Perceptual organization in first episode schizophrenia and ultra-high-risk states

Silverstein, Steven M.; Uhlhaas, Peter J.; Essex, Brian; Halpin, Sean; Schall, Ulrich; Carr, Vaughan J.

doi:10.1016/j.schres.2006.01.003

Cited by 49 publications

(45 citation statements)

References 61 publications

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“…Silverstein et al (2006) also failed to find differences between FEP and ARMS and, in this single case, the performance of these groups did not differ from that of healthy volunteers in assessments of perceptual organization, suggesting the preservation of this function. It should be noted that this study did not control for the and education of participants and, according to the authors, it had an important limitation related to possible biases in the selection of volunteers in ARMS, which could explain the absence of the deficit reported.…”

Section: Basic Cognitionmentioning

confidence: 50%

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Cognition in at-risk mental states for psychosis

Paula

Hallak

Maia‐de‐Oliveira

et al. 2015

Neuroscience & Biobehavioral Reviews

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Section: Basic Cognitionmentioning

confidence: 50%

“…The only exception was the study of Silverstein et al, 2006 that revealed no differences between the experimental groups and healthy volunteers.…”

Section: Basic Cognition In Armsmentioning

confidence: 98%

Cognition in at-risk mental states for psychosis

Paula

Hallak

Maia‐de‐Oliveira

et al. 2015

Neuroscience & Biobehavioral Reviews

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“…Silverstein et al (2006) did not find any differences between 70 HR subjects and normal controls in a perceptual organization task in terms of reaction time and accuracy. The authors conclude that abnormal perceptual organization is not a feature of risk status, but linked to chronicity in schizophrenia, to disorganized symptoms, and maybe to neuroleptic medication.…”

Section: Perceptual (Preattentive) Abilitiesmentioning

confidence: 56%

“…Using a perceptual organization task, Silverstein et al (2006) did not find any differences between converters to psychosis (n = 24) and those HR subjects who developed mood disorders after 1.5-2 years. Another study (Walder et al 2008) could not identify significantly different baseline assessments for converters (n = 12) and nonconverters after 4 years in fullscale IQ (WAIS), verbal and visual memory (WMS), and verbal working memory (LNS).…”

Section: Review Of Studies With Follow-up Datamentioning

confidence: 68%

Neurocognitive Indicators of Clinical High-Risk States for Psychosis: A Critical Review of the Evidence

Pukrop

Klosterkötter

2010

Neurotox Res

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The present review investigates the empirical evidence from cross-sectional and long-term follow-up studies on neurocognitive indicators of an increased risk for developing schizophrenia spectrum psychoses in clinically defined high-risk samples. First, the investigations at the Cologne center for early recognition and intervention are briefly summarized and then integrated within the available literature. Thirty-two studies with original data could be identified by extensive literature search. Cross-sectional investigations of neurocognitive baseline assessments in high-risk samples with unknown conversion status have produced rather inconsistent results. Nevertheless, most convincing evidence could be collected for abnormal functioning in processing speed measures (digit symbol coding, Trailmaking Test-B, Stroop Color Naming), the Continuous Performance Test, verbal working memory measures, verbal memory and learning, and verbal fluency, though negative findings have also been reported in every instance. Moreover, high-risk subjects were found to perform both at the schizophrenia performance level and at a close to normal level. Longitudinal follow-up assessments provided predictive evidence with regard to psychosis conversion for measures of processing speed and of verbal memory and learning. However, a substantial number of negative findings does not allow for straight-forward conclusions. Finally, some reasons for inconsistent findings are discussed critically speculating on demographic differences, reliability and sample sizes, and conceptual imprecision in communicating results.

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“…105 The transition rate to psychosis after a 12-month period was 50%. 106 In a further study, 107 70 UHR patients were compared with FEP patients and 24 comparable, subjects using an adapted task with known sensitivity to perceptual organization deficits in schizophrenia (adapted from 108 ) and whose scores have predicted long-term outcome and disorganized symptomatology. There was no difference between the groups on this task.…”

Section: Psychological Assistance Service (Pas)mentioning

confidence: 99%