Perceptions of breast and cervix cancer prevention in two populations of women in Peru: Impact of knowledge and access to health service

Alarcon-Rozas, A. E.; Villacres, K.; Cárdenas, Ramón A Saade

doi:10.1200/jco.2005.23.16_suppl.6120

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previously published data for the region described LABC frequencies ranging between 15% and 30% [26]. Education and health promotion is a major issue in the region and the availability of facilities for cancer screening does not imply a vast use of these services [2].…”

Section: High Burden Of Locally Advanced/advanced Bcmentioning

confidence: 99%

Barriers in Latin America for the management of locally advanced breast cancer

Pinto

Pinillos

Villarreal‐Garza

et al. 2019

ecancer

View full text Add to dashboard Cite

Breast cancer (BC) is a highly prevalent malignancy in Latin American women, most cases being diagnosed at locally advanced or metastatic stages when options for cancer care are limited. Despite its label as a public health problem in the region, Latin American BC patients face several barriers in accessing standard of care treatment when compared with patients from developed countries. In this review, we analyse the landscape of the four main identified barriers in the region: i) high burden of locally advanced/advanced BC; ii) inadequate access to medical resources; iii) deficient access to specialised cancer care and iv) insufficient BC research in Latin America. Unfortunately, these barriers represent the main factors associated with the BC poor outcomes seen in the region. Targeted actions should be conducted independently by each country and as a region to overcome these limitations and create an enhanced model of BC care.

show abstract

Section: High Burden Of Locally Advanced/advanced Bcmentioning

confidence: 99%

Barriers in Latin America for the management of locally advanced breast cancer

Pinto

Pinillos

Villarreal‐Garza

et al. 2019

ecancer

View full text Add to dashboard Cite

show abstract

“…In this context, it appears necessary to make efforts so TNBC patients can start their adjuvant therapies as soon as possible. Although there has been increased awareness and efforts for health education and promotion in the Latin region, access to specialized cancer centers and coverage of drug health insurance is limited (36,37),. This situation hinders the first contact with the health service and the initiation of treatment, which is why the process takes about seven months in countries such as Brazil and Mexico (38).…”

Section: Discussionmentioning

confidence: 99%

Subpopulation treatment effect pattern plot analysis: a prognostic model for distant recurrence-free survival to estimate delayed adjuvant chemotherapy initiation effect in triple-negative breast cancer

Morante,

Ferreyra,

Pinto

et al. 2023

Front. Oncol.

View full text Add to dashboard Cite

IntroductionTriple-negative breast cancer (TNBC) is a heterogeneous disease associated with a poor prognosis. Delaying in time to start adjuvant chemotherapy (TTC) has been related to an increased risk of distant recurrence-free survival (DRFS). We aimed to develop a prognostic model to estimate the effects of delayed TTC among TNBC risk subgroups.Materials and methodsWe analyzed 687 TNBC patients who received adjuvant chemotherapy at the Instituto Nacional de Enfermedades Neoplasicas (Lima, Peru). Database was randomly divided to create a discovery set (n=344) and a validation set (n=343). Univariate and multivariate Cox regression models were performed to identify prognostic factors for DRFS. Risk stratification was implemented through two models developed based on proportional hazard ratios from significant clinicopathological characteristics. Subpopulation treatment effect pattern plot (STEPP) analysis was performed to determine the best prognostic cut-off points for stratifying TNBC subgroups according to risk scores and estimate Kaplan-Meier differences in 10-year DRFS comparing TTC (≤30 vs.>30 days).ResultsIn univariate analysis, patients aged ≥70 years (HR=4.65; 95% CI: 2.32-9.34; p=<0.001), those at stages pT3-T4 (HR=3.28; 95% CI: 1.57-6.83; p=0.002), and pN2-N3 (HR=3.00; 95% CI: 1.90-4.76; p=<0.001) were notably associated with higher risk. STEPP analysis defined three risk subgroups for each model. Model N°01 categorized patients into low (score: 0–31), intermediate (score:32–64), and high-risk (score: 65–100) cohorts; meanwhile, Model N°02: low (score: 0–26), intermediate (score: 27–55), and high (score: 56–100). Kaplan-Meier plots showed that in the discovery set, patients with TTC>30 days experienced a 17.5% decrease in 10-year DRFS rate (95%CI=6.7-28.3), and the impact was more remarkable in patients who belong to the high-risk subgroup (53.3% decrease in 10 years-DRFS rate). Similar results were found in the validation set.ConclusionsWe developed two prognostic models based on age, pT, and pN to select the best one to classify TNBC. For Model N°02, delayed adjuvant chemotherapy conferred a higher risk of relapse in patients ≥70 years and who were characterized by pT3/T4 and pN2/N3. Thus, more efforts should be considered to avoid delayed TTC in TNBC patients, especially those in high-risk subgroups.

show abstract

“…En nuestra investigación observamos que del total de participantes sólo el 16,9% (368/2183) de mujeres peruanas de 40 a 49 años cuentan con mamografía de tamizaje. Este resultado dista a lo reportado en otros estudios en Perú, como el realizado en Sullana por Villacrés quien reportó que sólo un 7% se realizó una mamografía anual (12) ; asimismo, Alarcón en Comas, un distrito periférico de Lima, encontró un porcentaje menor al 8% de realización de mamografías (17) . Esto puede explicarse por la dimensión nacional de nuestro estudio; sin embargo, los resultados tampoco son coherentes con lo evidenciado en estudios internacionales, , o los estudios de Malak (18) y Masuet (19) , en España, los que reportaron tasas de realización de un 59% y 42,8%, respectivamente.…”

Section: Discussionunclassified

Factores asociados a la toma de mamografía en mujeres peruanas: análisis de la Encuesta Demográfica de Salud Familiar, 2015

Alegría-Delgado

Huamani-Navarro

2019

An Fac med

View full text Add to dashboard Cite

Introducción: El cáncer de mama es la neoplasia más común a nivel mundial en mujeres, y en el Perú es la segunda causa de muerte por cáncer. Objetivo: Determinar los factores sociodemográficos asociados a la toma de mamografía en mujeres peruanas durante el año 2015. Métodos: Estudio transversal. Se seleccionaron los datos de mujeres de 40 a 49 años, provenientes de la Encuesta Demográfica y de Salud Familiar (ENDES), 2015. Los factores sociodemográficos estudiados incluyeron al nivel educativo, estado marital, nivel educativo y edad de la pareja, edad al momento del matrimonio, índice de riqueza, lugar de residencia y región natural de residencia. Resultados: Se incluyeron 2183 mujeres, el 57,6% refirió tener secundaria completa, 64% tuvo pareja, 24,8% fue muy pobre, y 72,1% vivía en área rural. Los factores asociados a la toma de una mamografía fueron tener pareja con estudios superiores, edad al matrimonio de 25 años a más, y residencia urbana (costa y Lima Metropolitana). Conclusiones: Según la ENDES 2015, sólo el 16,9% de mujeres peruanas de entre 40 y 49 años se realizó una mamografía, existiendo factores sociodemográficos asociados a la realización de la misma.

show abstract

Perceptions of breast and cervix cancer prevention in two populations of women in Peru: Impact of knowledge and access to health service

Cited by 4 publications

References 0 publications

Barriers in Latin America for the management of locally advanced breast cancer

Barriers in Latin America for the management of locally advanced breast cancer

Subpopulation treatment effect pattern plot analysis: a prognostic model for distant recurrence-free survival to estimate delayed adjuvant chemotherapy initiation effect in triple-negative breast cancer

Factores asociados a la toma de mamografía en mujeres peruanas: análisis de la Encuesta Demográfica de Salud Familiar, 2015

Contact Info

Product

Resources

About