Peptic Ulcer in Town and Country

Prevalence of Peptic Ulcer in Dyspeptic Patients and the Influence of Age, Sex, and Helicobacter pylori Infection

“…may contribute to the development of ulcer disease. In fact, the influence of sex and age on ulcer disease was observed before the discovery of H. pylori [19,20]. In this study, we disclosed that the prevalence of gastric and duodenal ulcers increased with age and that there was a markedly higher prevalence in patients aged C60 years, especially in the prevalence of gastric ulcer.…”

Comments on the incidence and natural history of gastric and duodenal ulcer

“…During our survey in York (1952-57) (Pulvertaft, 1959) it was noted that the number of new cases of male duodenal ulcer diagnosed per year in the City of York was falling, but this was not happening in the surrounding country area.…”

“…One of the simplest methods is the study of acute perforations, and several population sur-veys, in this country and Australia (Pulvertaft, 1959;Billington, 1960a, b) have shown that acute perforations represent some 11% of the chronic ulcer population; in a recent study Sanders (Sanders, 1967) has suggested that it is possible to use perforation incidence as an indication of total ulcer numbers.…”

“…In the 1950s there were three studies reporting acute perforation, one from Glasgow (Jamieson, 1955), one from Aberdeen (Weir, 1960), and one from York (Pulvertaft, 1959).…”

Peptic ulcer in India and its aetiology

“…Konstam (1954) ascribed the high incidence in his Nigerian study to vitamin B deficiency. Pulvertaft (1959) has observed that ulcer in his series was more common in popula- Aird (1961), the importance of these specific blood group substances in peptic ulcer depends upon some interaction in the cell membrane itself. Such a reaction might well have an immunological basis.…”