sensitivity was 94% without any significant difference between metastases and primary carcinomas (32). Specificity was 93% and the false‐negative rate was 5%, which is comparable to other studies on FNABs of hepatic lesions (52).…”
Section: Liver and Gallbladdermentioning
confidence: 99%
“…The most frequent minor complication was isolated pain; subsequent CT revealed small hematomas, which are often seen after organ biopsy, in the majority of those patients. Several studies have previously shown the safety of percutaneous liver biopsy in general, with major hemorrhage occurring in 0-3.4% of patients [25][26][27][28][29][30][31][32][33][34]. Furthermore, a retrospective study of 38 hepatic cavernous hemangioma biopsies concluded that the procedure is safe, with no major complications [35].…”
Section: Discussionmentioning
confidence: 99%
“…ZusammenfassungTrotz der Fortschritte der Schnittbildverfahren und der operativen Verfahren kommen bildgesteuerte Interventionen bei Lebertumoren sowohl im Rahmen der Diagnostik als auch der onkologischen Therapie weiterhin zum Einsatz.CT-gesteuerte Biopsien sollten mit16-18 g-Stanzbiopsienadeln entnommen werden und sind den Fällen vorbehalten, die sonographisch unmöglich oder risikoreich sind.MRT gesteuerte Eingriffe sind noch selten.Die Treffsicherheiten der perkutanen Biopsiegewinnung liegen >90%, die Komplikationsraten, v.a.Blutung <1%.Palliative bildgesteuerte Interventionen von primären und sekundären Lebermalignomen sind thermoablative Verfahren über Laser (LITT), Kryoablation, Radiofrequenztherapie, die perkutane Alkoholinjektion (PEI) sowie lokale Chemotherapieverfahren über operativ oder perkutan implantierte Portsysteme in die A.hepatica oder über wiederholte transarterielle Katheterisierung im Rahmen von Chemoembolisationen und Chemoperfusionen (TACE).Bei Lebermetastasen sind bei geringer Größe (<4 cm) und Zahl (<5) LITT und PEI empfehlenswert, in fortgeschrittenen Fällen die Chemotherapie via Port.Für das HCC zeigt die PEI gute Ergebnisse, in den Stadien UICC IIIB und IV kommt die TACE zum Einsatz.…”
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