Peptides. XX. Synthesis of the octadecapeptide corresponding to the entire amino acid sequence of monkey .beta.-melanocyte-stimulating hormone

Lipolytic activity of Met-Arg-His-Phe-Arg-Trp-Gly, a synthetic analog of the ACTH (4-10) core sequence

“…This would greatly enhance the binding of the 5-arginine analog of the hormone to the receptor, A very interesting observation of Yajima, et ai, on synthetic monkey /3-MSH intermediates should be considered. 51 In their synthetic procedure, intermediates of increasing length at the N terminus were available and were assayed for melanocyte-stimulating activity. peptide containing an N-terminal methionine (the methionine of the core heptapeptide) with the next peptide in their synthetic series, in which an additional N-terminal arginine had been added, shows that addition of the basic residue results in a large increase in biological activity.…”

Trifluoroethanol-containing RP-HPLC mobile phases for the separation of transmembrane peptides human glycophorin-A, integrin alpha-1, and p24: analysis and prevention of potential side reactions due to formic acid

“…In a final effort, we attempted to establish conditions that removed the formyl groups from the Ser residue and the N‐terminus of the TM peptides. Because TM peptides are insoluble in the solvents commonly used for cleavage of formyl esters and formyl amides, such as water, aqueous dioxane, THF, EtOH, or MeOH , our efforts focused on their selective removal in HFIP‐ or TFA‐containing solvents. The reactions were screened using MALDI‐TOF‐MS as described in Table .…”

Reactions of proteins, carbohydrates, and related substances in liquid hydrogen fluoride

“…DL-Arabinitol pentaacetate (37) formed all three pentitols, arabinitol (38), ribitol (39), and xylitol (40) in HF.56 Ring closing to form anhydroglycitols was not observed with any of the fully acylated hexitols or pentitols studied. However, HF treatment of a partially acylated hexitol,…”